혈중 알코올 농도와 호흡기 알코올 농도 상관성: 한국인 남성

이승환,남범우,서정석,Yi, SeungHwan,Nam, BeomWoo,Seo, JeongSeok 한국자동차안전학회 2015 자동차안전학회지 Vol.7 No.4

The relationship between BAC(Blood Alcohol Concentrations) and BrACs(Breath Alcohol Concentrations) and also partition ratio of healthy Korean adult males (96 males) are researched in this paper and its dependency is described according to TBW (total body water), BMI (body mass index), BFM (body fat mass), and PBF (percentage of body fat). Among the above four variables, TBW affects significantly to the partition ratio compared to the other variables. The partition ratio of Korean healthy males showed 1,913 (95 % Confidence Interval (C.I.) from 1,889 to 1,937) for the whole time intervals. However, when Q was averaged after 60 minutes later, its values was 2,011 (95 % C.I. from 1,982 to 2,040). Bland-Altman plots showed the compatibility of measurement methods of multi-gas analyzer, and the biases according to the partition ratios (Q=2,100 and Q=1,913) gave -0.0052 % (95 % CI from -0.0059 to -0.0045%) and -0.0004 % (95 % CI from -0.0011 to +0.0003%), respectively.

단순 코골이 또는 폐쇄성 수면 무호흡증이 있는 후기 남자 청소년에서 다면적 인성 검사 결과

유민지 ( Minji Yu ),남범우 ( Beomwoo Nam ),서정석 ( Seo Jeong Seok ),노수림 ( Soo Rim Noh ),이종국 ( Jonggook Lee ),이제정 ( Je Jung Lee ),서희영 ( Heeyoung Seo ),김태현 ( Taehyun Kim ),오근 ( Keun Oh ) 한국정신병리진단분류학회 2021 精神病理學 Vol.25 No.2

Objectives The purpose of this study was to quantitatively assess the degree of Simple Snoring(SS) or Obstructive Sleep Apnea (OSA) affecting mental health through the results of multiphasic military personality inventory. Method We collected and analyzed the results of the military personality inventory(MPI) for healthy controls and SS or OSA patients among the 19-year-old men who visited the Military Manpower Administration from January 2008 to January 2013. MPI invented for Korean military test has similar system to Minnesota multiphasic personality inventory. Results Among demographic data, education level was lower in SS or OSA group (χ2=69.49, p<0.001). Socio-economic status and parents-relationship were not statistically different between two groups (χ2=2.94, p=0.401; χ2=2.01, p=0.570). BMI was higher in SS or OSA group (t=-8.24, p<0.001). Among validity scale, the score of faking good subscale was lower in SS or OSA group (t=3.157, p=0.002). Each score of faking bad and infrequency subscale was higher in SS or OSA group (t=-3.741, p<0.001; t=-2.766, p=0.006). Among neurosis scale, each score of anxiety, depression, somatization and personality disorder subscale was higher in SS or OSA group, respectively (t=-4.060, p<0.001; t=-3.977, p<0.001; t=-4.293, p<0.001; t=-3.499, p=0.001). Among psychopath scale, each score of schizophrenia and paranoia subscales were not statistically different between two groups (t=-1.669, p=0.096; t=-2.012, p=0.045). Conclusion According to MPI results, we can confirm that SS or OSA patients may appear feature such as anxiety, depression, somatization and personality tendency (introversion or impulsivity) than the control group.

군신체검사 대상자 중 기면증이 있는 남성의 성격 특성

이한준 ( Hanjun Lee ),남범우 ( Beomwoo Nam ),서정석 ( Jeong Seok Seo ),김태 ( Tae Kim ),노수림 ( Soo Rim Noh ),이제정 ( Je Jung Lee ),오근 ( Keun Oh ),서희영 ( Hee Young Seo ),김태 ( Tae Kim ),이종국 ( Jonggook Lee ) 한국정신병리진단분류학회 2021 精神病理學 Vol.25 No.2

