환경조건 및 침자극에 따른 인체 생물 광자 방출량 변화에 관한 연구

류연희(Ryu yeonhee),정상용(Jung Sangyong),황혜숙(Hwang Hyesuk),김유성(Kim Yoosung),이영섭(Lee Youngseop),양은진(Yang Eunjin),최선미(Choi Sunmi) 한국한의학연구원 2008 한국한의학연구원논문집 Vol.14 No.2

Objective: Recently biophysical research has shown very weak radiation of photons in plant, animal and human cells. Biophoton emission of the aliving system has received specific phenomena because of its scientific potential for monitoring metabolism to human body. This paper proposes a new challenge possibility of the biophoton emission in biophysiological human condition index. Method: Biophoton emission were measured with twenty one healthy volunteers. The study analyses existence for the effect of specific acupoint stimulus, exposure to the sun and low temperature in healthy volunteers. Two photomultiplier tubes which spectral range was from 300 ㎚ to 650 ㎚ was used for the detection of biophoton emission observation of possible acupuncture stimulation effect at left hand palm. Result : There was a reversion of relative emission rates from the palms affected the environment condition. Otherwise, when the acupuncture stimulation, the emission rate was not enough significantly change(p<0.05). Conclusion: In this study, biophoton emissions depend on the environment condition for all subjects. Measurments with the biophoton emission rate analysis might be much considered in future studies.

자바스크립트의 이벤트 동작 분석을 위한 이벤트 모델링

류연희(YeonHee Ryou),류석영(Sukyoung Ryu) 한국정보과학회 2015 한국정보과학회 학술발표논문집 Vol.2015 No.6

자바스크립트의 이벤트 동작 분석을 위한 이벤트 모델링

류연희(Yeonhee Ryou),류석영(Sukyoung Ryu) 한국정보과학회 2015 정보과학회 컴퓨팅의 실제 논문지 Vol.21 No.12

자바스크립트 프로그램의 많은 경우가 이벤트 중심의 프로그램(event-driven program)으로, 사용자의 입력을 받아 실행하는 이벤트 함수를 매우 많이 사용한다. 따라서, 이벤트 중심의 자바스크립트 프로그램을 정적으로 분석하려면 이벤트가 어떻게 발생하고 동작하는 지를 분석할 수 있어야 한다. 본 논문에서는 자바스크립트 프로그램에서 이벤트의 발생과 동작을 정적으로 정확하게 분석하기 어려운 이유를 확인하고, 이벤트 중심 프로그램을 효과적으로 분석하기 위해 이벤트를 효율적이고 정확하게 나타낼 수 있는 이벤트 모델 기법을 제시한다. Many JavaScript programs are event-driven in the sense that they heavily use event functions that take user inputs to manipulate program behaviors. Thus, in order to statically analyze event-driven JavaScript programs effectively and precisely, static analyzers should be able to understand and precisely analyze the behaviors of events in terms of how they are created and evaluated. In this paper, we describe several reasons why static analysis of event behaviors in JavaScript programs is particularly difficult, and present a new event modeling mechanism that can represent behaviors of events precisely and efficiently for effective analysis of event-based JavaScript programs.

아시혈의 의미와 특성의 이해

이서영,류연희,이인선,채윤병,Lee, Seoyoung,Ryu, Yeonhee,Lee, In-Seon,Chae, Younbyoung 경락경혈학회 2022 Korean Journal of Acupuncture Vol.39 No.3

Objectives : Acupoints are divided into three categories: classical acupoints, extra-acupoints, and Ashi points. The aim of this study was to understand the meaning and features of Ashi points. Methods : We examined the original meaning of Ashi points from the classical medical texts, including the Beijiqianjinyaofang, the Essential Prescriptions Worth a Thousand Gold for Emergencies, and the Huangdi Neijing, the Yellow Emperor's Canon of Internal Medicine. Results : First, the Ashi method is to locate the points for the acupuncture and moxibustion based on the patients' reactions mainly manifested by sensations of comfort and pain, which can help identify not only Ashi points but also classical and extra-acupoints. Thus, Ashi points may or may not match to classical or extra-acupoints, and we propose that Ashi points should not be classified mutually exclusive to classical or extra-acupoints. Second, there are several similarities between Ashi points and myofascial trigger points. They are located by palpation and have no fixed anatomical positions. Patients experience painful but pleasant feeling when Ashi and myofascial trigger points are pressed, and stimulation of these points have treatment effects. Conclusions : We suggest that Ashi method be used to identify the acupoints based on how patients react when these points are pressed. Ashi points may or may not correspond to classical or extra-acupoints, and share traits with myofascial trigger points.

