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- 저자 : 심찬섭(Chan Sup Shi (검색결과 2 건)
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공복 및 식후 장기간 경피경간적 Oddi 괄약근 내압검사
홍수진(Su Jin Hong),이남수(Nam Su Lee),주재학(Jae Hak Joo),조영덕(Young Deok Cho),김진오(Jin Oh Kim),봉형근(Hyung Keun Bong),이준성(Joon Seong Lee),이문성(Moon Sung Lee),김연수(Yun Soo Kim),황성규(Seong Gyu Hwang),심찬섭(Chan Sup Shi 대한소화기학회 1995 대한소화기학회지 Vol.27 No.4
N/A Background/Aims: The short-term perendoscopic manometry of the sphincter of Oddi(SO) may not be representative of overall SO motility. In an attempt to overcomc this limitation, we performed SO manometry using a motility catheter placed via a percutaneous transhepatic biliary drainage catheter in patients with intrahepatic duct stones who had undergone percutaneous transhepatic cholangioscopic lithotripsy. Methods: Long-term recording of percutaneous transhepatic manometry of SO(PTMSO) were performed to 15 of 19 patients, during fasting and after feeding. Results: The mean recording time was 90.0 ' 45.0 min(total: 1,628 min) during fasting and 77.0 23. L min(total: 1,156 min) after feeding. The frequency of contractions of SO in basal fasting conditions varied from 0 to 13/min(mean ' SD: 3.2 l.4/min), and high frequency contractions (HFC; frequency 8/min, duration >2 mins) were observed in l 1 patients from a total of 16 occasions without biliary pain. The mean duration of HFCs and mean interval between HFCs were 4.8 ' l.l min and 72.0 12.4 min respectively. The motility of SO was suppressed by food intake for up to 30min after feeding. In 4 patients, antroduodenal manometry via transnasal route and PTMSO was recorded simultaneously with the total recording time of 926 min. The HFCs of SO were recorded 20 times with 4.5 min of mean durations and 46 min of mean intervals. Migrating motor complexes(MMC.) were recorded in the antroduodenum simultaneously. All occasions of HFCs of SO(20) coincided completely with the phase III of the duodenal MMCs. Conclusions: In fasting, HFCs of SO were frequently observed periodically without biliary pain and completely coincided with the phase III of duodenal MMCs. This finding suggests that some cases of HFCs, previously regarded as tachyoddia' in SO dysfunction by using endoscopically placed motility catheter, may not he the true tachyoddia in SO dysfunction. (Korean J Gastroenterol 1995;27:423 432)
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소화성 궤양에서 Helicobacter pylori 박멸의 장기적 효과에 대한 후향적 관찰
홍수진(Su Jin Hong),은수훈(Soo Hoon Eun),정준성(Joon Seong Jung),류권호(Kwon Ho Ryu),차상우(Sang Woo Cha),천갑진(Gab Jin Cheon),김진오(Jin Oh Kim),조주영(Joo Young Cho),이준성(Joon Seong Lee),이문성(Moon Sung Lee),심찬섭(Chan Sup Shi 대한내과학회 2002 대한내과학회지 Vol.63 No.1
목적: 소화성 궤양 환자에 있어 H. pylori 박멸은 재발 억제를 위해 시행되고 있으나 박멸 후 장기간 추적에 대한 국내 보고는 드문 실정이다. 본 연구에서는 소화성 궤양으로 H. pylori 박멸요법을 시행받고 박멸이 확인되었던 환자에서 H. pylori 재감염율, 궤양의 재발을 장기간 고찰하고자 하였다. 방법: 상부소화관 내시경검사상 H. pylori 양성인 소화성 궤양 환자 중 H. pylori 박멸요법을 시행하고 6주 이후에 박멸을 확인한 환자 763명 중 4년간 장기간 추적이 가능했던 환자 32명을 대상으로 상부소화관 내시경검사 소견, 13C-요소호기검사를 통한 H. pylori 감염 여부를 확인하여 기록하였다. 결과: 32명 중 남성은 22명, 여성은 10명이었고, 평균 연령은 51.7세 (29∼69세)였으며 내시경적 진단은 위 궤양 9명, 십이지장 궤양 12명, 위 궤양 및 십이지장 궤양 11명이었다. 4년간의 추적 기간 동안 H. pylori 재감염은 2명에서 있었고, 연간 재감염율은 1.6%였다. 32명의 환자 중 3명에서 궤양의 재발이 있어 9.4%의 재발율을 보였다. 결론: H. pylori의 연간 재감염율은 선진국의 재감염율과 유사한 1.6%였으며, H. pylori 박멸치료는 소화성 궤양의 재발 방지에 효과적인 유용한 치료방법으로 생각된다. Background: Eradication therapy for H. pylori infection is known to decrease the recurrence rate of peptic ulcer disease. The aim of this study was to evaluate longterm effect of H. pylori eradication on the recurrence of peptic ulcer disease and the reinfection rate after treatment in Korea. Methods: Between July 1996 and February 1997, 763 patients who were diagnosed peptic ulcer diseases and H. pylori infection after upper endoscopies in Soonchunhyang university hospital. Among those patients, we reviewed 32 patients who achieved eradication of H. pylori after eradication therapy and could be followed for up to 4 years by 13C-urea breath test or endoscopy. Results: The mean age of the patients was 51.7 years (range: 29∼68). Nine patients had gastric ulcer, 12 had duodenal ulcer and 11 had duodenal and gastric ulcer. An annual reinfection rate of H. pylori was 1.6% in our study. After H. pylori eradication, recurrence of peptic ulcer was detected in three patients (9.4%). Conclusion: In our study, the reinfection rate was similar to rates observed in developed countries. H. pylori eradication was effective for preventing recurrent peptic ulcers.(Korean J Med 63:23-28, 2002)
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