Emerging Paradigm of Crosstalk between Autophagy and the Ubiquitin-Proteasome System

남태욱,한종현,Sushil Devkota,이한웅 한국분자세포생물학회 2017 Molecules and cells Vol.40 No.12

Cellular protein homeostasis is maintained by two major degradation pathways, namely the ubiquitin-proteasome system (UPS) and autophagy. Until recently, the UPS and autophagy were considered to be largely independent systems targeting proteins for degradation in the proteasome and lysosome, respectively. However, the identification of crucial roles of molecular players such as ubiquitin and p62 in both of these pathways as well as the observation that blocking the UPS affects autophagy flux and vice versa has generated interest in studying crosstalk between these pathways. Here, we critically review the current understanding of how the UPS and autophagy execute coordinated protein degradation at the molecular level, and shed light on our recent findings indicating an important role of an autophagy-associated transmembrane protein EI24 as a bridging molecule between the UPS and autophagy that functions by regulating the degradation of several E3 ligases with Really Interesting New Gene (RING)-domains.

천도교 평화통일이념에 관한 논구

남태욱 경기대학교 민족문제연구소 2010 민족사상연구 Vol.19 No.-

[총설] Microbiome 기반 신약 개발 동향

남태욱 한국생물공학회 2018 BT NEWS Vol.25 No.2

동학·천도교 사회운동에 관한 사회윤리적 평가와 미래적 과제 : 사회변혁 및 사회통합 이념 모색을 중심으로

남태욱 한국기독교사회윤리학회 2014 기독교사회윤리 Vol.29 No.-

우리사회는 현존하는 다양한 갈등을 해결하고 사회변혁과 통합을 이룰 수 있는 사회이념을 필요로 하고 있다. 필자는 우리 근대사에 주목할 만한 영향을 끼친 동학·천도교의 사회운동에서 나타난 사회이념의 타당성을 논증하여 우리사회의 변혁과 통합이념으로서의 가능성, 한계와 미래적 과제를 인식하는 것을 연구의 목적으로 삼고자 한다. 왜냐하면 동학·천도교의 사회운동은 우리 근대사에서 간과할 수 없는 비중과 위상을 갖고 있기 때문이다. 예컨대, 갑오동학혁명, 3·1독립운동, 신문화운동 등은 우리사회의 근대화에 절대적으로 기여하였음을 역사적으로 결코 폄훼할 수 없다. 필자는 동학·천도교의 창도 목적, 포덕천하(布德天下), 보국안민(輔國安民), 광제창생(廣濟蒼生) 등은 인간과 인간, 개인과 사회, 인간과 자연(생명), 인종과 민족, 문화와 문명을 차별하거나 분리하지 않고 전일적(全一的)으로 통합할 수 있는 대안인 동시에 인류가 추구해야 하고 성취해야 하는 보편적인 이념이라고 생각한다. 필자는 본 연구를 통해서 동학·천도교의 사회변혁 혹은 사회통합 이념이 인류 보편적인 이념임을 논증하고자 한다. 이를 위해 첫째, 동학·천도교 사회운동을 역사적으로 개괄할 것이다. 둘째, 동학·천도교 사회운동을 사회윤리학적 관점으로 평가할 것이다. 셋째, 동학·천도교 사회운동을 추동한 사회이념을 규명 및 한정하고자 한다. 넷째, 동학·천도교 사회이념의 미래적 과제를 제시하고자 한다. I assert that our society requests a social ideology which can resolve so many social conflicts and fulfill social transformation and integration. The purpose of this study prove adequacy of ideology which was found in Donghak·Chondogyo’s social movements. And after that I can be recognize its possibilities and limitations, also I can be find out its future tasks of as an ideology for social change and configuration. Because Donghak·Chondogyo’s social movements were given much weight absolutely in our modern time. So we can’t deny the fact that the Donghak revolution and samil independence movement, new cultural movement etc. were contributed to modernize our society totally. I insist on that Donghak·Chondogyo’s religious objectives that is, podeokcheonha(布德天下), boguganmin(輔國安民), gwangjechangsaeng(廣濟蒼生) etc. can be an alternative plan that change and unify wholly human being and society, nature and nation, culture and civilization. At the same time it can be a universal ideology that have to seek for social justice. In this research I will prove that Donghak·Chondogyo’s ideology for social change and integration is an universal ideology for just life of human beings. For proving it, first, I will try to generalize Donghak·Chondogyo’s social movement historically. Second, I will evaluate it by the viewpoint of social ethics. Third, I will examine and limit its concept. Fourth, I will suggest the future tasks of Donghak·Chondogyo’s social ideology.

