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소아의 에틸렌글리콜 및 메탄올 중독에서 Fomepizole의 효과
민하나 ( Ha Na Min ),황윤정 ( Yoon Jung Hwang ),고동률 ( Dong Ryul Ko ),주영선 ( Young Seon Joo ),공태영 ( Tae Young Kong ),좌민홍 ( Min Hong Choa ),박인철 ( In Cheol Park ),정성필 ( Sung Phil Chung ) 대한임상독성학회 2017 대한임상독성학회지 Vol.15 No.2
Purpose: The purpose of this study is to evaluate the effectiveness and adverse effect of fomepizole in the management of acute ethylene glycol or methanol poisoning in children. Methods: Databases such as PubMed, Embase, Cochrane library, and KoreaMed were searched using terms related to fomepizole, ethylene glycol, methanol and pediatric. All studies, regardless of study design, reporting effectiveness or safety endpoints in children were included. Reference citations from identified publications were reviewed. Only reports written in English or Korean languages were included. The reference search was performed by two authors. Results: Twenty-two relevant literatures were finally included. They were one narrative review, 4 retrospective case series, and 17 case reports (19 cases). Case reports were classified as 5 fomepizole only, 8 fomepizole with other therapies, and 6 no fomepizole. All patients from the literatures were fully recovered without long term sequelae. Adverse effects of fomepizole were reported including anaphylaxis, thrombophlebitis and nystagmus. Conclusion: There are insufficient literatures regarding fomepizole treatment in children with ethylene glycol or methanol poisoning. The benefits or harms are not clearly established based on the clinical evidences. More prospective comparative studies are required in the future.
연구논문 : 외식기업의 브랜드 다각화가 수익성에 미치는 영향에 관한 연구
민하나 ( Ha Na Min ),김인정 ( In Jung Kim ),최규완 ( Kyu Wan Choi ) 한국식생활문화학회 2014 韓國食生活文化學會誌 Vol.29 No.6
Brands play a critical role as a core asset and the primary driver for corporate growth because of their power of identity and influence on customers’ perceptions in restaurant industry. However, in spite of diverse and dynamically changing recent brand portfolio strategies of restaurants, a study on the effect of brand diversification on financial performance has been rarely conducted in the restaurant industry context. Considering competing viewpoints regarding diversification’s influence on financial performance, the purpose of this study is, therefore, to examine the effect of brand diversification on firm performance of restaurants. The results indicated that brand diversification is positive effect to profitability. Brand diversification seems to be attractive and might be a reasonable growth strategy to expand market power by satisfying diverse consumer needs. Therefore, restaurant managers should be consider in implementing brand diversification strategy especially in dynamically changing trend of brand diversification in the current restaurant industry.