박양자 , 이순복 , 변동길

박양자,이순복,변동길 대한피부과학회 1974 大韓皮膚科學會誌 Vol.12 No.2

Although the psoralen therapy has been used extensively on vitligo since the : introduction by El-Mofty on 1948, the result has not been satisfactory. Recent investigations showed that the autoimmune mechanism might be the causative factor to the development of vitiligo, and the use of steroid might be expected to be beneficial in the treatment of this disorder. Authors tried the combined treatment of prednisolone and psoralen on vitiligo and the results obtained are as follows; 1. Repigmentations began to develop from injected area of prednisolone as well as frorn hair follicles and peripheral area of the lesions. 2. More satisiactory responses were obtained on the widespread and symmetrical lesions of shorter duration than on the lesions of localized and long duration.

들깨박의 첨가가 흰쥐의 지질대사에 미치는 영향

이승교(Seung Gyo Rhie),박양자(Yaung Ja Park) 한국식품영양과학회 1991 한국식품영양과학회지 Vol.20 No.1

라드ㆍ콜레스테롤을 사용한 식이에 들깨박을 식이섬유소로 사용하여 흰쥐의 지질대사변화를 알아보고자 혈청, 변 및 간조직의 총지질 및 콜레스테롤, 중성지방, 인지질을 분석하였다.<br/> 실험식이 간의 증체량 식이섭취량 사료효율은 차이가 없었으며 혈청콜레스테롤과 중성지질은 들깨박 첨가식이군에서 현저히 낮았다. 변중의 총지질과 콜레스테롤 및 중성지질은 들깨박첨가식이군이 훨씬 높았으며 간의 지질성분은 유의적인 차이가 없었으나 인지질은 들깨박 첨가군에서 유의성있게 높았다. 이로서 들깨박은 변중의 지질배설증가와 간의 인지질함량을 증가시킴으로서 혈청콜레스테롤과 중성지질의 농도를 저하시키는 효과를 가져왔다고 본다. This study was designed to observe the effect of defatted perilla as a dietary fiber on lipid components of serum, feces and liver in rats. Serum cholesterol and triglyceride were signficantly decreased in defatted perilla added groups. Total lipid, cholesterol and triglyceride of feces were significantly increased in defatted perilla added groups. Liver phospholipid content was higher in the defatted perilla added groups. The other lipid components of the liver were not affected by the defatted perilla administration. These results suggest the possibility that defatted perilla have a reducing effect of serum cholesterol and triglyceride through the increment of fecal excretion of lipid component and phospholipid in liver.

매독 환자의 혈청 검사 비교

박양자,김진택 대한적십자사 1976 적십자병원지 Vol.3 No.2

흰쥐와 수탉에 있어서 가열처리가 쌀과 보리, 밀 대두의 필수아미노산 이용율에 미치는 영향

박양자,이영선,한인규,이재준,김승욱,하종규 한국콩연구회 1988 韓國콩硏究會誌 Vol.5 No.1

국산 쌀과 보리, 밀 대두의 볶기와 autoclaving에 따른 Wister계통의 흰쥐와 single combed white Leghorn 수탉에서의 필수아미노산 이용성에 미치는 영향을 알아 보았는데, 곡류와 대두에 있어서 볶기는 전반적으로 아미노산 함량을 감소시켰고 라이신과 타이로신의 감소가 컸다. 필수아미노산 이용성을 보면, 사용한 시료의 종류에 따라, 가열처리 방법에 따라, 동물에 따라 다른 것으로 나타났다. 사용한 시료중에 쌀과 대두의 아미노산 이용성은 흰쥐와 수탉 모두에서 높았고, 밀의 아미노산 이용율이 두 동물 모두에서 낮았다(P$lt;0.05). 필수아미노산간의 이용성 차이를 보면, 이소루신과 루신, 발린, 페닐알라닌, 히스티딘이 높았고(P$lt;0.05), 라이신과 타이로신의 이용성이 낮았다(P$lt;0.05). 또한 autoclaving은 볶은 경우 보다 전반적으로 필수아미노산의 함량을 감소시켰다. 발린 및 메치오닌, 이소루신, 타이로신은 autoclaving 경우 볶은 경우보다 더 높았다.

