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대강활탕(大羌活湯)이 동물모델의 Carrageenan 유발 관절염에 미치는 영향
안중혁 ( Jung Hyeok An ),이명종 ( Myeong Jong Lee ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.2
Objectives : This study was designed to elucidate the effects of Daeganghwal-tang(Daqianghuoshang) on the carrageenan-induced arthritis. Methods : Each of the 10 rats were classified into normal, control, sample group. Arthritis was induced by injecting 0.1㎖ of 1% carrageenan per rat in sample and control group. Daeganghwal-tang(Daqianghuoshang) was administered to sample group and normal saline was administered to normal and control group and then CRP, WBC, Neutrophil, Lymphocyte, Monocyte, Eosinophil, RBC, Platelets, Hematocrit, Hemoglobin, MCV, MCH, MCHC, SGOT, SGPT, LDH were measured. Results : In the sample group, the loss of body weight, edema rate of paw, skin temperature in edema, WBC, neutrophil, hematocrit, Hb, MCV, SGOT, LDH were significantly decreased as compared with those of control group. In the sample group, rectal temperature, lymphocytel, eosinophil, MCHC were significantly increased as compared with that of control group. Conclusions : According to the above results, it can be concluded Daeganghwal-tang(Daqianghuoshang) showed the treatment effects on the artificial arthritis resulted from carageenan in rats and it is suggested that more interest and study in the security for the clinical use were needed.
동의보감(東醫寶鑑) 요문(腰門)의 요통처방(腰痛處方)에 대(對)한 분석(分析)
안중혁 ( Jung Hyeok An ),이명종 ( Myung Jong Lee ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.1
Objectives: This analysis of prescription used for low back pain in the Yomun(腰門) chapter of 《Donguibogam(東醫寶鑑); The Precious Mirror of Oriental Medicine》is designed to be helpful to practical use of clinics. Methods : Prescriptions used for low back pain in the Yomun(腰門) chapter of 《Donguibogam(東醫寶鑑)》were classified and analyzed according to the frequency of prescriptions and the characteristics of each herbs in prescriptions(efficacy, used frequency, related organs etc.). Results and conclusions : After analysis, we obtained the following results : 1. The causes of low back pain are mainly eohyeol(瘀血), yangheo(陽虛), punghanseub(風寒濕). In care of low back pain, I suppose more efficiency that if Angelica gigas NAKAI(當歸) Cnidium officinale MAKINO(川芎) Prunus persica BATSCH(桃仁) is added when the cause is eohyeol(瘀血), or if Psoralea corylifolia L.(破古紙), Cinnamomum cassia PRESL(肉桂), Foeniculum vulgare MILL(茴香), Eucommia ulmoides OLIV.(杜沖), Citrus unshiu MARKOVICH(陳皮) are added when the cause is yangheo(陽 虛), or if Phellodendron amurense RUPR.(黃柏), Notopterygium incisum TING(羌活), Atractylodes Japonica KOIDZ.(蒼朮) are added when the cause is punghanseub(風寒濕).