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이현숙(Hyeon Suk Lee),김대수(Dae Soo Kim),진영주(Young Joo Chin),김성진(Seong Jin Kim),송형근(Hyeong Keon Song),성노현(No Hyeon Seong),이상도(Sang Do Lee),김명수(Myeong Su Kim) 대한내과학회 1996 대한내과학회지 Vol.50 No.1
N/A Objectives: Interstitial penumonia is a major cause of death in scrub typhus but little is known about its pathology and pathogenesis. To study the clinical findings, pathology and pathogenesis of interstitial pneumonia in scrub typhus, we performed this study. Methods: We performed clinical evaluation, laboratory tests, radiological evaluation including high resolution CT and pulmonary function tests in 53 scrub typhus patients. Bronchoalveolar lavage(BAL) and transbronchial lung biopsy(TBLB) were done in patients with interstitial pneumonia and electron microscopic examination and immunofluorescence study including monoclonal antibody against Rickettsia tsutsugamushi were done. Results: 1) Interstitial pneumonia was found in 13(26%) patients. 2) Radiological findings: High-resolution CT showed diffuse ground glass opacity, thickening of bronchovascular bundie and prominent central core of secondary pulmonary lobule with minimal thickening of interlobular septum and there were no findings suggesting vasculitis 3) Cells in HAL fluid: total cell count, (46±9)×104/ml, alveolar macrophage, 68±17%, lymphocyte, 28±15% and neutrophil, 5±3% Pathologic finding(TBLH): 4) Light microscope: interstitial edema with mononuclear cell infiltration, mainly lymphocyte, without any evidence of vasculitis or perivasculitis 5) Immunofluorescence and eletron microscope ' IF study, using anti-Ig G,A,M, anti-Cg, anti-fibrinogen and anti-rickettsial Ab, revealed negative reaction. Electron photomicrograph revealed no rickettsial organism. Conclusion: In interstital pneumonia associated with scrub typhus we noted lymphocytosis in BAL fluid and interstitial inflammation in histopathology without any evidence of vasculitis. Thus vasculitis is not the only main pathology but other mechanism including immunopathogenesis may operate in the pathogenesis of intersititial pneumonia in scrub typhus
최기원 ( Choe Gi Won ),전원중 ( Jeon Won Jung ),채희복 ( Chae Hui Bog ),박선미 ( Park Seon Mi ),윤세진 ( Yun Se Jin ),신향미 ( Sin Hyang Mi ),성노현 ( Seong No Hyeon ),이상전 ( Lee Sang Jeon ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.3
Mature teratoma is the most common germ cell tumor of the ovary. The tumor is essentially a benign neoplasm and surgical resection of the tumor is the treatment of choice. Recurrence with colorectal involvement after surgical removal of the primary lesion is exceedingly rare and has not been reported in Korea. We present a 43-year-old patient with a rectal mass who had already undergone left oophorectomy due to mature cystic teratoma and right oophorectomy due to hemorrhagic corpus luteum. The rectal mass was composed of a mature teratoma tissue. We postulate that leakage of the tumor elements from the cyst wall led to peritoneal tumor implantation and invasion to the rectal wall. (Korean J Gastroenterol 2003;42:242-245)