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90일 이하 발열 환아에게 중증 세균성 감염의 저위험 예측기준의 유용성
신연호,민영기,전우찬,신연호 대한응급의학회 2012 大韓應急醫學會誌 Vol.23 No.6
Purpose: To examine the usefulness of simple and quick criteria for identifying febrile infants younger than 90 days with a low risk for serious bacterial infection (SBI). Methods: We conducted a retrospective study of febrile infants younger than 90 days who visited an emergency department (ED) between July 2010 and June 2011. We reviewed their medical history, physical examination findings,levels of white blood cells (WBC) and C-reactive protein (CRP), blood culture, urinalysis, and an analysis of their cerebrospinal fluid (CSF). Patients who met all the following criteria were considered to have a low risk for SBI: (1) an unremarkable medical history, (2) a good appearance, (3) no focal physical signs of infection, (4) WBC 5,000~15,000/mm3, (5) CRP <2.0 mg/dL, (6) a normal urinalysis, and (7)CSF WBC <25 /mm3 for neonate or <10 /mm3 for infants between 29 days and 90 days. SBI was defined as a positive culture of bacteria from blood, cerebrospinal fluid, or urine. Results: Complete data were available for 493 infants. SBI was documented in 62(12.6%) infants, with 54(11.0%) having a urinary tract infection, 3(0.6%) with bacteremia, 1(0.2%) with bacterial meningitis, and 4(0.8%) with co-infections. The sensitivity and negative predictive value for SBI from the combination of low-risk criteria was 98.4% and 99.6%, respectively. Conclusion: Although low-risk infants must be carefully observed, our criteria for low-risk might be a reliable and useful tool for excluding SBI for febrile young infants in ED.
신연호,강상기,Shin, Yeonho,Kang, Sanggee 한국인터넷방송통신학회 2014 한국인터넷방송통신학회 논문지 Vol.14 No.6
다양한 서비스에 대한 사용자의 욕구를 충족시키고, 주파수를 효율적으로 사용하기 위해서 여러 통신방식을 하나의 플랫폼에서 제공할 필요가 있다. 다양한 통신방식을 수용하는 광대역 무선통신시스템을 구현하기 위해서는 통신시스템 전단부에 반드시 대역가변필터를 사용해야 한다. 본 논문에는 캐비티 공진기의 구조를 갖는 800 MHz ~ 1600 MHz 범위의 대역가변필터의 구현 가능성을 확인하기 위해서 동일한 동작주파수 범위를 갖는 필터뱅크를 설계 및 제작하였다. 필터뱅크는 원하는 동작주파수 범위에서 5개의 대역통과필터로 제작하였고, 제작한 필터뱅크의 삽입손실은 최대 0.326 dB, 대역폭은 37 MHz ~ 84 MHz 그리고 감쇠특성은 대역 가장자리 ${\pm}60MHz$ 지점에서 최소 19.974 dB와 최대 37.812 dB로 측정되었다. In order to satisfy user's requirements of needs for various services and to efficiently use of frequency, a communication system using one platform can support many communication services. Tunable filters must be used in the front end of broadband communication systems which provide and support various communication methods. In this paper we design and implement a filter bank to verify the feasibility of cavity tunable filter with the operation frequency of 800 MHz ~ 1600 MHz. The filter bank is composed of five bandpass filters and each bandpass filter has the same operation frequency band of the tunable filter. The implemented filter bank has the maximum insertion loss of 0.326 dB, the bandwidth of 37 MHz ~ 84 MHz, and the attenuation of minimum 19.974dB and mximum 37.812dB at the band edge ${\pm}60MHz$ over the operating frequency band.
P-452 : Culture of human hair follicular cells and development of in vitro 3D hair growth model
신연호,이두훈,서영권,유보영,송계용,김영진,양은경,박장서,장이섭,박정극 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.2
The recent development of methods for culturing hair follicles in vitro has been proved to be an important tool to investigate many aspects of hair biology and drug screening on the hair growth. Hair follicles develop as a result of epithelial-mesenchymal interactions between epidermal keratinocytes and dermal papilla cells. We isolated and cultured some cell components of the human hair follicle, using explantation and enzymatic digestion method from human scalp skin, such as outer root sheath (ORS) cells, dermal papilla (DP) cells, dermal sheath (DS) cells, matrix cells and melanocytes. To induce hair morphogenesis in vitro the follicle cells were 3-D cultured simulating the normal skin structures. Moreover, to develop the organ culture model of hair follicle, we applied them in the dermal equivalent (DE) to expand hair growth period of the culturing hair follicles.