Objectives The purpose of this study was to quantitatively assess multiphasic personality inventory results of narcolepsy affecting mental health using military personality inventory in Korea. Method We registered the 19-year-old men who visited the Military Manpower Administration from February 2010 to January 2013. Results Among demographic characteristics, both narcolepsy and control groups are 19-year-old male. Education level and socioeconomic status are higher(χ2=4.23, p=0.04 ; χ2=17.94, p=0.001) in control group. BMI is higher(t=-3.10, p=0.002) in narcolepsy group. Parents relationship showed no difference between control and narcolepsy groups(χ2=7.57, p=0.06). Among validity scales, score of faking good subscale was higher(t=4.368, p<0.001) in control group, of faking bad subscale was higher(t=-2.497, p=0.013) in narcolepsy group, of infrequency subscale showed no difference(t=-0.466, p=0.642) between control and narcolepsy groups. Among neurosis scales, the score of somatization, depression, anxiety, and personality disorder subscales were higher in narcolepsy group, respectively(t=-4.721, p<0.001 ; t=-5.189, p<0.001 ; t=-6.068, p<0.001 ; t=-2.161, p=0.032). Among psychopath scales, the score of paranoia subscale was higher in narcolepsy group(t=-2.795, p=0.006), of schizophrenia subscale showed no difference (t=-0.687, p=0.493). Conclusion According to MPI results, we suggest that narcolepsy patients are more concerned with their somatic symptoms, more depressive and anxious, have more introverted or impulsive tendency and paranoid traits.

부모의 양육 행동이 중학생의 자아탄력성에 미치는 영향

안민철,서정석,문석우,김태호,남범우,Ahn, Min Choul,Seo, Jeong Seok,Moon, Seok Woo,Kim, Tae Ho,Nam, Beomwoo 한국정신신체의학회 2016 정신신체의학 Vol.24 No.2

연구목적 중학생의 성격 발달 및 자아탄력성은 부모의 양육행동과 깊은 관계가 있다. 중학생의 자아탄력성과 부모의 양육행동과의 관계와 이에 대한 요인을 알아보고자 한다. 방 법 한국 아동청소년 패널조사 2013년 자료를 활용하여 층화 다단계 집락 포집 방법으로 표본(남성: 1,075; 여성: 1,033)을 선정하였으며 부모 양육행동 척도와 자아탄력성 척도를 사용하여 부모 양육행동과 중학생의 자아탄력성을 평가하였다. 중학생의 자아탄력성에 영향을 주는 부모 양육행동을 알아보기 위해 선형 회귀분석을 시행하였으며 영향 요인과의 상관성을 알아보기 위하여 피어슨 상관분석을 시행하였다. 결 과 회귀 분석 결과 부모의 양육행동 중에 합리적 설명, 애정, 관심, 비일관성이 자아탄력성에 영향을 주는 것으로 나타났다. 상관 분석 결과 부모의 양육행동 중에 합리적 설명, 애정, 관심이 자아탄력성과 유의한 양의 상관관계를 보였다(r=0.24, r=0.31, r=0.22, p<0.01). 그러나 중학생의 자아탄력성과 비일관성은 유의한 음의 상관관계를 보이지 않았다. 결 론 부모의 양육행동에서 합리적 설명, 애정, 관심이 높을수록 자아탄력성이 높아짐을 의미한다. 또한 비일관성이 중학생의 자아탄력성에 영향을 주는 요인이나 유의한 상관성을 보이지 않은 것을 통해 유아와는 달리 중학생의 자아탄력성은 다른 요인들에 의해 영향을 받을 가능성을 시사한다. 이 연구는 중학생의 정신과적 문제에 대한 정신사회적 접근에 도움이 될 것이다. Objectives : Parental behavior is related to personality development and ego resilience in the childhood. The objective of this study was to identify the influence of parental behavior on ego resilience in Korean middle school student. Methods : Subjects were selected based on stratified multi-stage cluster sampling in Korea youth panel study 2013(Boy : N=1,075, Girl : N=1,033). We used Parental behavior inventory(PBI) to estimate parental behavior and the Ego resilience scale to estimate ego resilience. The data were statistically analyzed using a Pearson correlation analysis and regression analysis with the statistical package for the social sciences(SPSS). We considered differences to be significant when p<0.05. Results : A regression analysis showed that rational explanation, affection, Interest and inconsistency of the parental behavior domains influence ego resilience. Also rational explanation, affection and Interest of the parental behavior domains showed a significant positive correlation with ego resilience(r=0.24, r=0.31, r=0.22, p<0.01). In contrast to early childhood studies, inconsistency showed no significant correlation. Conclusions : Adolescents who had taken more rational explanation, interest and affection from their parents were more likely to have higher ego resilience. However, inconsistency of parental behavior showed no correlation with ego resilience of adolescents, which means that they are affected by several other factors than parental behavior. This study would be a basic research that could be a help to psychosocial approach in pediatric psychiatry.

