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급성(急性) 신부전(腎不全)이 동반(同伴)된 근양사(筋壤死)에 있어서의 $^{99m}Tc$-MDP 골주사(骨走査)
문희범,한진석,김삼용,조보연,이정상,고창순,조경삼,Moon, H.B.,Han, J.S.,Kim, S.Y.,Cho, B.Y.,Lee, J.S.,Koh, C.S.,Cho, K.S. 대한핵의학회 1980 핵의학 분자영상 Vol.14 No.2
We studied four patients with muscle necrosis associated with acute renal failure to evaluate the diagnostic value of the bone scan in this disease. The illness followed carbon monoxide poisoning in two patients, acute physical exertion in one and contaminated intramuscular injection in the other. Whole-body rectilinear bone scans using technetium 99m-methyldiphosphonate were done. In all patients, increased muscle labelling at the regions of suspected muscle injury was showed, and in one, it was after normalization of serum muscle enzyme levels. In one patient, the bone scan was rechecked 8 months later and showed no residual abnormality. Above all, the site and precise extent of muscle injury could be detected and the degree of muscle labelling seemed to correlate with the severy of muscle injury. These findings suggest that isotope scanning may be useful in the diagnosis of patients with acute muscle necrosis.
한국인 류마티스 관절염 환자에서 질병 중증도 표지자로서의 HLA-DR4 유용성
임미경 ( M. K. Lim ),이창근 ( C. K. Lee ),최승원 ( S. W. Choi ),주용선 ( Y. S. Ju ),주유숙 ( Y. S. Cho ),김성문 ( S. M. Kim ),신명진 ( M. J. Shin ),오흥범 ( H. B. Oh ),유빈 ( B. Yoo ),문희범 ( H. B. Moon ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.1
Objective: To investigate HLA-DR4, its subtype and shared epitope as a severity marker in Korean patients with rheumatoid arthritis. Methods: One hundred thirty-six RA patients were typed for HLA DR4 and HLA-DRB1 alleles by the polymerase chain reaction-sequence specific probe method. The patients were retrospectively evaluated for extra-articular features, presence of remission, and joint failure. Bony erosion score was assessed by Sharp`s method with modification. Results: Patients with HLA-DR4 had significantly higher prevalence of extra-articular features compared to those without the allele. However, there was no association of HLA-DR4, HLA-DRB1*0405 and shared epitope with rate of remission, joint failure, and bony erosion score. Eighty-two percent of patients were rheumatoid factor positive. With seropositive patients only, the results were the same as those above. Conclusion: HLA-DR4, HLA-DRB1*0405 and shared epitope are not a severity marker in Korean patients with RA in terms of radiological score, rate of joint failure, and rate of clinical remission. Data from this study do not support the clinical use of HLA-DR4 typing as a prognostic marker in Korean patients with RA.
Tc-99m-albumin 혈관조영술로 진단한 간혈관종의 1예
고창순,최강원,윤휘중,문희범,권인순,김정용 대한핵의학회 1979 핵의학 분자영상 Vol.13 No.1
A case of hepatic hemangioma is presented in which blood pool imaging by Tc-99m-HSA provided a definite diagnostic clue. Cavernous hemangiomas are the most common benign tumor of the liver. But the majority of them are asymptomatic and are found incidentally at laparotomy or autopsy. Selective hepatic arteriogrophy has been the most helpful technique for the preoperative diagnosis. Recently radioisoeope scan and ultrasonogram proved to be a new, definite and non- invasive diagnostic procedure. $quot;