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영릉향으로부터 분리된 Foenumoside B의 부위별 함량비교 연구
엄영란,목소연,신재혁,김슬기,조병헌,조용백 한국생약학회 2014 생약학회지 Vol.45 No.1
Lysimachia foenum-graecum (LF) has been used for home remedy of common cold and headache in China. Foenumoside B from LF has been reported for anti-obesity effects. We used foenumoside B as a marker for content evaluation of different parts of LF. Ethanol extract of LF was used for isolation of foenumoside B and purified further by column chromatography. The structure was identified as foenumoside B by interpretation of spectroscopic analysis, including 1H-, 13C-NMR and FT-ICR-MS. High-performance liquid chromatography (HPLC) method was used to compare the quantitative level of foenumoside B in different parts of LF. Foenumoside B contents in the leaf, stem, and aerial part showed significant differences. Contents of foenumoside B was detected highly in the leaf extracts. The results would be useful for efficient extraction of foenumoside B in LF.
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엄영란 여성건강간호학회 1996 여성건강간호학회지 Vol.2 No.2
Over one million cases of the induced abortion have been conducted annually in Korea. Among those cases, most of all were illegally done, but this has not been addressed in the literature. While Korean Nurse Association Code of Ethics presents the respect for life as one of the basic ideology, it was not dealt enough in nursing education. The purposes of the study were to activate the debate on the issues related to an induced abortion ; to introduce the related ethical theories ; and to seek the solution of the ethical problems, which will eventually result in establishing the morality of nursing practice. The ethical theories of an induced abortion have traditionally addressed two extreme perspectives ; the conservatives who emphasize the sanctity of human life and the right of life that will never ethically allow the killing fetus ; and the liberalists who insist the right to choice for women to control their body. Since these extreme theories has not been helpful to solve the ethical problems, the recent trend is leading to the modified theories both from conservative and liberal perspectives. The examples of the theories are the potentiality of fetus (Singer, 1993), the obligation of women to serve their body to fetus (Held, 1987), the Replacement theory (Callahan, 1987), and the Principle of Caring (Gilligan, 1982). The study conducted the indepth interviews with 17 women who experienced the induced abortion and the 6 cases were selected to be analyzed. The cases were analyzed and interpreted by using an integrated case method, which was combined of the New Casuisty (Jonsen & Toulmin, 1988 ; Jonsen, 1991) and the Specified Principlism (Richardson, 1990 ; Degrazia, 1992). The result of analysis revealed three types of ethical problems ; (1) the responsibility of taking care of the baby to be born (2) the fear for the condition of the fetus, and (3) the choice of induced abortion as the method of birth control. The findings also revealed the related ethical principles for various situations ; the principle of caring was used for choosing an induced abortion by the subjects ; the principles of the potentiality of fetus and the obligation of women to serve their body were for the consideration for the life of fetus ; and the principle of replacement was utilized for the right to choice for women. The ethical principles related to an induced abortion introduced in the study provided the way to solve the moral problems by applying to the clinical situations for nurses. The study also revealed the possibility of modifying the current ethical theories from the method of applying the principles to the various situations in the study. The modified theories would be more useful to guide the clinical practice with similar ethical problems.
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간호사의 간호 제공 의무와 말기 환자의 간호 거부에 관련된 윤리 문제에 관한 연구
엄영란,홍여신 한국간호과학회 1994 Journal of Korean Academy of Nursing Vol.22 No.4
Respect for human life and respect for human dignity are two basic values to which organized nursing has urged its members to adhere in their service to mankind. Thus it is the nurses’ duty to provide health care in support of sustenance of life and to pay respect for the patient’s right to dignity. In practice, however, nurses may experience dilemmas between these duties much due to the de velopment of modern advanced techniques. These dilemmas have become more complex and difficult to resolve. Nurses are often faced with situations in which the terminally ill refuse professional care, posing serious conflicts between respect for human life and respect for human rights to self-determination. In such cases, resolution of the problem is not a simple matter, thus requires intensive study into the ethical questions related to the situation. The purpose of this study was to identify ethical problems that nurses experience in caring for terminally ill patients and explore the ways to the resolution of problems within the context of the situations. The methodology used for the study was a case study method which ‘New Casuistry’ proposed by Jonsen & Toulmin(1988) and the ‘Specified Principlism’ proposed by Degrazia(1992) as an alternative to old deductive and intuitive method. Cases were developed through semistructured indepth interviews according to the casutistry method. A total of seven nurses were interviewd who were caring for therminally ill patients. Four cases out of a total 14 cases were related to the topic. Through the case analysis it became evident that nurses appreciated other values more often than respect for the patient’s right to self-determination. These other values were convenience and efficiency in nursing practice in case 1, preservation of life above all other values in case 2, provision of nursing care to fulfill the nurse’s professional obligation at most in case 3, and respect for the family’s demand against the patient’s wish in case 4. This study showed that the most important ethical problems were conflict between respect for the patient’s right to self-determination and sustenance of life for the fulfillment of professional obligation. For this problem, benefit /burden analysis from the perspective of the patient and family for the promotion of patient’s wellbeing may be a way to resolve the conflict. Further, through these analysis it was shown that physicians’ and families’ opinions dominated in the decision - making and the opinions of nurses’ and patients’ tended not to be reflected. Thus the patient's right to his or her care was not readily respected. To solve this problem. nurses should make efforts to communicate reciprocally with their patients, family members and physicians in an effort to respect for their patient’s rights to life and diginity from the point of view and values of the patient. It is also important that nurses provide good basic nursing care up to the time of death regardless of decisions about providing or not aggressive treat-ment for chronically and terminally ill patients.