데이터마이닝을 이용한 동의보감에서 경락의 주치특성 분석

채윤병,류연희,정원모,Chae, Younbyoung,Ryu, Yeonhee,Jung, Won-Mo 경락경혈학회 2019 대한침구의학회지 Vol.36 No.4

Objectives : DongUiBoGam is one of the representative medical literatures in Korea. We used text mining methods and analyzed the characteristics of the indications of each meridian in the second chapter of DongUiBoGam, WaeHyeong, which addresses external body elements. We also visualized the relationships between the meridians and the disease sites. Methods : Using the term frequency-inverse document frequency (TF-IDF) method, we quantified values regarding the indications of each meridian according to the frequency of the occurrences of 14 meridians and 14 disease sites. The spatial patterns of the indications of each meridian were visualized on a human body template according to the TF-IDF values. Using hierarchical clustering methods, twelve meridians were clustered into four groups based on the TF-IDF distributions of each meridian. Results : TF-IDF values of each meridian showed different constellation patterns at different disease sites. The spatial patterns of the indications of each meridian were similar to the route of the corresponding meridian. Conclusions : The present study identified spatial patterns between meridians and disease sites. These findings suggest that the constellations of the indications of meridians are primarily associated with the lines of the meridian system. We strongly believe that these findings will further the current understanding of indications of acupoints and meridians.

침자 보사에서 자침 자극 강도의 특성

윤다은,장우창,류연희,이인선,채윤병,Yoon, Da-Eun,Jang, Woochang,Ryu, Yeonhee,Lee, In-Seon,Chae, Younbyoung 경락경혈학회 2022 Korean Journal of Acupuncture Vol.39 No.3

Objectives : The purpose of this study was to characterize the stimulation intensity in acupuncture manipulation techniques for tonification and sedation therapy. Methods : To describe the level of stimulation used in acupuncture manipulation techniques for tonification and sedation therapy, we reviewed the acupuncture manipulation techniques described in classical medical textbooks. Results : Based on the patients' conditions and pattern identification, acupuncture manipulation strategies for tonification and sedation therapy were chosen. For example, the excess condition was treated with sedative therapy, and the deficiency condition was treated with tonification therapy. For tonification therapy, weak to modest stimulation was applied in acupuncture manipulation techniques, whereas intense stimulation was applied for sedative therapy. Even though the intensity of acupuncture stimulation was chosen based on the clinical examination, deqi sensation is a crucial component of acupuncture treatment, and during acupuncture practice, the practitioner should choose the right intensity of acupuncture stimulation based on deqi response in each patient. Conclusions : We concluded that the tonifying and sedative effects of acupuncture treatment are related to the stimulation intensity of acupuncture manipulation techniques. For individualized medicine, the right amount of acupuncture stimulation should be administered based on the patients' conditions and responses, such as deqi responses.

수지부 정혈과 십선혈의 관계에 대한 고찰

윤다은 ( Da-eun Yoon ),류연희 ( Yeonhee Ryu ),이인선 ( In-seon Lee ),채윤병 ( Younbyoung Chae ) 경락경혈학회 2023 Korean Journal of Acupuncture Vol.40 No.1

Objectives : Our goals were to examine how the well points in the fingers came to be and how their placements have changed, as well as to determine how they relate to the EX-UE11 points. Methods : We reviewed the classic textbooks to understand the origin and the changes of locations of the well points in the fingers. We also compared the location and indications between well points in the fingers and EX-UE11 points. Results : At first, the tips of the fingers, which are now thought to be the locations of EX-UE11 points, were once described as containing well points. Currently, well points are positioned 0.1 F cun distal-medial (or lateral) to the medial (or lateral) corner of the nail. In addition to the locational commonality, we found similarities between the well points in the fingers and the EX-UE11 points in terms of their indications; for example, bloodletting at these places is frequently utilized to treat emergencies, including acute stroke and fever. Conclusions : We suggest that it is highly likely that well points in the fingers and EX-UE11 points were initially the same acupuncture point and later classified into two different acupuncture points, given their identical locations and indications. If the clinical relevance between the change process of the well points’ locations in the fingers and the EX-UE11 is studied in the historical literature, it is anticipated that the significance and clinical application of well points can be expanded.

