http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 설상명 (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
내시경적 용종 절제술을 시행받은 145례의 위용종에 대한 임상 및 병리학적 연구
이연재,이상혁,설상명,정정명,윤혜경 인제대학교 1996 仁濟醫學 Vol.17 No.2
내시경 시술의 발달로 위에서 발생되는 여러 종류의 용종 중 크기가 악성일 경우는 외과적 절제술이 시행되고 있고 그 외 대부분의 병변은 내시경적 치료가 가능해졌다. 이런 점에서 저자는 위에서 발생되는 용종의 임상적, 병리학적 특징과 각종 내시경적 용종 절제술의 치료 효과와 안정성을 관찰하고자 하였으며, 내시경적 용종 절제술 후 추적 관찰하여 용종의 재발이나 위암의 발생을 확인하고자 한다. Gastric polyps are narrowly defined as macroscopically localized mucosal elevations composed of epithelial elements. They can be divided into two types : hyperplastic polyp and adenoma. Hyperplastic polyps usually occur in a chronically inflamed mucosa with a mild degree of atrophy and composed of normal-appearing epithelial cells, so hyperplastic polyps rarely become malignant. When dysplasia occurs to the polyps, malignant potential increases. Adenoma is composed of immature cells with varing degrees of dysplasia and its malignant potential is very high. So according to the size and pathologic findings, the therapeutic modalities are variable. And they should be removed for prevention of gastric cancer. We have performed endoscopic polypectomy such as snare polypectomy, strip biopsy or "O"ring ligation in 145 patients from July 1988 to June 1995 and evaluated the clinical characteristics, histopathology of the polyps. Twenty three patients who had had adenoma and had been undergone mucosectomy were followed up endoscopically for 6 to 24 months. The results were as follows : 1.One hundred and forty five patients were enrolled in this study. The ratio of male to female was 0.7:1(59 men, 86 females) and mean age was 50.4 (range: 31-79). The polyps were most frequent in the 6th decades of age. 2.The common clinical symptoms were epigastric discomfortness(41.3%), epigastric pain(29.7%), indigestion(17.9%) and abdominal discomfortness(6.9%). 3.The location of polyps were antrum(47.3%), body(45.0%) and fundus(7.7%). The number of patients with multiple polyps were 16(11.0%) and 139 patients had single polyp. The most frequent size of polyps was 0.5-1.0 cm and the next was 1-2 cm. 4.The gross findings of polyps by Yamada's classification were type II (35.5%), type III (29.6%), type I (21.3%) and type IV(13.6%). On histologic examination, hyperplastic polyps were 68.6% and adenomatous polyps were 23.7%. 5.The methods of polypectomy were mucosectomy in 23 cases(strip biopsy : 18, "O"ring ligation : 5) and snare polypectomy in 122 patients. If adenomatous polyps were reseated incompletely, we applied the laser therapy. When snare polypectomy could not be performed, strip biopsy was done. The effectiveness and rate of complications of mucosectomy was not different from that of snare polypectomy. 6.The most frequent complication of polypectomy was epigastric pain(23.4%) and the next was bleeding(14.5%). We could manage epigastric pain with medical therapy. The bleeding was controlled with Nd : Yac laser in five cases, with hypertonic saline-epinephrine injection therapy in five cases and with conventional medical therapy in 11 cases. 7.Among the patients with adenomatous polyps or dysplasia, we followed up 23 cases for 6 to 24 months (mean: 16 mon). There was no recurrence, but in one case gastric carcinoma was detected on other site. In the patients wish gastric polyp, polypectomy should be performed for precise diagnosis and treatment and the methods of polypectomy are taken according to their size and morphologies. Polypectomy is an effective preventive therapy for gastric cancer with low procedural complications.
-
-
정정명,임대건,이원식,최봉기,장윤식,이연재,이상혁,설상명,최하진 인제대학교 1996 仁濟醫學 Vol.17 No.2
1991년 1월부터 1993년 12월까지 인제의대 부산백병원에서 6개월 이상 HBsAg 및 HBeAg 양성이며 간조직 검사상 만성간염을 보인 환자들(활동성;26례, 지속성;3례)을 대상으로 알파 인터페론 치료시 혈청 전환 및 간기능 정상화율과 인터페론 투여에 따른 효과에 대해 분석하여 보았다. In order to evaluate the therapeutic efficacy and safety of recombinent alpha-interferon, we studied 29 patients proven to have chronic hepatitis B(CAH : 26 cases, CPH : 3 cases) through biopsy from January 1991 to December 1993. All patients were seropositive for HBeAg and HBsAg, and recieved alpha-interferon with tonal dosage up to 120 million units. The results were as follows ; 1) HBeAg sero-conversion rate was 51.7%(Total 15 cases including 3 cases in chronic per-sistant hepatitis group), and all these patients have showed normalized transaminase levels continously. 2) In response group, the serum transaminase level began to decrease at average 4.7th week after initiation of interferon. But in non-response group, the serum transaminase level began to decrease at 2nd to 4th week transiently after interferon, and then increased again. 3) Several adverse effects were noted during interferon treatment. General ache and myalgia were most common(65.5%), followed by fever and chillness(37.9%), headache(37.9%), leukopenia(17.2%) etc. But they were relatively tolerable. 4) Peripheral blood leukocyte counts showed slight reduction within 1 week after initiationof interferon treatment but rapidly recovered to normal level within 5 days after temporary withdrawal. And after completion of interferon treatment, no significant differences were remained compared with initial level. With these results, it suggests that α-interferon therapy may be effective and safe in chronic hepatitis B. However, further study will be required in non-responsive group thereafter.
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
