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옥광휘,정용구,박윤관,정흥섭,이훈갑,이기찬,주정화 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.6
A case of cystic acoustic Neurinoma is reported. The Patient was 41 year old man with temporal lobe epilepsy. Computerized tomography disclosed a low density cystic mass at left cerebellopontine angle that extended to suprasellar cistern through tentorium. At operation, multiloculated cysts were found that looked like cysticercosis. Pathological examination revealed a typical neurilemmoma with Antoni A and B area that formed cyst wall.
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白鼠의 中大腦動脈의 폐쇄와 재관류에 대한 실험모양인 頭蓋腔外 접근법과 經頭蓋腔 접근법에 대한 비교연구 : Extracranial and Transcranial Methods
玉光輝,朱正和,李勳甲,徐中根,鄭興燮,朴倫寬,李基燦 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.22 No.5
The author described a comparative study of 2 different expenemental methods of reperfusion models in rat ; 1) transcranial method(TC) and 2) extracranial method(EC). The transcranial method was performed by a direct approach to the middle cerebral artery(MCA) after temporozygomatic craniotomy in which a wire was hooked on the proximal portion of middle cerebral artery(MCA) and pulled it to make occlusion of MCA. For the extracranial method a nylon surgical thread was inserted intraluminally along the internal carotid artery(ICA) to reach the anterior communicating artery. Recirculation of blood was accomplished by removal of the hook or of the thread after 4 hours occlusion of MCA. Two different models were subdivided into 4 chronological goups pre-reperfusion, 30 minutes, 2 hours, and 48 hours after reperfusion. The differences were evaluated with morphometric analysis after neutral red(NR) or tetrazolium salt(TTC) staining. From the evaluation of initial ischemic area, the extracranial method showed a larger infarct volume as compared to the transcranial method(p=0.013). Mean value(SD) of infarcted area of EC and TC were 28.7% (4.4%) and 14.4% (8.1%) respectively. Recovery from the initial ischemia after reperfusion was gradually achieved in both of two groups(p<0.05). The restoration of blood flow after reperfusion was more rapid in EC group and only 2 hours reperfusion was enough to show no difference between two methods. In TC group followed by 48 hours' reperfusion, 40% of animals resulted in gross infarction of MCA temtory as noted with TTC stain, most probably due to reperfusion failure. EC group showed only one such a case(12.5 %). But this difference was not in the range of significance statistically. From a technical point of view, EC was more simple, needed less time since a craniotomy was not performed. and required no manipulation of the brain or any intracranial vessels. From these results the author concluded that the extracranial method is a more reliable and technically more manageable one to be used as a reperfusion model for investigating the focal cerebral ischemia.
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옥광휘,이기찬 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.7
The informations obtained from epidemiology of brain tumor provide the key to the natural history of brain tumors and could be used for many different things, among others, the planning of hospitals and hospital care facilities and working out the medical requirements for each region. To cope with changing needs in this field due to the application of medical insurance to all Korean citizens from July 1, 1989, the brain tumor registries of various countries were reviewed and suggestions were made about Korean Brain Tumor Registry that should be prepared in the near future.
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옥광휘,정흥섭,서중근,이훈갑,주정화 대한신경외과학회 1987 Journal of Korean neurosurgical society Vol.16 No.4
Visual evoked potentials were elicited by flash in 29 patients with a variety of cerebral lesions and in 10 normal controls. In 12 patients with focal brain lesions, no wave form could be recorded in one side. Of the remaining 23 sides, the average P₁ latency showed no difference from that of the normal controls. In 17 patients with diffuse brain lesions no wave form could be elicited in 12 sides. Average P₁ latency of remaining 22 sides showed statistically significant difference from that of normal controls. In this study it appears that delayed P₁ latencies are associated with diffuse cerebral lesions rather than with localized lesions.
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白鼠의 中大腦動脈의 폐쇄와 재관류에 대한 실험모양인 頭蓋腔外 접근법과 經頭蓋腔 접근법에 대한 비교연구 : Extracranial and Transcranial Methods
玉光輝,朱正和,李勳甲,徐中根,鄭興燮,朴倫寬,李基燦 고려대학교 의과대학 1993 고려대 의대 잡지 Vol.30 No.1
The author described a comparative study of 2 different experimental methods of reperfusion models in rat ; 1) transcranial method (TC) and 2) extracranial method (EC). The transcranial method was performed by a direct approach to the middle cerebral artery (MCA) after temporozygomatic craniotomy in which a wire was hooked on the proximal portion of middle cerebral artery (MCA) and pulled it to make occlusion of MCA. For the extracranial method, a nylon surgical thread was inserted intraluminally along the internal carotid artery (ICA) to reach the anterior communicating artery. Recirculation of blood was accomplished by removal of the hook or of the thread after 4 hours occlusion of MCA. Two different models were subdivided into 4 chronological groups : pre-reperfusion, 30 minutes, 2 hours, and 48 hours after reperfusion. The differences were evaluated with morphometric analysis after neutral red (NR) or tetrazolium salt (TTC) staining. From the evaluation of initial ischemic area, the extracranial method showed a larger infarct volume as compared to the transcranial method (p=0.013). Mean value (SD) of infarcted area of EC and TC were 28.7% (4.4%) and 14.4% (8.1%) respectively. Recovery from the initial ischemia after reperfusion was gradually achieved in both of two groups (p<0.05). The restoration of blood flow after reperfusion was more rapid in EC group and only 2 hours' reperfusion was enough to show no difference between two methods. In TC group followed by 48 hours' reperfusion 40% of animals resulted in gross infarction of MCA territory as noted with TTC stain, most probably due to reperfusion failure. EC group showed only one such a case (12.5%). But this difference was not in the range of significance statistically. From a technical point of view, EC was more simple, needed less time since a craniotomy was not performed, and required no manipulation of the brain or any intracranial vessels. From these results the author concluded that the extracranial method is a more reliable and technically more manageable one to be used as a reperfusion model for investigating the focal cerebral ischemia.
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