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        Development of the Parental Questionnaire for Cerebral Visual Impairment in Children Younger than 72 Months

        문진화,김건하,김성구,김승효,김영훈,김준식,김진경,노병호,변정해,염정숙,은백린,은소희,최지은,정희정 대한신경과학회 2021 Journal of Clinical Neurology Vol.17 No.3

        Background and Purpose Cerebral visual impairment (CVI) is an underdiagnosed condition in children, and its assessment tools have focused on older children. We aimed to develop a parental questionnaire for cerebral visual impairment (PQCVI) for screening CVI in young children. Methods The PQCVI comprised 23 questions based on a modified version of Houliston and Dutton’s questionnaire for older children. The PQCVI with neurocognitive function tests was applied to 201 child–parent pairs with typically developing children younger than 72 months (age 32.4±20.1 months, mean±standard deviation). The children were classified into six age groups. The normative data, cutoff scores, and internal reliability were assessed and item analysis was performed. We referred to the total score for all questions as the cerebral visual function (CVF) score. Results The normative data showed that the CVF score and the scores corresponding to ventral-stream and dorsal-stream visual functions plausibly increased with age. The scores rapidly reached 90% of their maximum values up to the age of 36 months, after which they increased slowly. Cronbach’s alpha for all questions across all age groups was 0.97, showing excellent consistency. The item difficulty and item discrimination coefficients showed that the questions were generally adequate for this age stage. Conclusions The PQCVI items produced reliable responses in children younger than 72 months. The rapid increase in scores before the age of 3 years supports the importance of early identification of CVI. Following additional clinical verification, the PQCVI may be useful for CVI screening.

      • 신생아 패혈증의 원인 및 항생제 감수성

        문진화,오성희,김학원,문수지,최태열,Moon, Jin Hwa,Oh, Sung Hee,Kim, Hak Won,Moon, Su Jee,Choi, Tae Yeol 대한소아감염학회 2002 Pediatric Infection and Vaccine Vol.9 No.2

