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박창남,양원준,배연지,이용덕,강완철,안미정,신태균,Park, Changnam,Yang, Wonjun,Bae, Yeonji,Lee, Yongduk,Kang, Wanchoul,Ahn, Meejung,Shin, Taekyun 대한수의학회 2013 大韓獸醫學會誌 Vol.53 No.1
The vomeronasal organ (VNO) plays an important role in reproduction and social activities in ruminants including goats. A morphological study on the structure of VNO and its epithelial cells was carried out in Korean black goats. Grossly, the VNO of Korean goats opens into mouth through incisive ducts. Microscopically, the epithelium of VNO consisted of medial sensory epithelium and lateral non-sensory epithelium. Several blood vessels and nerve bundles were observed in the lamina propria encased by vomeronasal cartilage. Immunohistochemical staining showed that protein gene product (PGP) 9.5 was immunostained in the receptor cells of the sensory epithelium and in some cells of the non-sensory epithelium. Galectin-3 was mainly observed in the supporting cells of sensory and non-sensory epithelium. Lectins including wheat germ agglutinin, Ulex europaeus agglutinin, Bandeiraea simplicifolia lectin Isolectin B4, Dolichos biflorus agglutinin and soybean agglutinin used in this study were bound in VNO sensory, non-sensory epithelia as well as in the lamina propria with varying intensity. Collectively, this is a first descriptive morphological study of VNO of Korean black goat with special reference to lectin histochemistry.
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Trimethyltin에 의한 랫드 해마의 신경세포 사멸과 iNOS의 연관성
장석원,최성영,박창남,안미정,신태균,김승준,Jang, Sukwon,Choi, Sungyoung,Park, Changnam,Ahn, Meejung,Shin, Taekyun,Kim, Seungjoon 대한수의학회 2011 大韓獸醫學會誌 Vol.51 No.3
Trimethyltin chloride (TMT) has been used as a neurotoxin for inducing brain dysfunction and neuronal death. Neuronal death in the hippocampus by TMT may generate excessive nitric oxide, but there are few studies about nitric oxide synthase enzyme involved in the synthesis of nitric oxide. The purpose of present study is to analyze the TMT toxicity in each region of rat hippocampus. To evaluate the involvement of nitric oxide, we analyzed the effects of aminoguanidine known as a selective inhibitor for inducible nitric oxide synthase on behavioral changes and the hippocampus of rat by TMT toxicity. 6-week-old male Sprague-Dawley rats were administered with a single dose of TMT (8 mg/kg b.w., i.p.) and the control group was similarly administered with distilled water. TMT + aminoguanidine-treated groups were administered with aminoguanidine (10 mg/kg or 100 mg/kg b.w., i.p.) for 3 days prior to TMT injection. The rats were sacrificed 2 days after TMT administration. In the TMT-treated group, a number of cell losses were seen in CA1, CA3 and the dentate gyrus. In the TMT + aminoguanidine-treated group, neuronal death was seen in CA1 and CA3, but reduced in the dentate gyrus compared to the TMT-treated group. Western blot analysis showed that cleaved caspase-3 expression was increased in the TMT-treated group compared to the control group. However, the expression significantly declined in the TMT + aminoguanidine-treated group. The present findings suggest that inducible nitric oxide synthase is involved in neuronal death induced by TMT.
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최적합 구름 베어링용 Urea계 그리이스의 특성평가 연구
김상근(Sangkeun Kim),박창남(Changnam Park),한종대(Jongdae Han) 한국트라이볼로지학회 2005 한국트라이볼로지학회지 (Tribol. Lubr.) Vol.21 No.1
Rolling bearings are assorted one of the most important machine elements. The various functions of bearings are greatly influenced by grease, and higher performance of rolling bearing greases is required to improve rolling bearing lubrication. The two conditions for optimum grease synthesis were selected by SSRED (Six Sigma Robust Engineering Design) program by using dropping points and OIT values respectively. And the optimized two urea/ether oil greases were synthesized to compare the performance. The typical physical properties of grease were investigated. And life test of these greases was conducted by rolling bearing grease life tester. The characteristics of the greases before and after life test were investigated using FTIR, microscope, SEM, TG/DSC, OIT and TAN meter. The optimized two greases showed longer life time than typical urea/ether oil grease. The optimized grease by means of OIT value showed higher performance such as long life time, low TAN value and high oil bleeding amount in comparison with the optimized grease using dropping point.
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최적합 구름 베어링용 Urea계 그리이스의 특성평가 연구
김상근(Sangkeun Kim),박창남(Changnam Park),한종대(Jongdae Han) 한국트라이볼로지학회 2004 한국트라이볼로지학회 학술대회 Vol.39 No.-
Rolling bearings are assorted one of the most important machine elements. The various functions of bearings are greatly influenced by grease. and higher performance of rolling bearing greases is required to improve rolling bearing lubrication. The two conditions for optimum grease synthesis were selected by SSRED (Six Sigma Robust Engineering Design) program by using dropping points and OIT values respectively. And the optimized two urea/ether oil greases were synthesized to compare the performance. The typical physical properties of grease were investigated. And life test of these greases was conducted by rolling bearing grease life tester. The characteristics of the greases before and after life test were investigated using FTIR. microscope. SEM. TG/DSC, OIT and TAN meter. The optimized two greases showed longer life time than typical urea/ether oil grease. The optimized grease by means of OIT value showed higher performance such as long life time. low TAN value and high oil bleeding amount in comparison with the optimized grease using dropping point.
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