한국 성인 여성의 혈중 알코올 농도와 알코올의 약동학적 특징 및 영향 요인

유전원(Jeonwon Yu),이보람(Boram Lee),안민철(Minchoul Ahn),남범우(Beomwoo Nam),이상호(Sangho Lee),이승환(SeungHwan Yi),서정석(Jeong Seok Seo) 한국중독정신의학회 2015 중독정신의학 Vol.19 No.2

Background and Objectives : The aim of this study was to evaluate alcohol pharmacokinetics, such as blood alcohol concentration and alcohol elimination rate, and to identify the cor-relations between various alcohol metabolism factors in healthy Korean female adults. Materials and Methods : Ninety-one subjects were randomly divided into two groups. One group was provided as much as 0.35 mg/mL/kg of alcohol and the other as much as 0.70 mg/mL/kg, and blood alcohol concentration was measured 15, 30, 45, 60, 90, 120, 180, and 240 min af-ter the women finished drinking. Results : The subjects’ mean alcohol elimination rate (β) was -0.002379 mg/100 mL·h, and there was no statistically significant difference in elimination rate between the two groups. The mean time to reach maxi-mum blood alcohol concentration was 45 minutes, alcohol ab-sorption rate was 0.1123±0.1799 g/L/min, and the area under the concentration curve was 109.15±62.95. Among the factors that correlated with alcohol metabolism, alcohol absorption rate and follicle-stimulating hormone were statistically significant, but age, body mass index, and body fat percentage were not significantly correlated with alcohol metabolism. Conclusion : These results suggest that the β values for healthy Korean females can differ from the cut-offs that are currently used in Korea, which suggests that the legal limit for driving under intoxication should be adjusted.

한국인 알코올사용장애 임상경과 및 생물정신사회적 요인 규명을 위한 임상 및지역기관 전향적 연구 : ( I ) CRF 개발과정 및 단면적 조사결과

김홍진(Hong Jin Kim),이수비(Soo Bi Lee),정원미(Won Mi Jung),서정석(Jeong Seok Seo),남범우(Beomwoo Nam),조근호(Keun Ho Joe),이해국(Hae Kook Lee),정슬기(Sulki Chung),기선완(Seon Wan Ki)박일호(Il Ho Park) 한국중독정신의학회 2018 중독정신의학 Vol.22 No.1

Objectives : The purpose of this study was to develop a standard case record form (CRF) and to identify the specific biopsychosocial factors influencing a clinical course of patients with alcohol use disorder in Korea. Methods : The CRF was developed with reference to the six-domain assessment of the American Society of Addiction Medicine, taking account of the need for a multifaceted evaluation of alcohol use disorders. We divided Korea into six regions, and the subjects who registered in the first year will be on surveillance for the next three years. Results : We present epidemiological and clinical data from the CRF completed from March to June 2016. In the CRF registration survey, the total number of eligible patients was 247 in the Medical centers, and 193 in community centers for mental health and addiction. Conclusion : The CRF developed for this surveillance can assess a six-domain model, with information taken from patient’s drinking history to social support and quality of life. To my knowledge, this is the first nationwide survey of AUD patients in Korea as conducted by a naturalistic and prospective framework. These results could be an important basic data to determine the appropriate service and treatment level for AUD pat