선천눈꺼풀처짐 환자에서 보존대퇴근막의 눈꺼풀판 고정이 이마근걸기술의 결과에 미치는 영향

오주연,김철,정호경,곽상인,Joo Youn Oh,M,D,Cheol Kim,M,D,Ho Kyung Chung,M,D,Sang In Khwarg,M,D,Ph,D 대한안과학회 2006 대한안과학회지 Vol.47 No.1

Purpose: To evaluate the efficacy of tarsal fixation of fascia in frontalis sling surgery using preserved fascia lata in congenital ptosis patients. Methods: The authors retrospectively investigated the surgical results of congenital ptosis patients who underwent frontalis sling procedure using preserved fascia lata with or without tarsal fixation. Thirty-nine patients were included in the group with tarsal fixation of fascia and 43 in the group without tarsal fixation. The average age at operation was 59.3 months in the tarsal fixation group, and 64.7 months in the group without tarsal fixation. We compared the recurrence rates between the two groups using the survival analysis. Results: Recurrence occurred in 13 patients of the tarsal fixation group (33.3%) and in 20 of the group without tarsal fixation (46.5%). The two groups’ median survival times from operation to recurrence were 28.4 months and 26.1 months, respectively (p=0.64). Conclusions: Tarsal fixation of fascia did not have a significant influence on recurrence rates in congenital ptosis patients who underwent a frontalis sling operation using preserved fascia lata.

공막돌륭술 후 재발된 열공성 망막박리에서 유리체절제술의 효과

오주연(Joo Youn Oh),유형곤(Hyeong Gon Yu) 대한검안학회 2007 Annals of optometry and contact lens Vol.6 No.1

목적: 열공성 망막박리에서 공막돌륭술로 망막이 유착되었다가 재발된 경우 유리체절제술의 효과를 알아보고자 하였다. 대상과 방법: 열공성 망막박리로 공막돌륭술을 시행하고 망막이 6주 이상 재유착되었다가 재발된 환자에서 유리체절제술을 시행한 경우 그 임상결과를 분석하였다. 결과: 246명 중 망막박리가 재발되어 유리체절제술을 시행받은 경우는 31명(12.6%)이었다. 수술 전에 황반부를 침범한 경우가 31안 중 23안(74.2%)이었고 증식유리체망막병증은 11안(35.5%)에서 동반되어 있었다. 가스충전은 21안(67.7%)에서 하였고, 10안(32.3%)에서 실리콘오일을 주입하였다. 초음파 유화술과 인공수정체삽입이 5안에서, 수정체절제술이 4안에서 동시에 시행되었다. 유리체절제술 후 6안에서 망막박리가 재발하여 5안에서 이차 유리체절제술로써 망막이 재유착되어 최종 검사상 30안(96.8%)에서 해부학적인 성공을 나타내었다. Snellen 시력 0.1 이상의 기능적 성공은 19안(61.3%)에서만 나타났다. 결론: 단순 열공성 망막박리 환자에서 성공적인 공막돌륭술 후에도 정기적인 추적관찰이 필요하며 재발하였을 경우 유리체절제술이 유용한 치료방법이 될 수 있다. Purpose: To evaluate the surgical outcome of pars plana vitrectomy for the treatment of the recurrent rhegmatogenous retinal detachment more than 6 weeks after reattachment with primary scleral buckling procedures. Methods: We reviewed the clinical and operative records of 31 eyes of 31 patients who underwent pars plana vitrectomy for the treatment of the recurrent retinal detachment more than 6 weeks after reattachment with primary scleral buckling procedures. Anatomical and functional outcomes were analyzed. Results: Of total 246 patients who had achieved a retinal reattachment after scleral buckling, redetachment occurred in 31 patients from 6 weeks to 36 months (average, 10.1 months). Macula was involved in 23 of 31 patients (74.2%) and proliferative vitreoretinopathy was combined in 11 eyes (35.5%). Gas injection was done in 21 eyes (67.7%), and silicone oil was injected in 10 eyes (32.3%), intraoperatively. hacoemulsification and intraocular lens implantation in 5 eyes and lensectomy in 4 eyes were performed simultaneously with pars plana vitrectomy. Retina was redetached in 6 patients, of which 5 patients had a second vitrectomy. Overall, 30 patients (96.8%) achieved an anatomic success, while only 19 eyes (61.3%) achieved a visual acuity of better than 0.1 in Snellen chart. Conclusions: Regular follow-up is necessary for the patients with rhegmatogenous retinal detachment, even after successful scleral buckling, and pars plana vitrectomy can be useful for recurrent retinal detachment in these patients.