        목 적: 본원 신생아실 및 신생아 중환자실에서 10년간 발생한 신생아 패혈증을 조사하여 환아들의 특징, 패혈증의 원인균 및 항생제 감수성의 변화를 파악하고 신생아 패혈증을 치료하는데 도움되고자 하였다. 방 법: 1989년부터 1998년까지의 10년간 본원 신생아실 및 신생아 중환자실에 입원하였던 환아 15,144명에 대해 의무기록을 확인하여 신생아 패혈증으로 진단된 환아를 선별하였다. 조사 기간을 1989년부터 1993년까지(전반기)와 1994년부터 1998 년까지(후반기)로 나누어 패혈증으로 진단된 환아 들의 임상적 특징, 균의 종류와 빈도, 항생제 감수성의 변화 양상을 관찰하였다. 결 과 : 신생아 패혈증은 총 15,144명 중 170명에서 진단되어 1.1%(전반기 91명, 1.2%, 후반기 79명 1.0%)이었으며, 186회(전반기 99회, 후반기 87회)에 걸쳐 200개의 균주(전반기 109균주, 후반기 91균주)가 분리동정 되었다. 평균 발병시기는 생후12.3일로 전반기 8.8일, 후반기 16.3일이었고, 조발형은 전반기 34.7%, 후반기 23.0%로 나타나 전반기에 더 빨리 발병하였다. 분리된 균주는 그람양성균 132회 (66.0%), 그람음성균 60회(30.0%), 진균 8회(4.0%)이었으며, Coagulase negative Staphylococcus(CNS)가 총 69회(34.5%)로 가장 많은 빈도를 나타내었고, Staphylococcus aureus(S. aureus) 36회(18.0%), Klebsiella pneumoniae(K. pneumoniae) 17회(8.5%), Enterococcus 12회(6.0%), Enterobacter cloacae(E. cloacae) 8회(4.0%), Escherichia coli(E. coli) 6회(3.0%), Pseudomonas aeruginosa(P. aeruginasa) 5회(2.5%) 등의 순이었다. 진균으로는 Candida parapsilosis, Candida albicans, Trichosporon pullulans 가 분리되었다. CNS, S. aureus 및 Acinetobacter baumannii(A. baumanii), Candida는 전반기에 비해 후반기에 더 많이 분리 동정되었으며, CNS 및 S. aureus의 methicillin 및 1세대 cephalosporin에 대한 항생제 감수성은 전반기에 비해 후반기에 감소하였고 aminoglycosides에 대한 감수성은 후반기에 증가하였으며, vancomycin 내성균은 분리되지 않았다. K. pneumoniae, Enterococcus, E. coli 및 P. aeruginosa는 전반기에 비해 후반기에 감소하였으며 K. pneumoniae는 1세대 cephalosporin에 대해 전, 후반기 모두 낮은 감수성을 보였고 tobramycin과 gentamicin에는 후반기에 감수성이 증가하였으며 amikacin, ceftriaxone, trimethoprim-sulfamethoxazole에는 전, 후반기 모두 높은 감수성을 보였다. Enterococcous는ampicillin, penicillin 및 1세대 cephalosporin에 대한 감수성이 후반기에 감소하였으나 vancomycin 내성균은 분리되지 않았다. 결 론 : 지난 10년간의 신생아 패혈증의 발생 빈도는 1.1%이었으며, CNS와 S. aureus가 신생아 패혈증의 주 원인균이었고, 일차 항생제에 대한 감수성은 전반기에 비해 후반기에 감소하였으나 vanco- mycin 내성균은 발견되지 않았다. 신생아 패혈증의 주요 원인균으로 알려진 group B Streptococcus는 발견되지 않았으며, K. pneumoniae에 의한 신생아 패혈증은 후반기에 더 많이 발생하였으나 항생제 감수성은 감소되지 않았다. Background : To delineate the changes in the causative agents of neonatal sepsis and their antimicrobial susceptibilities in the neonatal intensive care unit and nursery of Hanyang University Hospital during the past 10 years. Methods : Hospital records of 15,144 patients hospitalized at the NICU and nursery of Hanyang University Hospital from 1989 to 1998 were reviewed and neonates diagnosed of neonatal sepsis were sorted and included in the study. The study period was divided into Period A(the first 5 years) and Period B(the second 5 years) to analyse causative agents and their antimicrobial susceptibilities. Results : Neonatal sepsis was diagnosed in 170 patients(1.1%{Period A 1.2%, Period B 1.0%}) among the total of 15,144 inpatients. Two hundred isolates(Period A 109 isolates, Period B 91 isolates) were identified in 186 blood cultures(Period A 99 cultures, Period B 87 cultures) from 170 patients(Period A 91 patients, Period B 79 patients). The average age at the onset of the disease, when the initial blood culture was drawn, was 12.3 days old(Period A 8.8 days, Period B 16.3 days), and the proportion of the early onset disease was 34.7% in Period A and 23.0% in Period B, indicating that neonatal sepsis developed earlier during Period A. Among the isolated organisms including Gram positive bacteria[132(66.0%)], Gram negative bacteria [60(30.0%)], and fungi[8(4.0%)], coagulase negative Staphylococcus(CNS) was the most common organism(69/34.5%), followed by Staphylococcus aureus(36/18.0%), Klebsiella pneumoniae(17/8.5%), Enterococcus(12/6.0%), Enterobacter cloacae(8/4.0%), Escherichia coli(6/3.0%), and Pseudomonas aeruginosae(5/2.5%). The isolated fungi were Candida parapsilosis, Candida albicans, and Trichosporon pullulans. CNS, S. aureus and Acinetobacter baumannii were isolated more frequently in Period A compared to Period B. Antimicrobial susceptibilities of CNS and S. aureus to methicillin and the first generation cephalo sporins were decreased in Period B compare to Period A, those to aminoglycosides were increased in Period B, and vancomycin resistant strains were not identified. K. pneumoniae, Enterococcus, E. coli, and P. aeruginosa were isolated less frequently in Period B, compared to Period A. For K. pneumoniae, antimicrobial susceptibilities to the first generation cephalosporins were low in both Periods A and B, those to tobramycin and gentamicin were increased in Period B, and those to amikacin, ceftriaxone, and trimethoprim-sulfamethoxazole were high in both Periods A and B. Antimicrobial susceptibilities of Enterococcous to ampicillin, penicillin, and the first generation cephalosporins were decreased in Period B, but vancomycin resistant strains were not identified. Conclusion : The occurrence rate of neonatal sepsis during the past 10 years in the NICU and nursery of the Hanyang University hospital was 1.1%, and the most common causitive agents were CNS and S. aureus, to which the antimicrobial susceptibilities to the first line drugs decreased in the later half of the study period with no vancomycin resistant isolates identified. Group B Streptococcus known to be the most common agent causing neonatal sepsis was not identified, and K. pneumoniae was isolated more commonly during the later half of the study period without decreased antimicrobial susceptibilities.