Corticosteroid 제 남용으로 온 Striae Distensae 1 예

박양자,현종명,이란희 대한피부과학회 1976 大韓皮膚科學會誌 Vol.14 No.3

In 1932, Harris, et al., reported that vitamin A had an anti-keratinizing effect on acne vulgaris, and in 1948, Straumfjord, somewhat over-enthusiastically reported that oral use of vitamin A also had a beneficial effect on acne. In spite of studies by Lynch and Cook (1947), and Andrew and Stokoe (1963), which questioned its effectiveness, the original enthusiasm for this regimen has not been completely dampened. Kligman (1969) reported that vitamin A acid (VAA), a metabolic end-product of vitamin A metabolism, produced a peeling effect and when applied topically, was effective in tbe treatment of acne. The mechanism of action of VAA is incompletely understood, however, it is observed to cause, arnong other things, an increase in the speed of proliferation of the cells of the epidermis; dissolution of the intracellular lysosomes; increase in the rate of keratin formation and the conversion of hard keratin to soft keratin; and an increase in the secretion of the sebaceous glands. The effect of VAA in acne treatment is due to the increase in the secretion of the sebaceous glands which prevents the formation of comedones. It is believed that the increased speed of cell division, increased keratinization and softening of the keratin cause a weakening of the intercellular adhesion. These processes cause an acceleration of the flow of cells out of the sebaceoua glands which prevents the formation of comedones and forces existing comedones to the surface of the skin. For this study, thirt:y eight patients with acne vulgaris were selected from among the outpatients of Severance Hospital. They were divided into two groups. The first group was treated with application of vitamin A acid alone. The second group was treated concurrently with topical vitamin A acid and oral tetracycline.

Gas - liquid chromatography 에 의한 한국 주요식품의 아미노산 함량측정

박양자,Sirny, Robert J 한국농화학회 1969 Applied Biological Chemistry (Appl Biol Chem) Vol.12 No.1

The purpose of this study was to determine protein amino acid contents of some Korean foods by gas-liquid chromatography, and to evaluate this technique as a procedure for the quantitative determination of amino acids in foods. The crude protein content of foods was also estimated from the nitrogen content. 1. Nitrogen content of each food sample was determined previously to adjust the amount of sample for GLC analysis 2. In the analysis of 17 known amino acids, a linear relationship was found between the weight of 13 amino acids of 17 amino acids, the internal standard as well as the injection volume of a mixture and the detector responses for the derivatives of the amino acids. No response for arginine, cystein, histidine, and tyrosine was observed. 3. The relative molar response (RMR) values for the 13 amino acids of standard solution relative to glutamic acid as $quot;1.00$quot; were obtained under normal operating conditions with a hydrogen flame ionization detector. 4. The recovery of amino acids from their mixtures with natural food materials was carried out. The recoveries were essentially quantitative except threonine and serine. An overall mean recovery of 11 amino acids was 101.4±8.4 per cent before hydrolysis and 98.1±8.7 per cent after hydrolysis of samples. 5. The comparative analysis of the acid hydrolysates of two food samples by gas-liquid and ion-exchange chromatographic analysis were carried out. In white-bait pemmican, only threonine and asparagine amounts by GLC analysis had similar values to those obtained by ion-exchange chromatography. The other seven amino acids gave higher values as measured by GLC than by ion-exchange. With the food sample, soybean, alanine, valine, asparagine, and glutamic acid were in good agreement in two analysis, while leucine, proline, threonine, phenylalanine, and lysine were found in slightly higher concentrations in the GLC analysis. 6. Grant variations of amino acid content were found among samples analyzed. The amino acid contents of each sample were compared with the values found in the literature.

건선치료에 있어서 Methotrexate의 효과 및 부작용

박양자,김진택 대한적십자사 1979 적십자병원지 Vol.6 No.2

수종(數種) 만성피부질환에 대한 Strontium 90의 임상효과

박양자 대한피부과학회 1972 大韓皮膚科學會誌 Vol.10 No.3

Some of chronic benign recurrent dermatoses are markedly recalcitrant to the ordinary dermatological treatments. The author studied the therapeutic effect of beta ray on those of 30 patients including 6 cases of psoriasis, 3 of lichen simplex chronicus, 9 of nummular eczema, 8 of pustulosis palmaris et plantaris, and 4 of chronic eczema of the finger. All of the above were promptly recurred with ordinary treatments. Strontium 90 applicator was used as the source of beta ray and the total irradiation doses to each sites were ranged from 600 to 1500 rads in divided doses(usually weekly) over 2 to 3 weeks. The results were as follows, 1. In psoriasis patients with papular type were cleared by strontium 90, however, with chronic localized plaque type were poorly responded. The relapses of the cleared papular type were noticed between 13 to 24 days intervals, and it appeared that the larger doses did not influence significantly the clinical results. 2. Almost all of the chronic eczematous dermatoses including lichen simplex chronicus, nummular eczema, pustulosis Palmaris et plantaris, and chronic eczema of the finger, which were irradiated by beta rays following clearance with preliminary corticosteroid therapy, were recurred between 2 to 4 weeks intervals. However, larger doses resulted in prolonged recurrence intervals in a few patients. 3. No noticeable eariy hazards of irradiation were detected except for the mild hyperpigmentation on the irradiated skin.

퇴계학에 있어서의 자연관과 인간관 ; 퇴계의 자연관 - 특히 출처진퇴관을 (出處進退觀) 중심으로 -

박양자 퇴계학연구원 1992 退溪學報 Vol.75 No.1

유교(儒敎)와 현대여성(現代女性)

박양자 퇴계학부산연구원 1996 退溪學論叢 Vol.2 No.-