태아 신장기형 중 Infantile polycystic kidney 1례

고일영(Il Young Ko),정창호(Chang Ho Jung),송진범(Jin Berm Song),서경용(Kyung Young Seo),심재식(Jae Sik Shim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.9

The infantile polycystic kidney disease is rare fetal urinary tract anomaly. It is inherited with an autosomal recessive pattern and recurrence rate is 25%. The gene locus is on chromosome 6p. The pathogenesis of infantile polycystic kidney is the primary defect of the collecting ducts. The ultrasonographic finding of infantile polycystic kidney is oligohydramnios, bilaterally symmetrical enlarged kidneys with maintenance of their reinform shape. The differential diagnosis with adult polycystic kidney disease is important. The massive enlargement of the kidneys is rarely seen in adult polycystic kidney disease and the examination of the parents and other members of the family is helpful to confirm the adult polycystic kidney disease. If there is severe renal involvements, stillbirth or neonatal death secondary to pulmonary hypoplasia would be developed. If it were diagnosed before viability, termination of pregnancy is recommended. In a fetus at risk, diagnosed after viability, pregnancy termination is also recommended since this condition is uniformly fatal. We present a case of infantile polycystic kidney.

자궁내막 전체의 표재성 전파 동반 및 양측 난관 장막을 관통하여 양측 난소를 침범한 자궁경부편평세포암종

주정경 ( Jung Kyung Joo ),강지현 ( Ji Hyun Kang ),주인숙 ( In Sook Joo ),박양순 ( Yang Soon Park ),이정원 ( Jung Won Lee ),서경용 ( Kyoung Young Seo ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.7

Squamous cell carcinoma is one of the commonest malignancies of the uterine cervix and it is a significantly rare phenomenon of metastases to the bilateral ovaries by endometrial and transtubal spreading in the absence of lymph node involvement. The data is limited because it is still difficult to determine the optimal treatment and the prognostic significance is uncertain. We report a 66-year-old woman with squamous cell carcinoma, International Federation of Gynecology and Obstetrics stage Ia2, without previous radiation therapy, associated with superficial spreading squamous cell cervical carcinoma involving the entire endometrial cavity, bilateral tubes and bilateral ovaries.

한국여성에서 폐경 후 Drospirenone 2 mg과 17-β-Estradiol 1 mg 투여의 혈압 및 체중에 대한 효과

신미영 ( Mi Young Shin ),위찬우 ( Chan Woo Wee ),주정경 ( Jung Kyung Joo ),강지현 ( Ji Hyun Kang ),주인숙 ( In Sook Ju ),서경용 ( Kyoung Young Seo ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.10

목적: 폐경 후 한국 여성에서 Drospirenone 2 mg (DRSP)과 17-β-Estradiol 1 mg (E2) 투여의 혈압 및 체중에 대한 효과를 평가하였다. 연구 방법: DRSP/E2 투여 전과 3개월 후에 혈압과 체중을 측정하였다. DRSP/E2 투여 전 혈압이 정상혈압 (group 1, 대조군)과 높은정상혈압 (group 2)인 군의 혈압과 체중의 변화를 비교하였으며, 항고혈압제를 복용 중인 고혈압 환자로 DRSP/E2를 추가 투여한 군 (group 3)과 투여하지 않은 군 (group 4, 대조군)의 혈압과 체중도 비교하였다. 결과: Group 1의 평균 수축기 및 이완기 혈압은 변화 없었으나 (P=0.152/P=0.088), group 2의 평균 수축기 및 이완기 혈압은 유의하게 감소하였다 (P<0.001/P=0.002). Group 3의 평균 수축기 및 이완기 혈압은 유의하게 감소하였으며 (P<0.001/P<0.001), group 4의 평균 수축기 및 이완기 혈압도 유의하게 감소하였다 (P=0.002/P<0.001). 그러나 group 3의 혈압 감소가 group 4보다 유의하게 컸다 (P=0.041/P=0.024). DRSP/E2 투여 전, 후 체중은 모든 군 유의한 변화는 없었다. 결론: 폐경 후 한국 여성에서 DRSP/E2의 투여는 높은정상혈압 이상의 혈압을 낮추며, 고혈압 환자에서 항고혈압제와 병용시 더 크게 낮추는 경향을 보였다. 그러나 투여 전, 후 체중의 유의한 차이는 없었다. Objective: To evaluate effects of Drospirenone 2 mg (DRSP) with 17-β-Estradiol 1 mg (E2) on blood pressure (BP) and body weight in postmenopausal Korean women. Methods: BP and body weight were measured at baseline and 3 months of the treatment. We compared the change in BP and body weight between normotensive (group 1, control) and high-normotensive (group 2) group during treatment. And we compared the change in BP and body weight between hypertensive group receiving anti-hypertensive with (group 3) and without (group 4, control) DRSP/E2 during treatment. Results: The mean systolic BP/diastolic BP of group 1 was not significantly decreased from baseline (116.9/75.0 mmHg) after treatment with DRSP/E2 for 3 months (116.1/73.2 mmHg) (P<0.152/P=0.088), however that of group 2 was significantly decreased from baseline (128.8/81.8 mmHg) after treatment with DRSP/E2 for 3 months (126.2/79.3 mmHg) (P<0.001/P=0.002). The mean systolic BP/diastolic BP of group 3 was significantly decreased from baseline (133.5/82.5 mmHg) after treatment with DRSP/E2 for 3 months (129.3/77.9 mmHg) (P<0.001/P<0.001), and that of group 4 was also significantly decreased from baseline (133.2/80.7 mmHg) after treatment with DRSP/E2 for 3 months (131.0/78.3 mmHg) (P=0.002/P<0.001). However change in the mean systolic BP/diastolic BP of group 3 was greater than that of group 4 (P=0.041/P=0.024). There was no weight change in all four groups. Conclusion: The use of DRSP/E2 showed a tendency to decrease the BP of high-normotensive or above in postmenopausal Korean women, and hypertensive patients receiving anti-hypertensive showed greater decline in BP. However there was no statistical significance in body weight change.