      • 초극소 저출생 체중아에서 발생한 Listeria Monocytogenes에 의한 조발형 패혈증 1례

        문진화,오성희,문수지,Moon, Jin Hwa,Oh, Sung Hee,Moon, Soo Jee 대한소아감염학회 2000 Pediatric Infection and Vaccine Vol.7 No.2

        저자들은 재태기간 26주에 조기 진통으로 분만 후 사망한 초극소 저출생 체중아에서 L. monocytogenes에 의한 패혈증과 이에 의한 사망을 관찰하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Listeria monocytogenes is one of the important causes of neonatal sepsis and listerial neonatal infection manifests in two forms : Early-onset sepsis syndrome, associated with spontaneous abortion, still birth, preterm labor, granulomatosis infantiseptica, respiratory distress, sepsis, hemodynamic compromise and late-onset listerosis mainly associated with meningitis. Cases of neonatal listerosis reported in Korea have been rare and all were full term newborns. We, herein, report a case of early-onset sepsis due to L. monocytogenes in a extremely low birth weight infant who were born in a critical condition and succumbed in the second day of life despite the intensive care.

      • KCI우수등재

        인문,사회과학편 : 댄스스포츠 선수들의 파트너 신뢰가 팀 몰입 및 결속력에 미치는 영향

        문진화(JinHwaMoon),이근모(KeunMoLee),오세복(SeBokOh) 한국체육학회 2006 한국체육학회지 Vol.45 No.5

        댄스스포츠에 있어서 파트너는 경기력 향상 및 만족도에 영향을 미치는 가장 필수적 요소이다. 이에 본 연구는 댄스스포츠 선수들의 파트너 신뢰(Reliance)가 팀 몰입(Team Commitment) 및 결속력(Unity)에 미치는 영향관계를 구명하여 파트너와의 상호보완적 관계형성을 위한 연구에 의미 있는 기초 자료를 제공하는데 목적이 있다. 2006년 1월부터 2월까지 전국 댄스스포츠 선수권대회에 참가하는 16세 이상의 선수 316명을 대상으로 하였으며 SPSS 12.0 Program을 이용하였다. 자료의 타당도와 신뢰도를 검정하기 위한 탐색적 요인분석과 Cronbach's α계수를 이용하였고, 신뢰와 팀 몰입 및 결속력의 영향관계를 구명하기 위하여 회귀분석을 실시하였다. 회귀분석 결과 신뢰에 의한 팀 몰입의 설명력은 39%, 신뢰에 의한 결속력은 49%, 팀 몰입에 의한 결속력은 35%까지 설명하고 있었다. A partner in dance sport is the most important factor in improving the performance and satisfaction. Therefore, this study is to provide source material for the research on forming the complementary relationship between dance sport partners by looking into the effect of partner reliance on the team commitment and unity. It also provided the basic information to make effectively the reciprocal relationship for dance sport exert. The data was collected from 316 dance sport experts who were more than 16 age participating in the national championship of dance sport. SPSS ver 12.0 program was used for analyzing data. In order to investigate the validity and trust of data Exploratory factor analysis and Cronbach's α were calculated. Regression analysis was used to explain the relationship among reliance, team commitment and unity. The conclusions were as follows: The reliance of partner had an effect on team commitment and unity. Team community also influenced team unity.

      • 뇌실 - 복강 단락술과 횡경막하 농양에 의한 흉막 삼출 1 예

        문진화(Jin Hwa Moon),이수용(Soo Yong Lee),오재원(Jae Won O),이하백(Ha Baik Lee) 대한소아알레르기호흡기학회 1999 소아알레르기 및 호흡기학회지 Vol.9 No.3

        Several different diseases may have an associated exudative pleural effusion. In a patient with a pleural effusion of unknown origin, a possibility of intra-abdominal abscess should always be considered, especially in a patient who has the past history of abdominal surgery or procedure. We describe a 5-year-old male patient who had been operated for congenital hydrocephalus with ventriculo-peritoneal shunt insertion at 15 months old, admitted to our hospital with complaints of headache and edema of valvular area. Brain CT scan revealed shunt disconnection, and he was operated for insertion of new shunt catheter. Seven days after first operation, he presented fever, abdominal pain and distension. Abdominal ultrasonography revealed bowel adhesion and peritonitis. Staphylococcus epidermidis was isolated by aspiration of shunt valve and reservior, repeatedly. He should have had another 2 operations of peritoneal lavage and catheter change for shunt infection associated peritonitis. Eight days after the 3rd operation, he complained newly developed left shoulder, left chest pain and fever up to 39℃. His chest x-ray revealed pleural effusion on the left side. Though antibiotic therapy was already being conducted, the left pleural effusion and fever aggravated. Repeated ultrasonography disclosed an occult left subphrenic abscess, explaining the fever and left pleural effusion on the radiograph. Fourth operation of abscess drainage and infected shunt removal with extraventricular drainage was done. After the operation, his fever and pleural effision were rapidly disappered, and postoperative CSF culture was negative. A review of ventriculoperitoneal shunt infection associated with subphrenic abscess and pleural effusion was discussed.

      • KCI등재

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