완전 뇌하수체 적출이 부신에 미치는 영향에 관한 연구

문명선 최신의학사 1974 最新醫學 Vol.17 No.8

The purpose of this study is to present the histological effects on the adrenal gland following a new method of total hypophysectomy in the dog. In this study nineteen adult mongrel dogs, weighing from 7 to 10 kg, were used. Eleven of them were male and eight were female. A newly devised operative method is as follows: Under pentobarbital sodium, 30 mg/kg body weight, intravenous anesthesia the dog was _ placed on the operating table in prone position, and a tube, about 5 cm in diameter, was inserted in the 'mouth to displace the mandibular angle anterodo?wnwardly. A vertical incision from the midline to just behind the mandibular angle was made on the right side and the temporal muscles were also incised vertically, and retracted these to expose the temporal bone. Following wide craniectomy down to the base of the middle cranial fossa and dural incision, temporal lobe was elevated at the tip of the middle cranial fossa with narrow brain retractor. Since this approach was deep and narrow, a brilliant illumination was thrown from head lamp at the center of binocular magnifier. As the third cranial nerve and internal carotid artery were exposed, arachnoid membrane was torn and aspirated cerebrospinal fluid slowly to obtain wider exposure, then elevated posterior communicating artery to expose the pituitary body and stalk. The stalk was clipped or crushed with microforceps and sectioned with microscissors, then pituitary body was isolated with microelevator and removed in a piece. The wound was closed in layers. Among these experimental aniamls, 6 dogs were observed for the period of 43-77 days, and in 6 dogs dexamethasone was given intramuscularly for one or two weeks, the rest 7 were not al control group. Following clinical observation, these animals were sacrificed with intracarotid arterial infusion of 10% neutral formalin solution and removed the brain and adrenal gland, and fixed. iii 10% neutral?formalin solution. Theremoved brain was examined and the adrenal gland was stained with hematoxylin-eosin, periodic acid Schiff (PAS) and Toluidine blue staining methods. The observed results were as follows: 1. Adrenal cortical thickness in normal control dogs measured 1.03 mm, which decreased to 0.58 mm (56.3% of control group) following hypophysectomy. With administration of dexamethasone for 1 to 2 weeks, cortical width measured 0.85 mm and .0.56 mm, respectively. 2. The decrease of cortical thickness in hypophysectomized dogs? was interpreted as a consequence of atrophy, being much profound in the zonae fasciculata and reticularis. Proportional thickness of both zonae fasciculata and reticularis was 83.6% in normal control group, but decreased to 73.8% follo?wing hypophysectomy. With administration of dexamethasone, figures of 75.1% and 64.1% reflected similar reduction as in overall cortical thickness. 3. Those cortical alterations proved to be the results of cytolysis, atrophy and fat depletion of cortical cells, being more prevalent in the zona reticularis. Modification of histological changes following dexamethasone administration was only slight increase of width in zona fasciculata, but reticular zone underwent progressive reduction. 4. Atrophic changes in zona glomerulosa was not remarkable but appeared in relative increase. Effect of administration of dexamethasone accentuated slightly the width of the zona glomerulosa. 5. No significant alterations were found in medullary tissue regardless the type of procedures. 6. Mast cells, distributed normally in the capsule and periadrenal adipose tissue, zona fasciculata and medulla in order, disappeared from the all layers following hypophysectomy, but restored by administration of dexamethasone especially in zona reticularis. The above experimental features indicated that adrenal cortical atrophy following hypophysectomy was the cytologic reflection of cytolysis, atrophy and fat depletion in zonae fasciculata and reticulasis.' Administration of dexamethasone disclosed a tendency of suppression of cortical atrophy in the early phase, but the cortex eventually undergwent atrophy as well as similar features in mast cells.