라인홀드 니버와 21세기 -기독교 현실주의의 평가와 과제

남태욱 한국기독교학회 2008 한국기독교신학논총 Vol.55 No.-

The 20th century was remembered as the period of the cold war between the USA and the former USSR since the 2nd World War. After the end of the cold war, world citizens believed that the coming 21st Century will be a great time for both justice and peace. However there were countless terrorisms which happened at every corner of world cities. For example, the collapse of the New York’s World Trade Center on September 11, 2001 by Al-Queda was the most surprising scene in the history of terrorism. That eventually motivated the Bush administration to attack against Afghanistan and Iraq immediately. Although world citizens hoped to establish a genuine peace through Bush’s bold attack against terrorism, but it suddenly drove the people into the realm of fear and hopelessness. Thus people realized that peace is eminent need and yet the evil power overshadows both war and terrorism. Then the total collapse of human beings will be evident in the long run. The primary task of this paper is to examine Reinhold Niebuhr’s concept of the Christian realism, which has been criticized by many sociologists, theological scholars, and social activists. This will be done by evaluating his perspectives of the Christian realism both positively and negatively. Since the American hegemony has been regarded as a threatening power to the world peace, it has been necessary to examine Reinhold Niebuhr’s concept of political realism that greatly influenced in shaping the American policy of international relation with the former USSR during the last 20th Century. As Niebuhr claimed that the world peace should be righteous and balanced between two parties, this paper will explore his idea of the Christian realism in terms of understanding what the Christian attitudes toward the world peace and terrorism should be. Finally this paper will argue that Reinhold Niebuhr’s concept of the Christian realism is still a valuable theory that can be applied to the complicated situation of our world, as we pursue a genuine justice and peace. The 20th century was remembered as the period of the cold war between the USA and the former USSR since the 2nd World War. After the end of the cold war, world citizens believed that the coming 21st Century will be a great time for both justice and peace. However there were countless terrorisms which happened at every corner of world cities. For example, the collapse of the New York’s World Trade Center on September 11, 2001 by Al-Queda was the most surprising scene in the history of terrorism. That eventually motivated the Bush administration to attack against Afghanistan and Iraq immediately. Although world citizens hoped to establish a genuine peace through Bush’s bold attack against terrorism, but it suddenly drove the people into the realm of fear and hopelessness. Thus people realized that peace is eminent need and yet the evil power overshadows both war and terrorism. Then the total collapse of human beings will be evident in the long run. The primary task of this paper is to examine Reinhold Niebuhr’s concept of the Christian realism, which has been criticized by many sociologists, theological scholars, and social activists. This will be done by evaluating his perspectives of the Christian realism both positively and negatively. Since the American hegemony has been regarded as a threatening power to the world peace, it has been necessary to examine Reinhold Niebuhr’s concept of political realism that greatly influenced in shaping the American policy of international relation with the former USSR during the last 20th Century. As Niebuhr claimed that the world peace should be righteous and balanced between two parties, this paper will explore his idea of the Christian realism in terms of understanding what the Christian attitudes toward the world peace and terrorism should be. Finally this paper will argue that Reinhold Niebuhr’s concept of the Christian realism is still a valuable theory that can be applied to the complicated situation of our world, as we pursue a genuine justice and peace.

동학의 시천주의 인간론과 라인홀드 니버의 인간이해

남태욱 동학학회 2008 동학학보 Vol.12 No.1

본 연구의 목적은 동학의 시천주의 인간론과 라인홀드 니버의 인간 이해를 통해 한국사회의 사회윤리의 새로운 가능성을 모색하고자 함이다. 구체적으로 첫째, 동학과 라인홀드 니버의 인간 본성을 상호 비교하고자 한다. 둘째, 양자의 인간론의 윤리적, 정치적 의미를 밝히고자 한다. 셋째, 양자의 현대적 의의를 밝히고자 한다. 양자의 인간론은 한편, 19세기 구한말 서세동점, 내우외환의 절체절명의 상황과 20세기 산업화와 대공황과 같은 경제적 위기와 1, 2차 세계대전, 냉전과 같은 정치적 상황 속에서 제기되었다는 것과 각각 조선사회와 미국사회의 사회운동으로 전개되었다는 공통점이 있다. 다른 한편, 인본주의와 기독교 현실주의라는 이론적, 종교적 토대를 달리한다. 그리고 그 실현방법에 있어서도 개인의 수양을 통한 변화와 사회정의를 통해 사회구조의 변혁이라는 차별성이 있다. 양자의 인간 이해와 윤리적 대화는 오늘 우리 사회의 도덕적, 윤리적 위기를 극복할 수 있는 가능성을 열어갈 수 있다고 생각한다. The purpose of this paper is to seek a new socio-ethical paradigm of the Korean society according to the concept of human nature asserted by both the Donghak leader Choi Jae-woo and the American theologian Reinhold Niebuhr. Choi Jae-woo was the founder and leader of the Dong-hak Movement during the late 19th Century in Korea. On the other hand, Reinhod Niebuhr was an American theologian who asserted the necessity of the Christian community's socio-political action during the early 20th Century in the US. As they strongly claimed the necessity of socio- politico-ethical movement regardless of their religious and cultural background, this paper discusses their convergence and divergence on the concept of human nature in terms of their own particular socio-politico-ethical and geographical situation. Accor- dingly, this paper will be divided as three chapters: (1) the comparative analysis of the concept of human nature between the Dong-hak leader Choi Jae-woo and the American theologian Reinhold Niebuhr; (2) their understanding of human nature claimed within their own socio-politico-ethical situation; (3) their practical appli- cation to the contemporary society. In conclusion, this paper therefore suggests that their concept of human nature asserted within their own particular socio-political context may provide some alternative ideas for the building of a more improved Korean social system and structure in the 21st Century.

