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고도로 상승된 혈중 CA - 125 를 보이는 비파열 자궁내막종 1 예
오희숙(Hee Suk Oh),조수용(Soo Yong Chough),박용균(Yong Kyun Park),서호석(Ho Suk Saw),김철환(Chul Hwan Kim),허준용(Jun Young Hur) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.2
CA-125 is an antigenic determinant expressed by more than 80% epithelial ovarian cancer. Although developed for use in the diagnosis and monitoring of epithelial ovarian cancer, elevations of CA-125 concentrations can also be associated with some normal physiologic conditions, various other malignancies and benign conditions. Adnexal cysts are frequently encountered during the reproductive years. 10 to 35% of benign cystic adnexal masses may be an endometrioma. Because endometriomas are not likely to resolve spontaneously, and may enlarge or rupture during period of observation, a test to detect an endometrioma would assist in the evaluation and management of adnexal cysts. Serum CA-125 concentration is seldom >100 U/ml in endometriosis. We reported a patient with endometrioma presenting with a very high CA-125 concentration, which may confuse diagnosis with ovarian cancer.
Epithelioid Trophoblastic Tumor
신정호 ( Jung Ho Shin ),오희숙 ( Hee Suk Oh ),조수용 ( Soo Yong Chough ),서호석 ( Ho Suk Saw ),허준용 ( Jun Young Hur ),김철환 ( Chul Hwan Kim ),송승훈 ( Seung Hun Song ),김육재 ( Yuk Jae Kim ) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.7
Epithelioid trophoblastic tumor (EIT) is an unusual variant of gestational trophoblastic tumor that is closely related to choriocarcinoma and placental site trophoblastic tumor (PSTT) but shows different morphologic, immunohistochemical features. EIT grows in a nodular pattern compared with the infiltrative pattern of PSlT. Histologically the tumor is characterized by uniform population of mononucleate intermediate trophoblastic cells that resemble the trophoblastic cells in the chorionic laeve, so we called them chorionic-type intermediate trophoblast. Immunohistochemically ETT was positive for cytokeratin, epithelial membrane antigen(EMA) and staining for human placental lactogen (hPL) and human chorionic gonadotrophin (hCG) was generally patchy, focal or negative whereas PSlT contained more hPL-positive cells than hCG-positive cells. EIT can behave in a malignant fashion such as distant metastasis. We experienced a case of E1T by clinical result, pathologic finding, so we report a case with brief literature review.
자궁 경부 임신과 자궁내 임신이 동시에 발생 한 1 예
황종하(Jong Ha Hwang),신정호(Jung Ho Shin),송승훈(Sung Hun Song),오희숙(Hee Suk Oh),이린화(Lynn Hwa Lee),이미정(Mi Jung Lee),허준용(Jun Young Hur),서호석(Ho Suk Saw),박용균(Young Kyun Park),조수용(Soo Yong Chough) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.12
N/A Although recently the incidence of heterotopic pregnancies are increasing because of assisted reproduction, heterotopyic pregnancies were rare with an incidence of 1 per 30,000 pregnancies. In this presentation, we describe a case of combined intrauterine and cervical pregnancy after artificial abortion. The patient was treated by local injection of methotrexate directly into gestational sac under the guidance of sonogram after systemic methotrexate treatment. The gestational products were removed by dilatation & currettage due to persistent vaginal bleeding on the next day. So we report a case with a brief review of the literatures.