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안구를 포함한 다발성 장기손상이 동반된 특발성 호산구증가 증후군 1예
박은재(Yeun Jae Park),조용범(Young Bum Joo),이지영(Ji Young Lee),신승용(Seung Yong Shin),이문희(Moon Hee Lee),이홍복(Hong Bock Lee),김철수(Chul Soo Kim) 대한내과학회 2000 대한내과학회지 Vol.58 No.6
N/A The idiopathic hypereosinophilic syndrome is a disorder marked by the sustained overproduction of eosinophils. The disease is characterized clinically by damage to multiple organs due to eosinophilic infiltration and mediator release rather than by the level of the absolute blood eosinophil count. We report a case of hypereosinophilic syndrome presenting multiple organ damages with eyeball involvement.(Korean J Med 58:692-697, 2000)
간경변증 환자에서 고암모니아혈증과 Helicobacter pylori의 연관성
김영수,최원,신현주,신용운,권계숙,이돈행,김범수,조현근,이재수,홍의수,박은재 대한소화기학회 1999 대한소화기학회지 Vol.34 No.3
Background/Aims: We examined the correlation between hyperammonemia and gastric Helicobacter pylori (H. pylori) infection in patients with liver cirrhosis. Methods: We studied 31 patients with liver cirrhosis and 34 normal controls. However, the cirrhotic group did not include patients who had a bleeding tendency or hepatic encephalopathy. We performed gastroscopy, obtained gastric juice (3-4 mL) and antral biopsy specimens, and examined the ammonia levels of blood and gastric juice in each group. Results: In the cirrhotic group, there was no difference in blood ammonia levels between the H. pylori- positive (HP+) and negative (HP-) groups. However, the ammonia levels of gastric juice in the HP+ group showed a tendency to be higher than those in the HP- group (p=0.0773). Child-Pugh scores in the HP+ group were significantly lower than those in the HPQ group (p= 0.0309). By multiple regression analysis, factors affecting the ammonia levels of blood were determined. They were age (coefficient 1.2462, p=0.0256) in the control group (r2=0.2821), and ammonia levels of gastric juice (coefficient 0.007417, p=0.0322) in the cirrhotic group (r2=0.3127). On the other hand, Child- Pugh scores (coefficient 12.508122, p=0.0883) indicated a slight correlation with the blood ammonia levels in the cirrhotic group. Conclusions: It seems that gastric H. pylori infection is associated with hyperammonia in patients with liver cirrhosis.