동학농민혁명과 독일농민전쟁의 비교적 고찰 : F. 엥겔스의 외피론을 중심으로

남태욱 동학학회 2010 동학학보 Vol.19 No.-

The purpose of this study is to examine the relationship between religious Spirituality and social transformation in relation to the commonly associated with two wars such as Donghak Peasant Revolution(1894) and the German Peasants' War(1525). The German War led by the left-wing leader of the Reformation, Thomas Müntzer(1488/9?-1525) will be examined in relation to Donghak's characteristics of radical passion for social change. Especially it will be analyzed the coherence or unity found out at the both Wars' religious experience or teaching in terms of social transformation movement. In order to do this, it will be criticized Friedrich Engels(1820-1895)' theory of religious outer skin. This is because his theory provides some hermeneutical tools to explicate both Wars. At this point, it will be also analyzed the genuine cause and its historical significance of both Wars. Therefore, this paper reflects on the social status of Cheondogyo in Korean society that succeeded the legacy of Donghak and the spirit of its Peasant Revolution. Moreover, it will be indicated that the current statute of Cheondogyo is less than Donghak of the late 19th Century. In particular, this paper proposes that the future of Chondogyo must develop her legacy of Donghak to be the leading of social transformation in the 21st Century. 본 연구의 목적은 동학이 주도했던 갑오농민혁명(1894)과 종교개혁 좌파 지도자인 토마스 뮌처(Thomas Müntzer, 1488/9?-1525)가 이끈 독일농민전쟁(1525), 두 전쟁에 공통적으로 관련된 종교적 영성과 사회개혁(변혁)과의 관계를 밝히는 것이다. 구체적으로 종교적 체험과 가르침, 그리고 사회변혁과의 연속성(일관성)과 통일성을 밝히고자 한다. 이를 논증하기 위해 두 전쟁에 공통적으로 적용되고 있는 한 해석학적 관점인 F. 엥겔스(Friedrich Engels, 1820-1895)의 종교적 외피론에 대한 심층적인 이해와 비판, 그리고 뮌처 자신이 전 생애를 통해 추구한 혁명적 신앙을 규명함으로써, 독일농민전쟁과 동학농민혁명에 대한 진정한 원인과 역사적 의의를 밝히고자 한다. 마지막으로 동학농민혁명의 유산을 계승한 천도교의 오늘날 위상을 비판적으로 반성하고 과거와 같은 혁명적 역량을 발전시키기 위한 미래적 과제에 대하여 고민하고자 한다.

Chemically Exfoliated Tungsten Disulfide (WS₂) Nanosheets with Metallic 1T’ Phase Transformed by Antioxidant trigger

남태욱,오진영,김준수,정민우,( Dinda Bazliah ),( Vo Ngoc Thanh Phuong ),이현빈,조창희,이소림,( Dang Xuan Nghia ),( Huynh Kim Anh ),이혜주,조현이,김민정 ( Minjeong Kim ) 한국공업화학회 2022 한국공업화학회 연구논문 초록집 Vol.2022 No.-

동학의 시천주의 인간론과 라인홀드 니버의 인간 이해 : 인간 본성과 윤리ㆍ정치적 의미를 중심으로

남태욱 동학학회 2008 동학학보 Vol.15 No.-

원자층 박막 증착법을 이용한 나노 소자 공정 및 물성 연구

남태욱,김형준,Nam, Tae-Uk,Kim, Hyeong-Jun 한국정보디스플레이학회 2013 인포메이션 디스플레이 Vol.14 No.5