자궁근층 침윤을 동반한 일차성 자궁장막임신

강민정 ( Min Jung Kang ),주정경 ( Jung Kyung Joo ),강지현 ( Ji Hyun Kang ),주인숙 ( In Sook Joo ),박양순 ( Yang Soon Park ),서경용 ( Kyoung Young Seo ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.3

Ectopic pregnancy is reported to be 1.5%-2% of all pregnancies. Ectopic pregnancy varies with the site of implantation; abdominal pregnancy has been reported to occur in approximately 1% of patients with ectopic pregnancy. Especially, uterine serosal pregnancy is an extremely rare form of abdominal pregnancy. Although variable diagnostic imaging methods have been developed, accurate diagnosis of the abdominal pregnancy using noninvasive imaging study is still diffi cult. Delayed diagnosis leads to high maternal morbidity and mortality in relation to massive bleeding. Therefore, diagnostic laparoscopy or laparotomy is generally considered to patients with uncertain diagnosis of the abdominal pregnancy. We experienced a case of primary uterine serosal pregnancy that had a rupture of gestational sac with myometrial invasion. We finally confirmed a definite site of the ectopic pregnancy through laparoscopic exploration. That precise location could be not found by pelvic ultrasonography and magnetic resonance imaging. The patient underwent a subtotal hysterectomy.

임신 제 3 분기에 자연 파열된 비장동맥류파열 1 예

이혜은(Hea Eun Lee),정병훈(Byoung Hun Joung),노주영(Ju Young No),주인숙(In Sook Joo),심재식(Jae Sik Shim),서경용(Kyung Young Seo) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.6

The spontaneous rupture of splenic artery aneurysm during pregnancy is a rare but catastrophic event. Two thirds of all ruptures happen during the third trimester. Clinical presentation is often non-specific, with good hemodynamic compensation, followed by a rapid deterioration. Active management and operation are the most important procedures for diagnosis and therapy of the bleeding. Abdominal delivery will help to establish diagnosis and should be performed immediately. We report a case of a patient at 38 weeks of gestation suffering epigastric pain and fetal distress. At emergency cesarean delivery, an aneurysmal rupture of the splenic artery was found to be the reason for the hemoperitoneum. Spleen, aneurysm and the tail of the pancreas were removed. In spite of fatal hemorrhage, the patient survived but her fetus was dead. With a review of the literature on this topic, diagnostic aspects and treatment options are discussed.

병합임신의 1례

송진범 ( Jin Berm Song ),이혜은 ( Hye Eun Lee ),정병훈 ( Byung Hoon Jung ),주인숙 ( In Sook Joo ),서경용 ( Kyung Young Seo ),심재식 ( Jae Sik Sim ) 대한주산의학회 2001 Perinatology Vol.12 No.2

자궁근종환자에서의 골 밀도와 혈중 지질 동태에 관한 연구

신경자,서용수,최두석,윤병구,서경용,이재호 대한폐경학회 1996 대한폐경학회지 Vol.2 No.2

To testify the hypothesis that BMD and serum lipid profiles might be different in women with leiomyoma, estrogen-dependent tumor, retrospective study was perfarmed in healthy women who visited Health Promotion Center in Samsung Medical center. One hundred sixty-one women with leiomyoma diagnosed by pelvic ultrasound examination were compared with 315 women with normal uterus. All women were divided into 3 groups accarding to serum FSH levels(mIU/ml)-group 1: FSH$lt;20, group 2: 20≤FSH$lt;35, group 3: FSH≥35. BMD tends to be higher in patients with leiomyoma than control. In group 1, women with leiomyoma showed higher femur BMD at trochanter and Ward's triangle(p$lt;0.05). Serum lipid profiles also seemed to be better in leiamyoma patients higher total and HDL cholesterol levels in group 1, elevated HDL cholesterol concentrations in group 2, and lower LDL cholesterol levels in group 3(p$lt;0.05). These data suggest that estrogen-sensitive markers such as BMD and serum lipid profiles tend to be improved in women with leiomyoma compared with control. A hyper-estxogenic state co-existing with leiomyoma might contribute to these differences. $quot;