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엄영란,이정임,이진혁,김해진,예성수,서영완,Um, Young-Ran,Lee, Jung-Im,Lee, Jin-Hyeok,Kim, Hae-Jin,Yea, Sung-Su,Seo, Young-Wan 대한화학회 2010 대한화학회지 Vol.54 No.6
우리나라 동해안에 서식하는 염생식물인 갯방풍으로부터 2개의 polyacetylene 화합물인 falcarindiol(1)과 falcarinol(2), 4개의 coumarin 화합물인 bergapten(3), xanthotoxin(4), umbelliferone(5), scopoletin(6) 및 1개의 sesquiterpene 화합물인 $(5\beta,10\alpha)$-lasidiol angelate(7)가 분리되었다. 이들 화합물 중 scopoletin(6)과 $(5\beta,10\alpha)$-Lasidiol angelate(7)는 갯방풍으로부터 처음 분리되어진 것이다. 분리된 화합물의 구조결정은 $^1H$ COSY, HMQC 그리고 HMBC와 같은 2D NMR 분광학적 실험과 문헌에 보고 된 값을 비교하여 이루어졌다. Two polyacetylenes (1 and 2), four coumarins (3-6), and one sesquiterpene (7) were isolated from the halophyte Glehnia littoralis. Particularly, compound 6 and 7 were isolated for the first time from Glehnia littoralis. Their chemical structures have been determined by extensive 2-D NMR experiments such as $^1H$, COSY, HMQC and HMBC and by comparison with the reported data in the literature.
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엄영란 中央醫學社 1990 中央醫學 Vol.55 No.7
People often claim their own rights but may not be deeply concerned about what those rights are or how they may claim them. Furthermore they may not be aware of other's rights and the interrelationships among various rights. Recently, in Korea, many people have begun to claim their rights. But the nature of those rights and methods of securing them have been scarcely examined or reflected upon. This paper examined the concept of human rights, the characteristics of patients' and nurses' rights, and obligations through a theoretical conceptual analysis. From the 17th century, philosophers began to be concerned about the concept of human rights. Until then they had emphsized only duties to their king or God. But awareness of personal dignity gave rise to the concept of human rights. Thereafter they sutdied the basis for rights-and the attributes of rights. This paper first examined the grounds for human rights? Accodring to natural law theorists, the ground is the natural law which is prior to positive laws and can be regarded as the rational participation in the eternal law of God. Utilitarians assert the principle of utility which menas "the greatest happiness of the greatest number". And those who lay stress on the value of human life emphasize "the fact itself that one is human". But as yet there is no consensus about the ground and nature of human rights. Philosophers have also studied the relation between rights and duties or obligations. According to the doctrine of the "logical correlation" of obligations and rights, a right implies that someone else has an obligation to act in certain ways. Mill usefully approached this problem by employing the distinction between duties of perfect obligation and duties of imperfect obligation. And Feinberg writes, "A positive right is a right to another person's positive actions; a negative right is a right to another person's omissions or forbearances. This study then analysed the rights of patients and nurses. Patients' rights have following characteristics. First, all patients equally have the right to quality health care. These may be negative rights for their health care professional, but positive rights for society and the nation. Second, patients have the right to be treated as a person. Nurses have the right to practice autonomously based on their own knowledge and skills without interference. This menas that other professions should not inhibit them from acquiring this right. And given the importnace of nurses' role in society but it's oppressive history, nurses might claim this as a positive right for society and the nation. Finally the paper examined nurses' professional resposibilities. Through the enhancement of their scientific knowledge and skills, nurses can fulfill the obligation for patient's rights to independent and quality nursing care. Nurses can enhance their realization of their professional roels, through further examination and analysis of their patient's right and their own rights and obligations.
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