맥락막신생혈관을 합병한 연령관련황반변성 환자에서 망막신경섬유층촬영을 이용한 신경절세포의 분석

오주연 ( Joo Youn Oh ),정태영 ( Tae Young Chung ),김동명 ( Dong Myung Kim ),유형곤 ( Hyeong Gon Yu ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

맥락막신생혈관을 합병한 연령관련황반변성 환자에서 망막신경섬유층촬영을 이용한 신경절세포의 분석

오주연 ( Joo Youn Oh ) , 정태영 ( Tae Young Chung ) , 김동명 ( Dong Myung Kim ) , 유형곤 ( Hyeong Gon Yu ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

우리나라 이자율 차익거래 유인과 주식시장 변동성의 연관성에 관한 연구: 2007-2008년 세계 금융위기를 전후하여

오주연 ( Joo Youn Oh ),구형건 ( Hyeng Keun Koo ),현종석 ( Chong Seok Hyun ) 한국금융공학회 2014 금융공학연구 Vol.13 No.3

본 논문은 2007-2008년 세계 금융위기 전후 우리나라 이자율 차익거래 유인과 주식시장 내재변동성의 관련성에 대하여 분석한다. 금융위기 발생 시점인 2007년 7월 이후 이자율 차익거래 유인은 V-KOSPI와 높은 정(+)의 상관관계를 보인다. 이는 국가 신용위험이 이자율 차익거래 유인과 주식시장 내재변동성에 미치는 영향이 커지면서 발생한 것으로 추정된다. 그랜저 인과관계 검정 결과에 따르면 금융위기 이전에는 V-KOSPI와 이자율 차익거래 유인 사이에 선후행성이 나타나지 않으나 금융위기 발생 이후에는 V-KOSPI가 이자율 차익거래 유인을 선행하는 것으로 나타난다. 금융위기 발생 이후 기간에 충격 반응을 분석한 결과에서도 V-KOSPI에 대한 외생적 충격이 이자율 차익거래 유인에 지속적으로 영향을 미치는 것으로 나타난다. 반면에 국가 신용부도스왑 수수료율과 이자율 차익거래 유인 사이의 선후행성은 일관되게 한 쪽 방향으로 형성되지 않는다는 점에서 차이가 난다. 이는 금융시장이 불안한 국면에서는 주식시장 변동성이 신용부도스왑 수수료율에 영향을 미치고, 결과적으로 이자율 차익거래 유인의 변화를 유도한다는 기존의 연구와 일치한다. 본 연구는 2007-2008년 금융위기 발생 이후 우리나라 주식시장 내재변동성과 이자율 차익거래 유인이 상호 연관되어 있음을 실증적으로 보였다는 점에서 의의가 있다. We investigate the relationship between the dollar-based covered interest rate disparity (CIRD, violation of the interest rate parity) and the stock market implied volatility in South Korea before and after the 2007-2008 global financial crisis. Since the advent of the global financial crisis in July 2007, the observed disparity exhibits a high positive correlation with the V-KOSPI. We propose the following explanation: the sovereign credit risk of South Korea had larger effects on the CIRD and on the stock market implied volatility during the crisis than it had had previously, and hence the linkage among them became tighter. The Granger causality test shows that there had been no causality between the V-KOSPI and the CIRD before the crisis, but the V-KOSPI has caused the CIRD since the advent of the crisis. The impulse response analysis also verifies that external impacts to the V-KOSPI consistently have had influences on the CIRD after the crisis. This contrasts to the fact that there has been no clear causality between the Credit Default Swap (CDS) spread of South Korea and the CIRD. The empirical evidence coincides with the extant literature which shows that stock market volatility has a larger influence on credit risk during a crisis period than when the market is normal and the volatility is related to the frequency of interest rate arbitrage opportunities.

