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      • KCI등재

        망막분지정맥폐쇄에서 황반부종 치료로 유리체강내 베바시주맙 주입술의 장기 효과

        안성민,이수정,박정민,Seong Min Ahn,Soo Jung Lee,Jung Min Park 대한안과학회 2014 대한안과학회지 Vol.55 No.3

        Purpose: To evaluate the long-term results of intravitreal bevacizumab injection for macular edema secondary to branch retinal vein occlusion (BRVO). Methods: Fifty-six eyes with macular edema secondary to BRVO were treated with intravitreal bevacizumab injection. They were classified into two groups, one group that received three initial intravitreal bevacizumab loadings at monthly intervals and a second group that received only one initial injection. In the two groups, additive injection was performed at recurrence. The best corrected visual acuity (BCVA), central macular thickness (CMT) and retinal ischemic change was analyzed for more than 12 months postoperatively. Results: After 12 months of follow-up, mean BCVA improved and mean CMT reduced significantly in both groups (p< 0.05). However, the range of BCVA improvement and CMT reduction was wider in the three-injection group than in the single-injection group. Fluorescein angiography revealed posterior retinal ischemic changes; bevacizumab didn't seem to aggravate the ischemic change. No drug-related ocular or systemic side effects were observed in the follow-up period after intravitreal bevacizumab treatment except subconjunctival hemorrhage and a mild increase of intraocular pressure. Conclusions: In patients with macular edema secondary to BRVO, intravitreal bevacizumab injection was a safe and effective treatment, and a more significant visual improvement and reduction of macular edema was achieved after three initial loadings rather than after a single injection. J Korean Ophthalmol Soc 2014;55(3):379-386

      • KCI등재

        전신성 홍반성 루푸스에서 병발한 시신경척수염 1예

        안성민,김상수,Seong Min Ahn,Sang Soo Kim 대한안과학회 2013 대한안과학회지 Vol.54 No.9

        Purpose: We present a case of a patient with coexisting neuromyelitis optica and systemic lupus erythematosus (SLE). Case summary: A 26-year-old female was hospitalized in our medical center due to decreased visual acuity in her left eye; she had a history of gastric ulcers and herpes zoster infection. Steroid treatment was started under suspicion of optic neuritis, and she was diagnosed with SLE. After treatment, her vision improved, but eleven months later she was hospitalized with paresthesia on the abdomen and left flank progressing to the lower extremities. Spinal MRI showed transverse myelitis, suggesting multiple sclerosis. Fifteen months later, the patient was hospitalized due to decreased visual acuity and ocular pain in the right eye. Her vision was improved by steroid therapy. However, optic neuritis recurred in the right eye after five weeks, thus azathioprine was added to the treatment. Anti-aquaporin-4 Ab test was conducted based on the suspicion of neuromyelitis optica, and the serum was positive for anti-aquaporin-4 Ab (NMO-IgG). The patient was hospitalized again due to paraplegia after three months. Coexistence of neuromyelitis optica was verified because spinal MRI showed longitudinally extensive transverse myelitis. The symptoms were improved by high doses of steroids, a series of plasmaphereses, and rituximab. Optic neuritis was repeated in the right eye and the symptoms were improved with high doses of steroids. Myelitis recurred later and the symptoms improved with high doses of steroids and a series of plasmaphereses. Conclusions: Coexisting neuromyelitis optica should be considered in cases with relapsing events which have transverse myelitis without cranial lesions in autoimmune diseases such as SLE.

      • KCI등재

        거대각막증에서의 백내장 적출 및 인공수정체 삽입술

        안성민,박홍재,이수정,박정민,Seong Min Ahn,MD,Hong Jae Park,MD,Soo Jung Lee,MD,PhD,Jung Min Park,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.1

        Purpose: To report a case that underwent successful centration of intraocular lens (IOL) and visual acuity improvement after cataract extraction in a megalocornic eye in our medical center. Case summary: A 27-year-old man with bilateral megalocorneas came to our medical center. The patient had progressive loss of vision and floaters in both eyes for 3 months. His horizontal corneal diameter was approximately 14 mm in both eyes. The initial best corrected visual acuity was 0.02 in the right eye and 0.5 in the left eye. There was a white cataract and nuclear sclerotic cataract without lens luxation, respectively. The cataract was extracted from the patient’s right eye after anterior continuous curvilinear capsulorrhexis (CCC), the preloaded custom IOL was inserted in the bag, and pars plana vitrectomy was performed. Two months later, after the cataract was extracted from the left eye, optic capture through a posterior capsule was attempted but converted to anterior capsule (reverse optic capture) because of the posterior CCC’s radial tear, and pars plana vitrectomy performed. The IOL had a 6 mm optic and an overall length of 12.5 mm. The IOL in the right eye was decentrated inferiorly in the bag due to a large capsule diameter, but the IOL captured through the anterior capsule in the left eye had good centration. The best corrected visual acuity of both eyes improved to 0.8 without other complications.

