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서운규,정지천,朴宣東 東國大學校韓醫學硏究所 1994 東國韓醫學硏究所論文集 Vol.3 No.-
In order to investigate the effect of Mangumtang(MT) and Gamimangumtang(GMT) experi-mental studies were performed in Ex.1(treated with cholesterol and administration of sample at a time) and Ex2.(administration of sample after the treatment of cholesterol). The results were summerized as follows : 1.The content of Total cholesterol in the serum was not significantly decreased in MT group, whereas in GMT group sinificantly decreased compared with control group in Ex.1 and all significnatly decreased in MT group and GMT group in Ex.2. 2.The content of Triglyseride in the serum was all significantly decreased in MT group and GMT group in all case. 3.The content of Phospholipid in the serum was not significantly decreased in MT group, whereas in GMT group was significantly decreased compared with control gruop in Ex.1 or Ex.2. 4.The content of Free Fatty Acid in the serum was significantly decreased in MT group and GMT group in all case. 5.The content of HDL-Cholesterol in the serum was tended to decreased compared with control group but did not show a significance in Ex.2 or Ex.2. 6.The content of LDL-Cholesterol in the serum was not significantly decreased in MT group and GMT group in Ex.1, whereas in Ex.2 not significantly decreased in MT group but significantly decreased in GMT group. According to the above results, it is assumed that Mangumtang and Gamimangumtang have a vaild effect on Hyperlipidemia. especially Gamimangu-mtang have a more valild effect on prevention and cure of Hyperlipidemia.
Effects of Scolopendrae corpus on Immune Response in Mice of Different Ages
김길섭,서운규,정지천,김철호,이동목,송해범,이항우,남경수 한국생명과학회 1998 한국생명과학회 학술발표회 Vol.20 No.-
To clarify the activating effects of Scolopendrae corpus on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Scolopendrae corpus increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Scolopendrae corpus also increased natural killer cell activity concerning to cancer immunology. These results suggest that Scolopendrae corpus markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.