전층각막이식술 후 발생한 감염성 각막염의 임상양상 및 위험인자

김미진,오주연,김미금,한상범,이진학,위원량,Mijin Kim,Joo Youn Oh,Mee Kum Kim,Sang Beom Han,Jin Hak Lee,Won Ryang Wee 대한안과학회 2010 대한안과학회지 Vol.51 No.4

Purpose: To report the clinical manifestation, predisposing factors, microbiological profiles and treatment outcome of infectious keratitis following penetrating keratoplasty (PK). Methods: Medical records of the post-PK patients later diagnosed with culture-positive keratitis, between January 2003 and June 2008 at our hospital were retrospectively reviewed. Results: Among 228 eyes of 226 patients who previously had PK, 18 eyes (7.89%) of 16 patients developed microbial keratitis. Fifteen patients had a bacterial infection, of which a Streprococcus species was the most common causative microorganism (6 eyes, 33.3%). Three eyes had fungal infection; one case was co-infected with bacteria. Six eyes (33.3%) presented with a suture-related problem, and sixteen eyes (88.9%) had been using topical glaucoma medications. The suture-related problem and use of glaucoma medication were significantly associated with the development of infectious keratitis (p=0.040 and 0.013, respectively). Remission was achieved in all cases within the mean duration of 2.47 months after treatment initiation. However, visual improvement was not achieved in 11 eyes (68.7%) due to graft opacity. Conclusions: Early identification of predisposing factors and appropriate management at an early stage may prevent the occurrence of graft infection and improve graft survival. J Korean Ophthalmol Soc 2010;51(4):504-509

후천성 면역 결핍증 환자에서 발생한 각결막의 편평세포암 1예

양민규,김보혁,김미금,위원량,오주연,Min Kyu Yang,Bo Hyuk Kim,Mee Kum Kim,Won Ryang Wee,Joo Youn Oh 대한안과학회 2013 대한안과학회지 Vol.54 No.9

Purpose: To describe the clinical and histopathological findings of corneal and conjunctival squamous cell carcinoma (SCC) in a patient with acquired immune deficiency syndrome (AIDS). Case summary: A 45-year-old Korean male who had been diagnosed of AIDS 20 years before presented with vascularized mass in the inferotemporal conjunctiva and in the cornea. The patient underwent an en bloc excisional biopsy of the mass, application of mitomycin C, and repeated cycles of freeze-thaw. Histopathology revealed dysplastic squamous epithelium in the full thickness of epithelial layer. Immunohistochemical staining for proliferation markers showed that the tumor had a high proliferation index: Ki-67 was positive throughout the full epithelial layer, and both p53 and p16 were positive. The patient had an adjuvant chemotherapy with topical interferon alpha 2b (IFNα 2b) for 8 months after surgery. Conclusions: Given the high proliferation index of the tumor in this patient, close observation and combined adjuvant chemotherapy will be required to prevent recurrence in a patient with AIDS.

전층각막이식술을 받은 5세 이하 환아들의 수술 성적

김용우,최혁진,김미금,위원량,유영석,오주연.Yong Woo Kim. MD. Hyuk Jin Choi. MD.. Mee Kum Kim. MD. Won Ryang Wee. MD.Young Suk Yu. MD. Joo Youn Oh. MD 대한안과학회 2013 대한안과학회지 Vol.54 No.5

