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Myungsu Park(박명수),Yunhee Ku(구윤희),Sehyun Shin(신세현),Jangsu Suh(서장수) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4
The light-transmission technique has been applied to a slit rheometer for measuring red blood cell aggregation as well as blood viscosity over a range of shear rates. For measurement of blood viscosity and aggregation, instantaneous pressure and transmit-light intensity are measured with time. Using a precision pressure measurement, one can determine the shear stress and shear rate. In addition, a transmitted light through a blood sample indicates degree of RBC aggregation. With abruptly flowing with high shear rate, RBCs rapidly disaggregate and the intensity of the transmitted light becomes low. When continuously flowing with decreasing shear rate, RBCs tend to re-aggregate and the corresponding transmit-intensity gradually increases with time. The light intensity as a degree of RBC aggregation is plotted against shear rate and compared with blood viscosity. The advantages of this design are dual measurement at a time, simplicity, i.e., ease of operation and no moving parts, low cost, short operating time, and the disposable kit which is contacted with blood sample.
산업용 방열보호복의 인체공학 기능 점검에 관한 기초연구
박서원(Seowon Park),노호성(Ho seung Ro),이정진(Jung jin Lee),조진원(Jinwon Cho),박명수(Myungsu Park) 한국위험물학회 2021 한국위험물학회지 Vol.9 No.1
Industrial heat dissipation protective clothing is a protective equipment that protects workers from high heat in industrial sites that handle molten metals such as iron, copper, and aluminum. Existing protective clothing uses a multi-layered non-woven fabric as a base fabric for insulation performance, so it is heavy in weight and has disadvantages in terms of activity and comfort. The protective clothing under development is intended to enhance comfort by composing the fabric with a fiber composite structure that has been treated with a warp knitted structure (tricot) to increase comfort. To evaluate the workability of these protective clothing, ergonomic evaluation of ANNEX D of ISO 11612:2008 was performed. Each item was evaluated by performing visual inspection, wearing inspection, and behavioral inspection. The protective clothing under development was evaluated to be somewhat inconvenient when the range of motion is large, such as sitting or climbing stairs, and it is expected to be effectively used in suggesting improvement plans for new protective clothing.
안전한 웹 서비스를 위한 웹 어플리케이션 공격 유형 및 대응 방안 분석
이용호(Yongho Lee),박명수(Myungsu Park),윤준(Jun Yoon),윤정원(Jongwon Yoon) 한국정보보호학회 2004 情報保護學會誌 Vol.14 No.4
최근 정보통신 기술의 발달에 따라 인터넷을 통해 다양한 서비스를 제공하는 웹 서비스가 보편화 되고 있으며 이러한 웹 서비스를 가능하게 하는 핵심 요소가 바로 웹 어플리케이션이다. 웹 서비스는 이러한 여러 웹 어플리케이션들이 상호간에 유기적으로 통합되고 연동됨으로써 구성되어진다. 오늘날, 웹 서비스는 정치, 경제, 사회, 문화 등 모든 부분과 밀접하게 관련되어 우리 생활의 모습을 변화시켜가고 있다. 이에 따라 웹 어플리케이션 보안의 중요성이 부각되고 있으며 이에 대한 연구 개발이 필요하다. 본 고에서는 현재 웹 서비스의 해킹 현황을 살펴보고, 웹 어플리케이션 보안의 문제점과 널리 사용되고 있는 공격유형을 분석한다. 그리고 웹 어플리케이션을 공격으로부터 보호할 수 있는 대응 방안을 살펴본다.
Measurements of RBC deformability and its effect on blood viscosity
Yunhee Ku(구윤희),Myungsu Park(박명수),Sehyun Shin(신세현) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4
A slit-flow apparatus with laser diffraction method has been developed with significant advances in ektacytometry design, operation and data analysis. In the slit-flow ektacytometry (or laser-diffractometry), the deformation of red blood cells subjected to continuously decreasing shear stress in slit flow is measured. A laser beam traverses a diluted blood suspension flowing through a slit and is diffracted by RBCs in the volume. The diffraction patterns are captured by a CCD-video camera, linked to a frame grabber integrated with a computer, while the differential pressure variation is measured by a pressure transducer. Both measurements of laser-diffraction image and pressure with respect to time enable to determine deformation index and the shear stress. The range of shear stress of 0 ~ 35 ㎩ and measuring time is less than 2 min. When deforming under decreasing shear stress, RBCs change gradually from the prolate ellipsoid towards a circular biconcave morphology. The Deformation Index (DI) as a measure of RBC deformability is determined from an isointensity curve in the diffraction pattern using an ellipse-fitting program. The advantages of this design are simplicity, i.e., ease of operation and no moving parts, low cost, short operating time, and the disposable kit which is contacted with blood sample.
Optical Detection of Red Blood Cell Aggregation under vibration
장주희(Juhee Jang),박명수(Myungsu Park),구윤희(Yunhee Ku),신세현(Sehyun Shin) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.11
Aggregability of red blood cells (RBCs) was determined by a laser backscattering light analysis in a microfluidic channel. Available techniques for RBC aggregation often adopt a rotational Couette-flow using bob-and-cup system for disaggregating RBCs, which causes the system to be complex and expensive. A disposable microfluidic channel and vibration generating mechanism were used in the proposed new detection system for RBC aggregation. Prior to measurement, RBC aggregates in a blood sample were completely disaggregated by applying vibration-induced shear. With the present apparatus, the aggregation indexes of RBCs can be easily measured with small quantities of blood sample. The measurements with the present aggregometer were compared with those of LORCA and showed a strong correlation between them. The aggregability of the defibrinogenated blood RBCs is markedly lower than that of the normal RBCs. The noble feature of this design is the vibration-induced disaggregation mechanism, which enables to incorporate disposable element that holds the blood sample.
Red Blood Cell Deformability and its Hemorheological Consideration
구윤희(Yunhee Ku),장리쥬엔(Lijuan Zhang),박명수(Myungsu Park),신세현(Sehyun Shin),서장수(Jangsoo Suh) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.11
The suspension of hardened red blood cells (RBCs) differs from the suspension of normal RBCs with respect to their rheological behavior. The deformability of normal and hardened RBCs (obtained by heating blood at 49°C or by incubating RBCs in a solution of hydrogen peroxide) was measured with a slit diffractometer and RBC suspension viscosity was measured with a rotational viscometer. The peroxidetreated RBCs showed a significant decrease of the deformability and their suspension viscosity increased over a range of shear rates. The suspension viscosity of the heated RBCs, however, where the deformability is even lower than that of the peroxide-treated RBCs, was slightly higher than that of the normal RBC suspension in the high shear rates. The present study found that not all rigid cells cause an increase of blood viscosity at high shear rate, and therefore that decreased membrane deformability is not predictive of high-shear blood viscosity.