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RISS 인기검색어
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정세윤,조숙희,김성훈,이응돈,서정일,강경옥,박상규,최진수,Jeong, S.Y.,Cho, S.H.,Kim, S.H.,Lee, E.D.,Seo, J.I.,Kang, K.O.,Park, S.G.,Choi, J.S. 한국전자통신연구원 2009 전자통신동향분석 Vol.24 No.1
세계 주요 나라에서 HDTV 방송이 서비스되고 있으며, 현재는 아날로그와 디지털 방송이 동시 송출되고 있으나, 2010년대 초기에 디지털 전환을 완료할 예정이다. 방송서비스는 기술개발, 표준 제정 및 법제 정비 등 많은 개발 및 준비기간을 필요로 하므로, 세계 주요 국가들은 HDTV 이후의 방송 서비스를 위한 준비 작업들을 진행하고 있다. HDTV 이후의 차세대 방송을 UHDTV라고 하며, 가정에서 70 mm 영화보다 뛰어난 화질(비디오 해상도 $7680{\times}4320$, HD 화면 16배 크기에 해당)과 다채널(${\sim}22.2ch$) 음질로 극장급의 초고품질 서비스를 제공하여 소비자의 품질 욕구를 만족시킬 수 있는 TV를 목표로 한다. 본 고에서는 UHDTV 서비스에 필요한 관련 기술 동향과 표준화 동향 및 기술 개발시 선행적으로 필요로 하는 특허 동향에 대해서 설명한다.
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한국인에서 심바스타틴의 효과와 부작용 분석을 위한 다기관 공동 임상 연구
박영배 ( Young-Bae Park ),서정돈 ( Jung-Don Seo ),배종화 ( Jong-Hwa Bae ),노영무 ( Young-Moo Rho ),이원로 ( Won-Ro Lee ),손민수 ( Min Soo Son ),채성철 ( Shung-Chull Chae ),김권삼 ( Kwon-Sam Kim ),김권배 ( Kwon Bae Kim ),안정천 ( J 대한내과학회 1999 대한내과학회지 Vol.57 No.5
The aim of this study was to investigate the efficacy of simvastatin to improved lipid profiles in hypercholesterolemic Korean patients. Methods : From 25 hospitals in Korea, 478 hypercholesterolemic patients were enrolled from November 1996 to April 1998. The inclusion criteria was hypercholesterolemia over 240 mg/dl after diet therapy for 1 month or hypercholesterolemia over 220 mg/dl in patients with definite evidence of ischemic heart disease. Simvastatin 10mg was started and doubled up to 40mg if total cholesterol level remained higher than 200 mg/dl at monthly check. Of 478 subjects, 344 patients in whom study protocol was not violated were analyzed. Results : Male to female ratio was 27:73 and 47% of the subjects were in 6th decade. Hypertension, coronary artery disease, and diabetes mellitus were present in 30, 10, and 4% of the subjects. Baseline lipid profile (mean of total cholesterol-LDL-HDL-triglyceride mg/dl) was 274-185-52-188. The dose of simvastatin for 3 months was 10/10/10mg in 61% of subjects, 10/20/20mg in 21%, 10/10/20mg in 7%, and 10/20/40mg in 12%. The change of total cholesterol level(before-4wk-8wk-12wk-withdrawal 4wk) was 274-209- 205-198-250, and the maximal reduction rate was 27%. The change of LDL-cholesterol was 185-123-116-110-159, with maximal reduction rate 39%. The change of HDL-cholesterol was 52-54-56-55-54, with maximal increase rate 9%. The change of tryglyceride was 188-161- 164-162-189, with maximal reduction rate 15%. The value before/after treatment of ApoA1, ApoB, and Lp(a) was 129/129, 138/83, and 9.3/10.7, respectively. The level of LDL-cholesterol at the end of treatment was below 100mg/dl in 36% of subjects, 100-130 in 45%, 130-160 in 16%, and over 160mg/dl in 4%. The reduction rate of LDL-cholesterol was different between subjects whose LDL decreased below 100 and those whose LDL did not decrease below 130mg/dl, which suggests the existence of the individual difference of responsiveness to simvastatin. There were only 3 subjects (0.9%) who showed increase of liver enzyme over 3 times as the upper normal limit. Conclusion: Simvastatin is effective in improving lipid profiles in hypercholesterolemic Korean patients without serious side effects. (Korean. J. Med 57:906-915, 1999)
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휴식 / 부하 심근 Rubidium - 82 양전자단층촬영과 부하 / 휴식 심근 Tc - 99m - MIBI 단일광자단층촬영의 비교
이동수(D . S . Lee),정준기(J . K . Chung),이명철(M . C . Lee),고창순(C . S . Koh),이경한(K . H . Lee),강건욱(K . W . Kang),정재민(J . M . Jeong),곽철은(C . Kwark),서정돈(J . D . Seo) 대한핵의학회 1995 핵의학 분자영상 Vol.29 No.1
N/A We compared stress/rest myocardial Tc-99m-MIBI tomographic image findings with rest/stress rubidium-82 tomographic images. In 23 patients with coronary artery disease (12 of them received bypass grafts before) and 6 normal subjects, rest rubidium PET study was performed, rubidium-82 and Tc-99m-MrBI were injected simultaneously to each patient after dipyridamole stress for rubidium PET and MIBI SPECT; and rest MIBI SPECT was performed 4 hours thereafter. We scored segmental decrease of rubidium, or MIBI uptakes into 5 grades for 29 segments from 3 short-axis, vertical and horizontal slices. Scores were summed for each major arterial territory. When more score than two grade-2's or one grade-3 was considered as the cue for significant stenosis for major arterial territories, 67% of 46 stenosed arteries were found with MIBI studies and 78% of them by rubidium studies. Fourteen among 28 grafted arterial territories of 12 post-CABG patients were found normal with both rubidium and MIBI. Segmental scores were concordant between rubidium and MIBI in 72% of 709-stress segments and in 80% of 825 rest segments. Stress rubidium segmental scores were less than stress MIBI scores in 9%, so were rest rubidium scores. Stress rubidium scores were more than stress MIBI scores in 20% of segments, and rest rubidium segmental scores were more than rest MIBI scores in 11%. Rank correlations (Spearman's rho's more than 0.7(stress) and 0.5(rest), slopes (MIBI/rubidium) around 0.7(stress) and 0.9(rest) suggested deeper and wider defects in stress with rubidium. Slope over 1 (MIBI/rubidium) with LAD segemental scores at rest and 7 territories which had much larger score with MIBI revealed exaggeration of rest defects with rest MIBI in same-day stress/rest study. Difference scores (stress-rest for each territory) suggesting ischemia were larger with rubidium (slope of MIBI/rubidium around 0.45). As has been implied by animal or separate-day- human studies, these segmental analyses with simultaneous examination in patients told that rubi
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