훈침의 미주신경 실신 측면으로 이해와 적절한 예방과 조치

이서영 ( Seoyoung Lee ),류연희 ( Yeonhee Ryu ),이인선 ( In-seon Lee ),채윤병 ( Younbyoung Chae ) 경락경혈학회 2023 Korean Journal of Acupuncture Vol.40 No.4

Objectives : Needle sickness is one of the adverse events of acupuncture, although substantial adverse effects during a routine acupuncture treatment seem to be highly unusual. In this work, we propose that an acupuncture-related vasovagal response resembles needle sickness during acupuncture therapy. Methods : In this article, we discussed the general characteristics of vasovagal syncope and went into more detail on vasovagal syncope in people who have a fear of blood injection and injury. We also offer a recommendation for the prevention and management of vasovagal syncope brought on by acupuncture. Results : The vasovagal reaction related to acupuncture is closely associated with needle sickness. The prevention can be done using PEACHES (position, experience, anxiety, constitution, hydration, environment, symptom recognition) principles. The management should be conducted using the RIPCORD (recognize, initiate, position, communicate, order treatments, reassess, document) techniques. Conclusions : It is important to comprehend the characteristics of needle sickness as a vasovagal reaction related to acupuncture. According to the recommendation, practitioners should effectively prevent and manage needle sickness.

데이터 마이닝을 이용한 임상연구 데이터베이스 기반 원혈의 주치 특성

최다현 ( Dha-hyun Choi ),이서영 ( Seoyoung Lee ),이인선 ( In-seon Lee ),류연희 ( Yeonhee Ryu ),채윤병 ( Younbyoung Chae ) 경락경혈학회 2021 Korean Journal of Acupuncture Vol.38 No.2

Objectives : Source acupoint is one of the representative acupoints to treat various diseases in each meridian. We aimed to identify the patterns of selection of Source acupoints and their associations with diseases using clinical trials data. Methods : We extracted the frequency of Source acupoints across 30 diseases from clinical trials database. Acupuncture treatment regimens were retrieved from the Cochrane Database of Systematic Reviews. The frequency of Source acupoint use was calculated as the number of studies using a certain acupoint divided by the total number of included studies. Using hierarchical clustering and multidimensional scaling, the characteristics of Source acupoints were analyzed based on the similarity of the relationships between the Source acupoints and the diseases. Results : A total of 421 clinical trials were included for this analysis. LR3, HT7, KI3, and LI4 acupoints were most frequently used for the treatment of 30 diseases. Cluster analysis showed that LR3 and LI4 acupoints were grouped together and HT7 and KI3 acupoints were grouped together. Multidimensional scaling revealed that LR3, LI4, HT7, and KI3 acupoints have intrinsic properties in the two-dimensional space. Conclusions : The present study identified the selection patterns of the Source acupoints using clinical trials data. Our finding will provide the understanding of the characteristics of Source acupoints.

데이터마이닝과 네트워크분석을 통한 팔맥교회혈의 배합 패턴 연구

권민정 ( Min-jeong Kwon ),윤다은 ( Da-eun Yoon ),문희영 ( Heeyoung Moon ),류연희 ( Yeonhee Ryu ),이인선 ( In-seon Lee ),채윤병 ( Younbyoung Chae ) 경락경혈학회 2023 Korean Journal of Acupuncture Vol.40 No.4

Objectives : One of the crucial combinations of acupoints for treating various disorders involves the Eight Confluent acupoints. The present study aims to investigate the selection patterns of the Eight Confluent acupoints in clinical trials and determine the most frequent pairings through network analysis. Methods : The frequencies of the Eight Confluent acupoints were extracted from the Acusynth database, which includes data from 421 clinical investigations. We examined the degree distribution, eigenvector centrality, proximity centrality, and betweenness centrality of these acupoint combinations using network analysis. Results : Data mining revealed that among the Eight Confluent acupoints, PC6 and TE5 were the most commonly applied in the treatment of 30 disorders. Additionally, we identified the most frequently co-occurring pairs of Eight Confluent acupoints by network analysis which included PC6-GV20, SP4-GV4, LU7-LI4, TE5-PC7, GB41-SP6, KI6-BL62, and SI3-BL62. Conclusions : Through the application of data mining and network analysis, we have elucidated the selection patterns and combinations of the Eight Confluent acupoints. These findings provide valuable insights that can enhance doctors’ understanding of clinical databasedriven Eight Confluent acupoint selection patterns.