      • KCI등재

        코경유 눈물주머니코안연결술에서 폴리에테르 에스테르 우레탄의 임상적 효과

        안성민,김상수,Seong Min Ahn,Sang Soo Kim 대한안과학회 2012 대한안과학회지 Vol.53 No.6

        Purpose: To evaluate the clinical effect of intraoperative application of polyether ester urethane (Nasopore?) in endonasal dacryocystorhinostomy. Methods: Endonasal dacryocystorhinostomy was performed on 77 eyes diagnosed with nasolacrimal duct obstruction between January 2010 and February 2011. Nasopore? was applied to the newly-formed internal lacrimal opening in the experimental group (41 eyes), and vaseline gauze was applied in the control group (36 eyes). For the evaluation of clinical effects regarding postoperative adhesion and stenosis of the internal lacrimal opening, subjective symptom improvement, lacrimal irrigation tests, and endoscopic examinations were performed at 1 week, 2 weeks, 1 month, 3 months, and 6 months, postoperatively. Results: In subjective symptom improvement and lacrimal irrigation tests, differences between the 2 groups were not statistically significant. In endoscopic findings, the Nasopore? group showed significantly lower severity of adhesion and stenosis of the internal lacrimal opening at 1 week, 2 weeks, and 1 month after operation (p < 0.05). Conclusions: Application of the Nasopore? may effectively reduce initial postoperative adhesion or stenosis of the internal lacrimal opening after endonasal dacryocystorhinostomy and has usefulness as an auxiliary method. J Korean Ophthalmol Soc 2012;53(6):743-748

      • KCI등재
      • KCI등재

        방사선(학)과의 작업종사자와 수시출입자의 교내 실습에 따른 피폭선량에 대한 고찰

        전성민(Seong-Min Jeon),이용기(Yong-Ki Lee),안성민(Sung-Min Ahn) 한국방사선학회 2021 한국방사선학회 논문지 Vol.15 No.3

        본 연구에서는 교내 실습 중 방사선(학)과 에 지정된 방사선작업종사자 및 수시출입자의 피폭 정도를 분석하여 방사선(학)과에 대한 원자력안전법의 방사선 방호에 대한 타당성과 최적화에 대한 기초 연구에 목적을 두었다. 연도별 작업종사자의 평균 피폭선량 2014년과 2016년에 0.01 mSv로 가장 낮은 수치가 나타났으며. 가장 높은 수치는 2018년도로 0.12 mSv이다. 연도별 수시출입자의 평균 피폭선량은 2018년 0.013 mSv로 가장 낮은 수치를 보였으며, 2016년 0.022 mSv로 가장 높은 수치가 나타났다. 본 연구를 통하여 방사선발생장치만을 사용하는 대학의 담당교수, 실습 조교 및 방사선(학)과의 학생들은 교내실습 과정에서 받는 연간 피폭선량은 일반인의 선량한도인 1mSv에도 미치지 못하는 수준이다. 그러므로 방사선(학)과 학생들의 피폭선량이 일반인의 선량한도 보다 낮게 나오는 시점에서 현재 원자력안전법의 안전규제는 과도한 규제라고 판단된다. 따라서 현재의 원자력안전법에서 방사선 발생장치의 규정을 개정하거나 대학의 재학생에 대한 방사선안전관리 체계를 수정하는 것은 필요하다고 사료된다. In this study, the purpose of this study was to analyze the degree of exposure of radiation workers assigned to the Department of Radiology and frequent visitors during on-campus practice, and to conduct a basic study on the feasibility and optimization of the radiation protection of the Nuclear Safety Act for the Department of Radiology. . The average exposure dose of occupational workers by year was 0.01 mSv, the lowest in 2014 and 2016. The highest figure was 0.12 mSv in 2018. The average exposure dose of frequent visitors by year was the lowest at 0.013 mSv in 2018, and the highest at 0.022 mSv in 2016. According to this study, the annual exposure dose received by professors, practical assistants, and students in the department of radiology (department) who use only radiation generators in the course of in-school practice is less than 1 mSv, which is the dose limit for the general public. Therefore, at the time when the radiation dose of students in the Department of Radiology is lower than the dose limit of the general public, the current safety regulation of the Nuclear Safety law is judged to be excessive regulation. Therefore, it is considered necessary to revise the regulations for radiation generators in the current Nuclear Safety law or to revise the radiation safety management system for university students.

      • KCI등재
      • KCI등재

        심장 전기생리학 검사 시 조건 변화에 따른 환자 피폭 선량 평가

        고성빈(Seong-Bhin Koh),안성민(Sung-Min Ahn) 대한방사선과학회(구 대한방사선기술학회) 2023 방사선기술과학 Vol.46 No.6

        This study used a adult absorption dose phantom (CIRS model 701-G, USA) made of human equivalent material and the vascular imaging equipment Allura Xper FD 20 (Philips, Netherlands). Optically stimulated luminescent dosimeters (OSLD) were inserted into the anatomical positions corresponding to each organ, and the exposure dose was measured. Dose area product (DAP) and air kerma (AK) measured by the dose meter in the equipment were compared. Continuous imaging was performed at two angles for a total of 20 minutes, with a frame per seconds of 3.75 and 7.5 fps and an FOV of 42cm, 37cm, and 31cm, respectively, under the conditions of fluoflavor I, II, and III, each selected for 5 repetitions. This study was found that selecting a lower fps was the most effective way to reduce patient exposure dose, and adjusting the fluoflavor was a good alternative method for reducing patient exposure dose at high fps. Therefore the method of condition change with the greatest dose reduction effect is to set the minimum FPS and can reduce patient exposure dose according to geometric conditions and fluoflavor characteristics.

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