조용기 목사의 오순절적 생명의 성령론

문명선 한세대학교 영산신학연구소 2012 영산신학저널 Vol.26 No.-

This article will examine the pneumatology of Dr. David Yonggi Cho in three distinct areas: (1) His ideas on the doctrine of the Trinity, (2) His ideas on a personal relationship with the Holy Spirit, (3) His ideas on church growth and the external ministry of Yoido Full Gospel Church by the grace of the Holy Spirit. Actually, Jürgen Moltmann was the first person to observe that the theology of Dr. David Yonggi Cho is the Pentecostal theology of life. So the aim of this article is to expand upon this idea and provide evidence to support that the pneumatology of Dr. David Yonggi Cho is indeed a Pentecostal pneumatology of life. Through these three filters above, it will be made clear that the pneumatology of Dr. David Yonggi Cho is a Pentecostal pneumatology of life. First, the personal relationship among the three persons of the Godhead shows the true relationship of life in that there was and always will be a personal relationship between the members of the Godhead, and therefore, there is always a relationship of life. Moreover this personal relationship in the Godhead has been extended to the children of God in that they now have a direct and personal relationship with the Holy Spirit. Since the time of the New Testament all children of God can have a personal relationship of life with God because the Holy Spirit came upon His disciples on the day of Pentecost. And lastly, the Pentecostal pneumatology of life was evidenced in the external ministry of Yoido Full Gospel Church through the social gospel. This ministry, with the help of the Holy Spirit working with the children of God, brought life to many areas of the culture where the power of death was threatening the people. The bottom line is that when the Holy Spirit moves, there is fullness of life. This was certainly the case with Yoido Full Gospel Church. In conclusion this is why the pneumatology of Dr.David Yonggi Cho is a Pentecostal pneumatology of life. 이 논문은 조용기 목사의 성령론을 세 가지 영역에서 연구한 것이다: (1) 삼위일체론적 측면, (2) 성령님과의 인격적인 교제에 관한 측면, (3) 교회성장과 여의도순복음교회의 대외적 사역에 관한 측면. 조용기 목사의 신학을 오순절적 생명의 신학이라고 표현한 신학자는 위르겐 몰트만 박사가 처음이다. 이와 관련하여 이 논문의 목적은 조용기 목사의 성령론이 오순절적 생명의 성령론으로 표현될 수 있는지를 살펴보는 것이다. 앞에서 제시한 세 가지 영역에서의 연구를 통해서 조용기 목사의 성령론이 다음의 설명과 같이 오순절적 생명의 성령론이라 표현될 수 있다는 것이 분명하게 드러났다. 우선, 조용기 목사의 성령론에 있어서, 삼위일체 하나님의 각 인격체들 사이의 관계가 항상 생명의 관계임이 분명하게 드러난다. 그뿐만 아니라, 삼위일체의 관계성에서 드러난 인격적인 교제는 하나님의 자녀들에게로 확장된다는 것이 조용기 목사의 성령론에서 드러난다. 오순절 성령강림을 통해서 성령님을 통한 하나님과의 인격적인 교제가 제사장의 영역에서 모든 하나님의 자녀에게로 확장되었다는 것을 알 수 있다. 마지막으로, 오순절적 생명의 성령론은 구제와 사회구원을 통해서 이루어진 여의도순복음교회의 외적인 사역을 통해서 드러났다. 이러한 구제사역은 하나님의 자녀들을 통해서 역사하시는 성령님의 도우심을 통해서 이루어진 것이다. 여의도순복음교회는죽음의 힘이 역사하는 문화의 영역에 생명을 가져다 주는 사역을 통해서 위협받는 사람들을 도와주고 있다. 성령님의 운행하심이 있는 곳에는 충만한 생명력이 역사한다는 사고가 앞에서 전개한 사상의 배경이다. 결국 조용기 목사의 성령론은 오순절적 생명의 성령론이라 말할 수 있다.

칼빈의 신학에 있어서 성례전의 의미

문명선 연세대학교 신과대학 2009 신학논단 Vol.56 No.-

Some theologians consider Calvin "the theologian of sacraments". There may be a few sentences in his Institute that could mislead us to regard Calvin as a theologian who has no great interest in the sacraments. However, Calvin's teaching on the sacraments is one of the central theological themes in his theology as the relationship between God and man plays such an important part in it. Calvin insists in his Institute that Christians can experience the close relationship in the sacraments. There are two close relationships between God and man in the sacraments: a) spiritual growth m Jesus Christ, b) oneness with Jesus Christ.

인격주의 신학에서 본 인격의학의 이해 : 하인리히 오트와 폴 투르니에를 중심으로 By the viewpoint of Paul Tournier and Heinrich Ott

