원발성 척수종양의 임상적 고찰 : MRI소견과 병리조직학적 결과를 중심으로 Basis of MR Diagnosis and Histopathologic Diagnosis

양국희,박형천 최신의학사 2000 最新醫學 Vol.43 No.9-10

해면 정맥동에 발생한 가성 임파종 : 증례보고 Case Report

양국희,이규성,김태승,김동익 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.11

A case of pseudolymphoma involving the cavernous sinus in a 38-year-old male patient is reported. The patient was admitted because of intermittent diplopia and left side facial sensory change. The tumor was well demarcated, homogeneously enhancing mass in the left side cavernous sinus on MRI. The histopathological findings showed diffuse and dense infiltration of lymphocytes in connective tissue stroma without forming lymphoid follicle or germinal center and the infiltrating lymphocytes were well differentiated and matured. We report a rare case of pseudolymphoma arising in the cavernous sinus, which revealed polyclonal differentiation of lymphocytes confirmed the diagnosis of pseudolymphoma.

비합리적 도박신념 및 타인의 승리에 대한 정보가 도박행동에 미치는 영향

양국희,장문선,곽호완,구본훈 한국건강심리학회 2012 한국심리학회지 건강 Vol.17 No.2

비합리적 도박신념은 도박을 시작하거나 도박행위를 지속하게 하는 주요한 요인이다. 본 연구에서는 대학생들을 대상으로 하여 비합리적 도박신념이 높을 경우, 다른 사람의 승리에 대한 정보가 주어질 때 도박행동이 더욱 촉진될 것으로 보고 이를 실험적으로 검증하고자 하였다. 구체적으로, 505명의 대학생들에게 비합리적 도박신념 척도를 실시한 후, 이들을 비합리적 도박신념 척도 점수가 높거나 낮은 집단으로 분류하였다. 이들 집단을 타인의 승리에 대한 정보가 제시되거나 제시되지 않는 실험 조건에 무선적으로 배정하였다. 실험 결과, 타인의 승리에 대한 정보가 제시된 조건에서는 비합리적 도박 신념이 높은 집단이 낮은 집단에 비해 유의하게 게임 횟수, 베팅금액이 많았고, 게임시간이 더 긴 것으로 확인되었다. 그러나 타인의 승리에 대한 정보가 제시되지 않은 조건에서는 두 집단 간에 유의한 차이가 없었다. 이러한 결과들을 종합하여 결과의 시사점과 제한점에 대해 논의하였다. The irrational gambling belief has been considered a critical factor which makes people develop or maintain gambling behavior. This study aimed to investigate the effects of irrational gambling belief and reports of wins on gambling behavior. For this research, 505 university students were asked to answer the Gambling Belief Questionnaire (GBQ) and were divided into two groups according to level of irrational gambling belief representing the possible combinations of GBQ. In the experimental study, the participants in each group were assigned to one of two experimental conditions, according to existence of reports of wins. The results showed that there was significant interaction between irrational gambling belief and reports of wins on gamble. Finally, the limitations and suggestion for further research were discussed.

뇌동맥류 파열 환자에서 조기 수술 대상 선택 : 10년간 1026 치험예를 바탕으로한 분석 Based on 10-year Experience with 1026 Patients

양국희,박현선,신용삼,주진양,허승곤,이규창 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.11

The purpose of this study was to set the guidelines for selection of patients to do early surgery in ruptured intracranial aneurysm. We assessed 706 patients with single rupture and without large hematoma, who underwent aneurysm surgery from 1985 to 1995. The male and female ratio was 1 : 1.5 Among the 706 patients, early surgery was performed in 214 cases. The results of early surgery were good in 193 cases(90 2%). fair in 13 cases(6.0%), poor in 1 case(0.5%) and dead in 7 cases(3.3%). The rate of dead outcome in the early surgery group was higher compared to other timing groups. The Fisher group 1, 2 and 3 revealed good outcome in early surgery group ; 92.6%, 96.3%, 88.8% respectively. The incidence of delayed ischemic deficits(DID) of early surgery group was same as other groups. However, in Fisher group 3, the incidence of DID was significantly low. 32. 5%, in early surgery group. It is suggested that the criteria of selection of early surgery in patients with ruptured intracranial aneurysm would include as follows : 1) patients with good clinical grade. 2) poor grade patients with marked irritability. acute hydrocephalus, and poorly controlled hypertension, 3) none-complex aneurysm requiring less brain retraction, dissection and brief temporary clipping. 4) age under 60 or over 60 with good physical status, and 5) Fisher group 3 requiring cisternal larvage and anticipated triple-H therapy.

뇌간에 발생한 신경절교종

신명주,양국희,김태성,최중언 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.32 No.3

Ganglioglioma comprises about 2% of all intracranial neoplasm, however, it is rarely originated from the brain stem. We report a case of ganglioglioma arising from the brain stem. A 15-year-old girl presented with gait disturbance and dysarthria. Magnetic resonance image revealed a high signal intensity mass with cystic cavities in the right cerebellum and the brain stem. The patient underwent subtotal resection and microscopic examination revealed a ganglioglioma. It is suggested that ganglioglioma should be included in the differential diagnosis of posterior fossa tumors, even located in the brain stem. Key words:Ganglioglioma;Brain stem;Magnetic resonance imaging.

The Surgical Effect of Callosotomy in the Treatment of Intractable Seizure

김동석,양국희,김태곤,장종희,장진우,최중언,이병인 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.2

We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.