Purpose: To investigate the clinical outcomes of primary pediatric keratoplasty. Methods: Records of patients who underwent penetrating keratoplasty at the age of 5 years or younger were retrospectively reviewed. The survival rates of corneal grafts, postoperative complications, and causes of graft failure were evaluated. Results: A total of 31 penetrating keratoplasties were performed in 29 patients, two of which were bilateral. The mean follow- up period was 78.72 ± 8.94 months. The overall graft survival rate was 51.61%. The graft survival rate was 77.4% at 6 months, 61.3% at 12 months, 57.5% at 2 years, and 49.5% at 5 years after the surgery (the median survival time, 39.2 months). The main surgical indications included sclerocornea (35.5%), followed by Peter’s anomaly (25.8%) and congenital glaucoma (9.7%). There were significant differences in graft survival time among the surgical indications, of which sclerocornea was the worst (p = 0.003). The main cause of graft failure was rejection (46.7%), followed by infection (26.7%) and primary endothelial decompensation (20%). When patients were sub-grouped according to age (under 12 months, between 12 to 48 months, and over 48 months), there was significant difference in graft survival time (p = 0.037) but not in overall graft survival rate (p = 0.154). Graft rejection occurred more frequently in patients between 12 to 48 months of age compared to other age groups (p = 0.016). Three out of 13 graft infections occurred in patients under 12 months of age. Conclusions: The type of disease causing corneal opacity was a significant factor affecting the clinical outcomes of penetrating keratoplasty in children.

면역억제제를 복용 중인 환자에서 안구표면 편평상피세포암의 안구 내 침범 1예

박은우(Eu Noo Bak),류진숙(Jin Suk Ryu),곽상인(Sang In Khwarg),오주연(Joo Youn Oh) 대한안과학회 2016 대한안과학회지 Vol.57 No.3

목적: 면역억제제를 복용 중인 환자에서 발생한 안구표면 편평상피세포암의 안구 내 침범에 대한 임상적, 조직학적 소견과 치료 경과에 대해 보고하고자 한다. 증례요약: 신장이식 후 17년간 면역억제제를 복용 중인 59세 남자 환자가 재발하는 우안 결막의 하얀 병변을 주소로 내원하였다. 병변의 절제적 생검 후 절제부위에 mitomycin C 점적 및 양막이식술을 시행하였다. 조직학적 검사상 편평상피세포암으로 확인되었다. 당시 시행한 안와 전산화 단층촬영검사상 특이소견은 관찰되지 않았다. 술 후 6개월간 Interferon alpha 2b 안약을 점안하였다. 술후 1년째 우안 결막 병변이 재발하여 절제적 생검과 mitomycin C 점적, 반복적 냉응고요법, 양막이식술을 시행하였다. 같이 시행한 안와 전산화 단층촬영검사에서 우안 내측에 1.9 cm의 고밀도 종괴가 관찰되어 편평상피세포암의 안구 내 침범으로 진단하고 우안안와내용물제거술을 시행하였고, 조직학적 검사상 편평상피세포암으로 확인되었다. 결론: 면역억제제 복용 환자에서 발생한 안구표면 편평상피세포암은 빠르게 다른 부위로 침범할 수 있음을 고려할 때 수술적 완전절제 후에도 적극적인 경과 관찰이 필요하다. Purpose: To report a case of ocular surface squamous cell carcinoma with intraorbital extension in a patient with renal transplantation and long-term immunosuppressive therapy. Case summary: A 59-year-old Korean male presented with a whitish mass in the medial limbus and conjunctiva of the right eye. The patient had undergone renal transplantation 17 years prior due to lupus nephritis and was on systemic immunosuppression with daily prednisolone (10 mg), tacrolimus (5 mg), and mycophenolate sodium (720 mg). The complete excision of the mass was performed and mitomycin C application and amniotic membrane transplantation on the excised area were combined. Histopathological examination revealed the mass was squamous cell carcinoma. There were no abnormal findings on the orbit computed tomography (CT). The patient was additionally treated with topical interferon alpha 2b 6 months postoperatively. One year later, a mass recurred at the same site in the right eye. The complete excision of the mass, mitomycin C application, cryotherapy, and amniotic membrane transplantation were performed. Orbit CT showed a 1.9 cm-sized intraorbital mass involving the medial rectus of the right eye. The orbital exenteration was performed and the intraorbital mass was histologically proven to be squamous cell carcinoma. Conclusions: Ocular surface squamous neoplasia in patients with renal transplantation and long-term immunosuppressive therapy should be monitored closely for the possibility of orbital invasion.

홈 에너지 플랫폼을 위한 네트워크 구조 설계

박경민(Kyungmin Park),함동욱(Dong-Wook Ham),양효식(Hyo-Sik Yang),오주연(Joo-Youn Oh) 대한전기학회 2013 대한전기학회 학술대회 논문집 Vol.2013 No.7