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신태순,윤혜선 대한천식알레르기학회 1989 천식 및 알레르기 Vol.9 No.3
The purpose of this study is to evaluate the relationship between the feeding methods of infants and the development of allergic diseases. This study was done on 15,009 pupils from May to September, 1987. The skin prick test with common three inhalent allergens(house dust, two house dust mites) was performed on 1,044 pupils. The results were as follows.' 1) The feeding methods for the 6 months of life was composed of breast feeding 54.38%, mixed 27.0%, cow's milk 15.72%, soybean, cereals, etc. 2) The feeding methods for the first 2 days of life was composed of breast milk 56.82%, cow's milk 27.57%, mixed 15.16%. 3) the frequency of asthma and asthmatic bronchitis followed by the infant's diet for the first 6 months was 12.7% for breast milk, 14.7% for cows milk,15.1% for mixed, 15.5% for soybean, cereals, etc., and the frequency of atopic dermatitis was 14.9% for breast milk, 15.3% for cows milk, 16.9% for mixed and the frequency of allergic rhinitis was 6.0 for breast milk, 7.3% for cow s milk, S.l% for mixed, and the frequency of allergic conjunctivitis was 2.5% for breast milk, 3. 9% for cows milk, 3.7% for mixed. 4) The frequency of allergic diseases followed by the infants diet for the first 6 months was 28. L% for breast milk, 31.4% for cow's milk, 33.6% for mixed and 31.0% for aoybean, cereala, etc. 5) The frequency of allergic diaeaaes followed by the infant's diet for the firat 2 days was 27.4% for breast mBk, 34.6% for cows milk, and 32.4% for mixed. 6) The first weaning diet was composed of fruits and vegetables 52.9%, cereals 28.94%, egg 12.7%, meat 4.0% and fishes 1.5 9o. 7) The frequency of allergic diseaaes for the first weaning diet was egg 32.9 Yo, fruit and vegetable 31.7%, fiah 28.8%, cereals 27.2%, and meat 26.2%. 8) The incidence of positive skin reactions followed by the infants diet for the first 6 months w'as 23.5% for breast milk, 25.9% for cows milk and 26.3% for mixed.
신태순,이금자,윤혜선 대한천식알레르기학회 1990 천식 및 알레르기 Vol.10 No.3
The purpose of this study is to research the incidence of allergic diseases in primary school children in Seoul by questionaires which were completed by their parents. This study was done on 4,149 of possible 5,00 0 pupils on June, 1989. Thirty five questions were used to elicit informations about the relationship between allergic diseases and factors such as age, sex, home environment, family history, family smokers and feeding history. The skin prick test with common three inhalent allergens(house dust, two house dust mites) was performed on 1,257 pupils. The results were as follows '. 1) 28.1% of the pupils represented a history of allergic diseases which included asthma or asthmatic bronchitis, allergic rhinitis, allergic conjunctivitis or atopic dermatitis. The incidence of allergic diseases was decreased with increased age and boys were more prevalent to allergic diseases than girls. 2) The incidence of each of allergic diseases was 10.1% for asthma or ashtmatic bronchitis, 10.2% for allergic rhinitis, 7.5% for allergic conjunctivitis, 2.4% for atopic dermatitis, 16.4% for urticaria, 31.2% for food allergy, 7.6% for drug allergy and 0.8% for milk allergy. 3) The incidence of allergic diseases in children who lived in apartments was higher than those on private houses, and allergic diseases were more frequently associated with electric, oil and gas for the heating system than the briquet for that. 4) Allergic diseases were frequently associated with the paper for the material of floor than vinyl for that, and more frequently associated with sofa, carpet or bed than without them. 5) Allergic diseases were rnore frequent in children lived in economically high-leveled group. 6) Allergic diseases were more frequent in children born with dystocia or c-section than with normal delivery, and the incidence of allergic diseases was not related to mothers age. 7) The incidence of allergic diseases in children who lived with family smoker was 28.5%, and in those without family smoker was 27.3%. 8) Breast feeding was less frequently associated with allergic diseases than bottle feeding or mixed feeding. 9) The incidence of allergic diseases with respect to the weaning diet was 29.4% for cereals, 28.9% for meat, 27.9% for egg, 27.2% for fruits and vegetable and 24.0% for fishes. 10) The children with positive skin prick test were more frequently associated with allergic diseases than those with negative.
Glycine이 적출 정상 및 자발성 고혈압 백서 대동맥 평활근의 수축성에 미치는 효과
강석한,신태순,고상돈,김기순 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1
Glycine has been known to possess significant cardiovascular effects. Electrophysiological effects of glycine were demonstrated in the rabbit sinus node cells. Recently it was also reported that glycine induced endothelium-dependent contractions in the isolated rabbit aorta. On the other hand, it has been generally agreed that the vascular reactivity was also altered in spontaneously hypertensive rats(SHR). The present study was performed to investigate effects of glycine on the vascular smooth muscle in the 16 week old Wistar-Kyoto rats(WKY) and in the age-matched SHR. The systolic pressures of WKY and SHR were 123.9±9.4mmHg and 198.5±8.5mmHg, respectively. Glycine(10-100mM) produced endothelium-dependent contractions in the isolated aortic rings of both WKY and SHR. At concentration of 50mM glycine increased vascular tension respectively by 60.2±6.9%(percentage to contraction induced by 1×10 M) and 89.4±2.9% in WKY and SHR. After denudation the vascular responmses to 50mM glycine solution were respectively 25.4±1.8 and 34.2±1.4% in WKY and SHR. Also hyperosmolarity provoked vascular contractions. Following superfusion with 370mOsm Krebsmannitol solution which ws equimolar with 50mM glycine solution, vascular tension increased by 24.5±4.7% in both animal groups. The results indicate that glycine may produce endothelium-dependent contractions in the isolated aorta of SHR, and that vascular responses to glycine are more sensitive in SHR.