문명선 통합연구학회 1998 통합연구 Vol.11 No.1-2

Religion is necessary for those who live today. Each one has his own belief in god. Everywhere people seek supernatural powers when they realize their limits. This is the basis for religion. In religion, we can think of God. and we should meet the true God in our faith and begin to grow. Prayer is necessary to meet God. In this, Heinrich Ott said in his Theology that prayer is the method to belief itself. Because of the theology, he put forth about developing personal relationship with God. He was effected by personal philosophy of Martin Buber. In these beliefs Heinrich Ott was called a personalistic Theologian. Heinrich Ott highly valued prayer which is communication with God. A doctor named Paul Tournier initiated a theory about the medical science and prayer. He encouraged the patient to change their thoughts about healing - not just looking at medical treatment, but to be healed through faith in God through prayer as well. This was a new movement in those days. In this movement, the theory between theology and medical science become quiet pervasive. The teachings of paul Tournier were called Medicine of Person. In this beliefs, Medicine of Person of Paul Tournier recognizes and emphasizes a personal relationship between medical doctors and patients, and patients and God. Paul Tournier was influenced by the personal philosophy of Martin Buber. As shown above, Heinrich Ott and Paul Tournier had similar backgrounds in that both of theorists accepted the personal prayer by Martin Buber. They also emphasized prayer on their studies. Prayer is communication with God himself ; it helps to develop all aspects of science. Therefore, in medical science prayer can help heal mental sicknesses and sufferings beyond medical treatment. And even more in theology prayer has the powerful function of communication with God and helps people get to know God better and shows us who really God is. Therefore, understanding human beings and prayer makes possible the relationship between Personalistic Theology and Medicine of Person.

뇌출혈을 동반한 소아 뇌종양 : 1예 보고 Report of one case

김순기,문명선 대한신경외과학회 1984 Journal of Korean neurosurgical society Vol.13 No.3

We report a rare case of brain abscess associated with intracerebral hematoma in a child, at the age of 3. A 3 years old female child has been suffered from the cellulitis with pustule on her right leg since 3 weeks before, which has aggravated gradually, and developed acute bacterial meningitis for 2 weeks before transfer to Department of Neurosurgery. The acute bacterial meningitis has been treated for 2 weeks in Pediatric Department. The brain CT revealed a small brain abscesses in the occipital region bilaterally. With methicillin, the clinical progress including C.S.F. findings has got improvement, which has been almost complete. We found the staphylococcus from the pustule on her right leg by smear and culture. At that time, 3 weeks since the onset, suddenly vomiting, consciousness change (drowsy to semicomatose), left hemiparesis developed. Immediate brain CT revealed multiple abscess in both occipital poles with bulky intracerebral hematoma in right perieto-occipital region. Immediate craniectomy was performed for removal of intracranial hematoma, which was ca 50cc in amount, at first, and bilateral trephination with aspiration and drainage for the multiple brain abscess at second. The postoperative course was satisfactory with mannitolization and antibiotic treatment. The recovery was dramatic one.

신경외과에서의 흉추 및 요추골골절의 해링톤씨봉 고정 : Clinical Study

최문배,문명선 대한신경외과학회 1985 Journal of Korean neurosurgical society Vol.14 No.2

Harrington Instrumentation to treat the unstable fracture (including the fracture dislocation) of the thraco-lumbar spine with neurologic deficits is a very effective method. This method provides rigid fixation and stability for thoracolumbar fracture, also offers the optimum condition for recovery of nerve roots, and decompresses the spinal canal with anatomical reduction. The principal advantage for this method of treatment is the early mobilization of the patient and enhanced rehabilitation. Authors, performed Harrington Instrumentation with a laminectomy experienced 20 cases of unstable thoraco-lumbar spine fracture (including the fracture-dislocation) with neurologic dificit from Aug. 1980 to Oct. 1984. The following results were obtained: 1) Of twenty patients, the patients at the age 20 to 49 were most commonly injured and predominant cause of spinal injury was falling accident. 2) The thoraco-lumber fracure( including fracture-dislocation) were thoracolumbar junction, the commonest site among them was the 1st number vertebra, and the commonest mechanism of spinal injury way flexon iniury. 3) Most commonly, paraplegia was with twelve thoracic vertebra injury, and paraparesis was with 1st lumbar vertebra. 4) Correction of the kyphotic deformity was 8 degree on the average, and the range of the correction was between 0 degree and 19 degree. 5) Neurological recoveries were gained from 14 patients (70%), and the l0 patients (50%) among them were completely recovered. 6) Average hospital periods were 78 days and after an average 21 postoperative days, ambulation was started. 7) In complication, three hook dislocations were occured. 8) Early operation (laminectomy for posterior decompression and Harrington Instrumentation for anterior decompression) was very effective in spinal cord injury.

다발성 수막종 : 1예 보고 Case Report

李承洙,孫孝正,文明善 대한신경외과학회 1979 Journal of Korean neurosurgical society Vol.8 No.1

Despite of their frequent occurrence among the brain tumor, meningiomas are rarely seen as a multiple growth, and the incidence of multiplicity in meningioma is about 2%, except for 6.7% in Horrax' series. The anthors report a case of multiple meningiomas without evidence of von Recklinghausen's disease. The patient had suffered from the headache, chocked disc and right hemiplegia for about two years which had been aggravated in these two weeks before admission. Left carotid angiogram revealed as a parasagittal giant meningioma. On operation, we did not remove single giant meningioma, but six lumps of mass variably sized from walnut to hen egg, with success. The postoperative course was uneventful and the recovery from hemiplegia was dramatic.

