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화병환자의 불면증상에 대한 침치료 유효성 평가연구: 환자-평가자 눈가림, 무작위배정, 일반대조군 임상시험
이고은 ( Go Eun Lee ),김남권 ( Nam Kwon Kim ),김향이 ( Hang Yi Kim ),강형원 ( Hyung Won Kang ) 대한한방신경정신과학회 2012 동의신경정신과학회지 Vol.23 No.1
Objectives: The purpose of this research is to examine the effects of acupuncture treatment on Hwa-byung patient`s insomnia. Methods: The study was performed through a patient-assessor blind, randomized, placebo-controlled trial in which the volunteers, data collectors and analysts were unaware of individuals who were receiving the treatment. A total of thirty-seven volunteers were divided into 2 groups. 18 subjects were placed into a trial group and 19 subjects into a control group by a randomization table. The trial group was treated on bilateral Shigu, Ahnmyun, B62 (Shinmaek), and K6 (Chohae), while the control group was not given any other treatment. The ISI(Insomnia Severity Scale) was measured as the 1st evaluative instrument, and then a comparative analysis was conducted by comparing the results with those measured by a Likert scale for major symptoms of Hwa-byung, PSQI, Hwa-byung scale, BDI, STAI, and STAXI. Results: In the ISI, PSQI, and the Likert scale regarding major symptoms of Hwa-byung, Hwa-byung scale, BDI, and STAI, more significant decreases were found in those concerning the trial group compared to those of the control group from a statistical perspective. However, in the STAXI, regarding the trial group, there was no significant decrease compared to the control group. Conclusions: The results suggest that acupuncture treatment is effective in the treatment regarding Hwa-byung patients who suffer from insomnia.
한의학 칠정(七情)에 기반을 둔 핵심감정평가척도 개발을 위한 예비 연구
이고은 ( Go Eun Lee ),박보영 ( Bo Young Park ),김향이 ( Hang Yi Kim ),유영수 ( Yeoung Su Lyu ),강형원 ( Hyung Won Kang ) 대한한방신경정신과학회 2014 동의신경정신과학회지 Vol.25 No.1
Objectives: The aim of this study is to investigate the core emotion assessment instrument based on the Chiljeong. Methods: We searched for a literature review of oriental medicine and established the operational definition. Based on the existing psychological scale measurement, we selected the items and analyzed the reliability through a two-step preliminary study. Results: 1) Through the analysis of reliability after the two-step preliminary study (first: 170 items, n=63, second: 152 items, n=42), we had excellent internal consistency (Cronbach``s alpha > 0.70) as well as good test-retest reliability (>0.70). Thus, we demonstrated that this scale had reliability. 2) Analyzing the correlation of each emotion, we had a comparatively strong positive-correlation (>0.6), except for Hui, and found a particularly high correlation of Sa, U and Bi. Conclusions: We developed the final 141 items of the core emotion assessment instrument through the two-time preliminary study. In the future, the main study on the clinical and non clinical groups of various ages should be continued.
단순정맥압박검사에 의한 혈액내 FDP ( fibrinogen degradation produc ) 농도 변화를 이용한 인슐린비의존성 당뇨병환자와 뇌졸중환자의 대혈관기능 이상 진단
김상훈(Sang Hoon Kim),심성춘(Sung Chun Sim),장남수(Nam Soo Jang),박창영(Chang Young Park),최윤상(Young Sang Choi),이규백(Kyu Beck Lee),강진호(Jin Ho Kang),김향(Hang Kim),조윤경(Yoon Kyung Cho),김유리(Yoo Lee Kim),이상종(Sang Jong Le 대한내과학회 1999 대한내과학회지 Vol.56 No.5
N/A Objectives : In diabetic patients, the incidence of atherosclerotic disease are increased, which may be due to decreased fibrinolytic activity. The aim of study is to elucidate the relationship between angiopathies and vascular function evaluated by simplified venous occlusion test in patients with non-insulin dependent diabetes mellitus (NIDDM) and cerebrovascular accident (CVA). Methods : The study was conducted on 63 patients who were hospitalized during the period from March 1, 1994 to May 30, 1997. The serum concentration of fibrinogen degradation products (FDP) was measured before and 5 min after venous occlusion in 31 NIDDM patients, 16 CVA patients and 16 age-matched control subjects. FDP was measured with the anti-fibrinogen- coated latex particle agglutinin assay system. Results : 1) The basal serum FDP level was higher in diabetic patients with macroangiopathy (12.3±5.8 ug/ml) and patients with CVA (11.2±5.1 ug/ml) than in control subjects (5.7±1.8 ug/ml) (p<0.05). 2) The increment of serum FDP level after venous occlusion in diabetic patients with microangiopathy (6.6±2.2 to 10.3±4.1 ug/ml) and control subjects (5.7±1.8 to 11.4±4.3 ug/ml) was significantly higher than basal serum FDP level (p<0.05). But the increment of serum FDP level after venous occlusion in diabetic patients with macroangiopathy (12.3±5.8 to 15.2±5.1 ug/ml) and patients with CVA (11.2±5.1 to 13.7±4.8 ug/ml) wasn't significantly higher than basal serum FDP level. 3) The increment rate of serum FDP after venous occlusion in diabetic patients with macroangiopathy (24.4±29.3%) and patients with CVA (29.4±34.5%) was significantly lower than diabetic patients with microangiopathy (66.3±71.7%) and control subjects (84.1±69.3%) (p<0.05). Conclusion : The responsiveness of fibrinolytic activity to venous occlusion was significantly lower in diabetic patients with macroangiopathy, as in patients with CVA, compared with that in control subjects. We conclude that measurement of the increase in serum FDP concentration 5 min after venous occlusion may be useful to detect vascular dysfunction in patients with macrovascular disease caused by atherosclerosis.