복합 부분 발작에서 MRI상 가역적 국소 변화 : 증례보고 A case Report

이동엽,양국희,최중언 최신의학사 2003 最新醫學 Vol.46 No.11-12

Slit Ventricle Syndrome in Children : Clinical Presentation and Treatment

신범식,양국희,김동석,최중언,Shin, Beom-Sik,Yang, Kook-Hee,Kim, Dong-Seok,Choi, Joong-Uhn The Korean Neurosurgical Society 2001 Journal of Korean neurosurgical society Vol.30 No.2

틈새뇌실증후군은 수두증으로 션트술을 시행받은 환아에서 CT나 MRI소견상 틈새처럼 좁은 뇌실을 가지고 있으면서 간헐적으로 두통, 구토 또는 의식장애등이 동반되는 질환이다. 1986년부터 1996년까지 총 821명의 환자가 수두증으로 션트술을 시행받았다. 이 환자들의 수두증의 원인은 뇌종양(140명), 출혈(62명), 정상압수두증(64명), 뇌수막염(58명), 외상(54명), 선천성(48명), 뇌낭미충증(31명), 그리고 이유를 알 수 없었던 경우가 364명으로 나타났다. 평균 추적 관찰 기간은 68개월이었으며 총 232명에서 재수술을 시행하였으며 1인당 1.28회의 재수술율을 보였다. 이들중 틈새뇌실 증후군은 6예로 0.7%였다. 틈새뇌실증후군 대부분의 환자는 영아기에 수술을 시행받았다. 처음 수술로부터 틈새뇌실증후군이 발생하기까지의 기간은 4~8년으로 평균 6년후 틈새뇌실증후군이 발생하였다. 동위원소 검사상 6예에서 션트의 기능은 모두 정상이었다. 증상이 경미한 2명의 환자에서는 보존적 치료를 시행하였는데 치료후 증상의 호전을 보였다. 이 환자들은 뇌압측정을 시행하지 않았다. 6명중 1명은 뇌압 측정시 높게 나타나 기존과 같은 압력밸브를 이용하여 재수술을 시행하였다. 3명의 환자는 낮은 뇌압을 보여 안티사이펀밸브나 기존보다 높은 압력의 밸브를 이용하여 재수술을 시행하였다. 틈새뇌실증후군의 치료는 첫째, 증후군의 양상을 정확하게 판단하여, 둘째, 증상을 완화시킬 수 있는 방향으로 치료방침을 설정해야 할 것으로 생각되었다. The term slit ventricle syndrome(SVS) refers to an episodic occurrence of headache, vomiting, and possibly some degree of impaired consciousness in shunted hydrocephalic children in whom slit-like ventricles are seen on CT scan or MRI. Authors present 6 cases with SVS who were treated at our institute for last 10 years. From 1986 to 1996, 821 patients underwent shunt surgery for hydrocephalus. The etiology of hydrocephalus included brain tumor(140 patients), post-hemorrhagic(62 patients), idiopathic normotensive hydrocephalus(64 patients), post-meningitic( 58 patients), post-traumatic(54 patients), congenital(48 patients), neurocysticercosis(31 patients), and unknown etiology(364 patients). During the mean follow-up duration of 68 months, 232 shunt revisions were performed by a revision rate of 1.28 per patient. The incidence of SVS was 0.7%(6 patients). Most of them have been operated on in infancy. Time interval from the first operation to the development of slit-ventricle syndrome ranged from 4 to 8 years, the mean was 6 years. Shuntogram showed patent shunt in all patients. Two patients with less severe clinical symptoms improved with conservative treatment. These patients were not measured ICP because of good hospital course. One patient showed high ICP and needed only revision with same pressure valve as previous shunt. Low ICP was noted in 3 patients. Pressure augmentation using an anti-siphon device(ASD) or upgrading valve system were necessary in these patients. The authors stress that determining type of SVS is the first step in treatment planning and that the best treatment is a strategy aimed at resolving the specific type of SVS responsible for the symptoms.

원발성 두개강내 혈관 내피세포종- 증 례 보 고 -

한인보,양국희,김동석,최중언,김태승 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

Hemangioendothelioma is a recently described uncommon vascular neoplasm, characterized by epithelioid tumor cells and borderline biologic behavior. Its histological features and clinical behavior are intermediate between those of hemangioma and angiosarcoma. Its four principal sites of occurrence are the soft tissue, liver, lung and bone. Its intracranial occurrence is extreamly rare. We report a case of primary cerebral hemangioendothelioma in a 29-year-old male patient. Key words:Hemangioendothelioma;Epitheloid cell;Intracranial.

두개인두종: 재발 관계 인자

이성,양국희,김동석,최중언 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.32 No.3

Objective:The authors present a retrospective analysis of the long-term recurrence rate for the 79 craniopharyngima patients surgically treated between Jan 1989 and Dec 1999. Methods:Tumor recurrence rates were analysed with respect to age of patients, symptom duration, tumor size, localization of tumor, morphology of tumor, the extent of surgical resection, pathologic diagnosis and the other treatment modalities. Results:For 79 patients, with a mean follow-up period of 5 years, the overall recurrence rate was 29%. Factors associated with decreased risk of recurrence was gross total tumor resection(p=0.01). Subtotal resection was associated with increased risk of tumor recurrence. The adjuvant radiation therapy was revealed efficient not in decreasing recurrence rate but in the delay of tumor recurrence time(p=0.05). There were no differences in recurrence rates for other factors. Conclusion:A rigorous evaluation of recurrence for craniopharyngima must consider the extent of resection, as judged by postoperative imaging. Adjuvant radiation therapy or Gamma knife surgery could be the effective treatment modalities. Key words:Craniopharyngioma;Recurrence rate;Surgery;Postoperative imaging;Radiation therapy.