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일 도시 여자 고등학생에서 월경전기증후군 및 월경전불쾌장애와 우울, 수면의 질, 수면형태의 연관성
이지연,김석만,강석훈,정혜경,최진희,소형석,김태용,백기청,Lee, JiYeon,Kim, Seok Man,Kang, Suk-Hoon,Chung, HaeGyung,Choi, JinHee,So, HyungSeok,Kim, Tae Yong,Paik, Ki-Chung 대한불안의학회 2016 대한불안의학회지 Vol.12 No.2
Objective : Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is known to reduce the quality of sleep and is associated with various psychiatric disorders. The aim of this study was to investigate the relationship of PMS with depression, sleep qulity and sleep pattern in Korean female adolescents. Methods : Out of 867 high school female students, 400 female subjects were included in this study. All participants completed self-report questionnaires that included demographic variables, shortened premenstrual assessment form (SPAF), patient health questionnaire-9 (PHQ-9), Pittsburgh sleep quality index (PSQI), Epworth sleepiness scale (ESS), insomnia severity index (ISI) and Korean translation of composite scale (CS). A total of 394 individuals who completed the questionnaires were analyzed. Results : As score of SPAF, 143 subjects was defined PMDD group. They had more prevalence of eveningness, more depressive symptom, poorer sleep quality, and more excessive sleepiness than non-PMDD groups. Although the PMDD groups showed more menstrual dysmenorrhea, no difference was found in bleeding duration and cycle. PMS symptom had correlations with depression, poorer sleep quality and excessive sleepiness during the daytime. There was no difference in sleep duration between two groups, but PMS might have a relationship with eveningness of chronotype. Conclusions : Among Korean female high school students, the PMS might have an association with depression and poor sleep quality, and it might lead to daytime impairment due to excessive sleepiness. An appropriate evaluation of PMS could be helpful in determining the mental health condition of adolescents.
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특발성 렘수면 행동장애 환자와 정상인의 신경인지기능 특성 비교
김석만(Seok Man Kim),강석훈(Suk-Hoon Kang),정혜경(HaeGyung Chung),최진희(JinHee Choi),소형석(HyungSeok So),김태용(Tae Yong Kim),김태(Tea Kim),윤인영(In-Young Yoon) 대한생물치료정신의학회 2016 생물치료정신의학 Vol.22 No.3
Objectives:Rapid eye movement(REM) sleep behavior disorder(RBD) is a parasomnia characterized by loss of normal atonia during REM sleep and dream enacting behavior(DEB) including vocalizations, striking behaviors or violent movements. A proportion of RBD patients had showed mild cognitive decline, but it is controversial. This study has an aim to compare neurocognitive functions between idiopathic RBD(iRBD) and normal subjects in the Korean elderly. Methods:Twenty-six iRBD subjects and 25 normal controls were selected by polysomnography, brain magnetic resonance imaging and clinical interview with psychiatrist. All the subjects completed the Korean version of the consortium to establish a registry for Alzheimer’s disease neuropsychological battery(CERAD-KN) as an objective cognitive measure and subjective memory complaints questionnaire(SMCQ). Additionally Pittsburgh sleep quality index (PSQI) for sleep quality, the Epworth sleepiness scale(ESS) for daytime sleepiness and the Korean version of the geriatric depression scale(GDS) for depressive symptoms were done. Results:iRBD subjects showed poorer sleep quality with PSQI than normal controls, but there were no differences in other sleep parameters between groups. In the neurocognitive function test, iRBD subjects showed higher SMCQ score and lower score of Digit span backward test than normal controls. Conclusion:In the elderly, subjects with iRBD had subjective memory complaints and impaired attention function, but not other objective cognitive measures. As attention function as well as subjective memory complaints might an indicator for cognitive disorders, iRBD patients with mild cognitive decline needs to be adequately controlled.
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노인 특발성 렘수면행동장애 환자에서 보이는 자율신경증상과 그 관련 요인
고창민(Chang Min Go),강석훈(Suk Hoon Kang),최진희(Jin Hee Choi),정혜경(Hae Gyung Chung),김태용(Tae Yong Kim),소형석(Hyungseok So) 대한노인정신의학회 2013 노인정신의학 Vol.17 No.2
Objectives:Idiopathic REM sleep behavior disorder (RBD) is by far the strongest clinical predictor of neurodegenerative disease available. Several potential early diagnostic markers of neurodegenerative disease including autonomic symptoms have been proposed, but they have generally not been tested in presymptomatic neurodegenerative disease. So the authors investigated autonomic symptoms and their associated factors in idiopathic RBD patients. Methods:52 idiopathic RBD patients and 52 controls participated in the study. Autonomic symptoms were evaluated by applying the unified multiple system atrophy rating scale (UMSARS) and measuring orthostatic systolic blood pressure drop. Results:Idiopathic RBD patients showed significantly higher UMSARS subscale scores and sharper drop of orthostatic systolic blood pressure than controls. In multiple linear regression analysis, all autonomic symptoms and measured orthostatic systolic blood pressure drop were associated with RBD. In addition, orthostatic symptoms were associated with medication and age, urinary function was associated with benign prostatic hyperplasia, and measured orthostatic systolic blood pressure drop was associated with hypertension. Conclusion:In this study, idiopathic RBD patients showed more autonomic symptoms than controls. However, other autonomic symptoms-related factors also influenced some autonomic symptoms. Prospective studies should be performed to evaluate autonomic symptoms as a potential predictor of neurodegenerative diseases.
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