http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Primary Histiocytic Sarcoma of the Central Nervous System
소훈섭,김선아,윤덕현,강신광,황지혜,서충현,서철원 대한암학회 2015 Cancer Research and Treatment Vol.47 No.2
Histiocytic sarcoma is a type of lymphoma that rarely involves the central nervoussystem (CNS). Its rarity can easily lead to a misdiagnosis. We describe a patient withprimary CNS histocytic sarcoma involving the cerebral hemisphere and spinal cord,who had been initially misdiagnosed as demyelinating disease. Two biopsies werenecessary before a correct diagnosis was made. A histologic examination showedbizarre shaped histiocytes with larger nuclei and nuclear atypia. The cells werepositive for CD68, CD163, and S-100 protein. As a resection was not feasible due tomultifocality, he was treated with highdose methotrexate, but showed no response. As a result, he was switched to high dose cytarabine; but again, showed no response. The patient died 2 months from the start of chemotherapy and 8 months from theonset of symptoms. Since few patients with this condition have been described andhistopathology is difficult to diagnose, suspicion of the disease is essential.