석회화를 동반한 소아만성 경막하 혈종 : 증례보고 Case Report

류연석,김순기,문명선 대한신경외과학회 1986 Journal of Korean neurosurgical society Vol.15 No.2

Intiacianial calcification is relatively common, but calcification of chronic subdural hematoma is rare condition. Nevertheless, already in 1884 Von Rokitansky had described a calcified chronic subdurel hematoma found at autopsy. Subsequently Lewis(1889), Elsner(1896), and 0'sullivan(1925) mentioned calcification of intracranial hematoma. In 1930, Goldham reported the first case treated by operation. A 15-year-old Korean male was admitted to this hospital because of a episode of generalized epileptic seizure, one day before admission. Past history was unknown about head injury and his past birth condition. Patient has complained weakness of right upper and lower extremity since his infant. Neurological examination revealed the left hemiparesis, but others were normal. Skull X-ray films showed dense conglomerated calcific density with surrounding rim like lucency in left fronto-parietal region. Left carotid angiogram revealed no abnormalities except hypoplasia of left hemisphere. Brain computed tomogram demonstrated hyperdense subdural mass surrounding decreased parenchymal density in left fronto-parietal region. A craniectomy was performed for removal of the calcified mass. A oval concaved bony hard mass was found in subdural space. The calcified bony hard mass was adherent with the surface of cortex by loose connective tissue. We removed the bony hard mass completely. The postoperative course was very satisfactory and seizure has not been appeared after discharge. Microscopic findings demonstrated ossification and fibrosis, consisting with old hematoma which showed up a calcification of chronic subdural hematoma.

하반신마비를 동반한 흉추 Ewing's Sarcoma : 1예 보고 Report of 1 case

유영만,이광영,문명선 대한신경외과학회 1982 Journal of Korean neurosurgical society Vol.11 No.3

Since Ewing has reported a primary malignant tumor as medullary origin in 1921, the Ewing's sarcomas have been reported more than 1,000 cases in the literatures. The Ewing's sarcoma has frequent incidence in the long tubular bone but very rare in the skull and spine for primary malignant tumor of the bone. The incidence of the Ewing's sarcoma in the spine is very rare than in the skull. We experienced a case of Ewing's sarcoma of the thoracic spine which has associated a paraplegia as neurological deficit. A 24 years old Korean female has admitted to our clinic because of paraplegia with incontinence for 2 days. On admission, the neurological examination revealed a paraparesis below T3 level with urinary and fecal incontinence, and then local tenderness on T2 level. No fever and leucocytosis were checked. Only the ESR has elevated up to 38㎜/hr. The simple X-ray film of the thoracic spine has showed a mottled destruction of the T2 vertebral body and abscence of the pedicle shadow, which were more similar to the picture of malignant tumor(primary or metastatic) than the bony change of ostemyelitis. We performed a myelography by pantopaque through the lumbar and cisternal puncture for accurate site of lesion. We found a complete block at T2 level by myelography. Then the immediate total laminectomy on T2-3 was applied. The operative finding was a extradural mass, which has compressed the spinal cord. We removed the tumor mass incompletely but the decompression was enough. The neurologic deficit has improved gradually for post-operative 2 weeks, but the improvement of neurologic deficit has stopped to T10 sensory recovery. We performed a radiation therapy as 4500 rads dose for 4 weeks, but no further improvement has been found. The post-operative pathological diagnosis was Ewing's sarcoma as a anaplastic small cell type.

삼차신경초종의 1예

조병규,김국기,문명선,채진,최길수,심보성 대한신경외과학회 1974 Journal of Korean neurosurgical society Vol.3 No.1

Trigeminal neurinoma is a rare condition arising from the gasserian or trigeminal nerve root. It comprises 0.2% of all brain tumors, and usually affects middle life, but about 10% of it appears in adolescents. Middle fossa syndrome, symptoms and signs of cerebellopontine angle tumor and mixture of these may to developed through the extension of the tumor. Symptoms and signs of cerebellar and midbrain compression may also be elicited in some stage of the tumor. Erosion of the anteromedial portion of the petrous apex and defect of the floor of the middle fossa contribute to the diagnosis. Air studies and cerebral angiography have been used, and recently pantopaque basal cisternography has been introduced. The route of operation depends upon the main localization of the tumor, but transtemporal approach with tentorial section is widely used for dumbbell-shaped tumor. A case of cerebellopontine angle tumor which had been postoperatively proved to be a trigeminal neurinoma is reported.