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잠복정소(潛伏精巢)흰쥐에 있어서 정소(精巢)FSH 및 LH 수용체(受容體)의 수준변화(水準變化)에 관한 연구
김형태,정영채,김창근,Kim, H.T.,Chung, Y.C.,Kim, C.K. 대한생식의학회 1984 Clinical and Experimental Reproductive Medicine Vol.11 No.2
The purpose of this experiment was to investigate the effects of experimental cryptorchidism on the levels of testicular FSH, LH receptor. One hundred and thirty two male rats weighing 100${\pm}$10g, 45 days old, were divided into three groups of control, bilateral cryptorchidism and unilateral cryptorchidism which was subdivided into two groups of scrotal testis and abdominal testis. Thirty to forty two heads of rats were allotted to each group. Five to eight rats from each group were randomely sacrificed at 1, 2, 3, 4 and 5 weeks after surgical induction of cryptorchidism. Testis was removed for assay of FSH, LH receptors. The results obtained were as follows. 1. The levels of FSH receptors per 10mg testicular tissue in abdominal testis of unilateral cryptorchid group and bilateral cryptorchid group tended to decrease gradually toward 5th week and these levels at 2nd, 3rd, 4th and 5th week were significantly lower than those levels of control group and scrotal testis of unilateral cryptorchid group. On the other hand; the ranges of affinities of FSH receptors of abdominal testis in unilateral and bilateral cryptorchid group were 2.2 - 6.67 ${\times}10^{11}M^{-1}$ and 3.6 - 4.8 ${\times}10^{11}M^{-1}$ respectively, and these values were slightly higher than those of control group (1.43 - 3.98 ${\times}10^{11}M^{-1}$) or those of scrotal testis in unilateral cryptorchid group (1.41 - 3.25 ${\times}10^{11}M^{-1}$). Especially at I and 4 weeks after treatment the affinities of abdominal testis in unilateral and bilateral cryptorchid group were significantly higher than those of other group (P <0.01). 2. The levels of LH receptors in 10mg testicular tissue tended to increase with elapse of time in control and in scrotal testis of unilateral cryptorchid group. But the levels of LH receptors of abdominal testis in unilateral and bilateral cryptorchid group tended to decrease after treatment and were significantly lower than control group at 1 (P <0.01),2,4 and 5 weeks after treatment (P < 0.05). The affinities of LH receptors were not significantly different among treatments except those of bilateral cryptorchid group and abdominal testis of unilateral cryptorchid group being significantly higher than that of the control at 4 weeks after treatment.
김형태(H. T. Kim),김정중(J. J. Kim) 한국전산유체공학회 1997 한국전산유체공학회지 Vol.2 No.1
A FA-FD hybrid method, developed for solving three-dimensional incompressible Navier-Stokes equations, is applied to calculate three-dimensional laminar flows through a square duct with a 90˚ bend. The method discretizes the convective terms in the primaryflow direction with 3rd-order upwind finite-differences and the convective and diffusive terms in the transverse directions with the two-dimensional finite analytic method. The non-staggered grid system is used and the pressure-velocity coupling is achieved by a global iteration procedure based on the PISO algorithm. Detailed comparisons between the computed solutions and the available experimental data are given mainly for the velocity distributions at cross-sections in a 90˚ bend of a square duct with both fully developed and developing entry flows. Although the computational result shows generally a good agreement with the experimental data, there are some significant discrepancies underlining the necessity of more accurate numerical methods as well as reliable experimental data for their validation.