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흰쥐에서 이부프로펜 리신염의 물리화학적 특성 및 약물동태에 관한 평가
신대환(Dae Hwan Shin),김시현(Si Hyun Kim),박승혁(Seong Hyeok Park),김태성(Tai Sung Kim),한건(Kun Han),정연복(Youn Bok Chung),조한준(Han Jun Jo) 大韓藥學會 2011 약학회지 Vol.55 No.3
Two types of water soluble lysine salts of ibuprofen were prepared and evaluated. Physicochemical properties for ibuprofen-l-lysinate (IBL-l), ibuprofen-dl-lysinate (IBL-dl) and ibuprofen (IB) were studied on melting point, specific ratation, UV spectra and 1H-NMR spectra. There were not differences between IBL-dl and IBL-l in UV spectra and 1H-NMR spectra. The pharmacokinetic parameters of IB were compared to those of its lysine salts (IBL-l and IBL-dl) after i.v. or oral administration at the dose of 50 mg/kg (calculated as IB). Total body clearance (CLt) and area under the plasma concentration-time curve (AUC) were not different between IB group and IBL groups after i.v. administration. On the other hand, IBL-l and IBL-dl produced peak plasma concentrations (Cmax) significantly ealier and higher than IB. Time to reach peak concentration (Tmax) after IBL administration was lower than that after IB administration. There was no difference in AUC across all different groups (IB, IBL-l and IBL-dl) after oral administration. However, absorption rate constant (ka) of IBL-l and IBL-dl were significantly increased than that of IB. These results indicated that the administration of IBL-l and IBL-dl may be advantageous if rapid and reliable onset of pain relief is required.
김태성,주은경 충북대학교 과학교육연구소 1995 과학교육연구논총 Vol.11 No.1
The purpose of this paper is to examine the effect of learning by developing and applying CAI prpgram in the secondary school mathematics education. As a result of study, we can find the facts as follow ; 1. The group taught by using CAI program scored higher academic achievement than those taught by conventional method of instruction 2. Comparing the academic achievement of the experimental group between before experiment and after it, the instruction using CAI program improved in learners' academic achievement. Therefore, we can know that the instruction using CAI program is more effective than conventional method in improving learners' academic achievement.
Measurability 와 Bourgain 성질에 관하여
김태성,윤주한 충북대학교 과학교육연구소 1991 과학교육연구논총 Vol.8 No.1
본 논문에서는 Bourgain 성질과 B^*-성질을 소개하고, Ψ가 Bourgain 성질에 가질때, Ψ에 있는 각원소는 가산개의 값을 갖는 함수들에 의하여 a.e. 평등하게 근사시킬 수 있음을 보였고, Ψ가 L_1의 부분집합이고, ralatively weakly compact이고 B^*-성질을 가지면, Ψ는 ralatively compact 임을 보였다.
김태성 충북대학교 과학교육연구소 1995 과학교육연구논총 Vol.11 No.1
In order to reach the desirable education in 21-st century, mathematics education will go toward the following three direction: 1. Mathematics curriculum should be composed to extend the linguistic functions of mathematics. 2. Mathematics should be taught that students will understand the beauty of mathematics 3. Mathematics education should be developed that students will find the creativity of mathematics
왜망초(Erigeron sumatrensis Retz)群落에 있어 생산구조의 季節的 變化에 관한 생태학적 硏究
金泰成 건국대학교 1988 論文集 Vol.26 No.1
The purpose of this experiment is to investigate the seasonal change and productivity of the horse-weed(Erigeron sumatrensis) plant community. The results are as follows 1, According to the germination season, the horse-weed, when germinated in autumn, became a winter annual of Rosette and, when germinated in spring, it became an annual of erect forms. 2. The relative growth rate of the plant community was 0.024(g/g/day) in the early period, but it was 0.039(g/g/day) from the middle of July because the plant community grew rapidly. 3. As the plant community grew, the density changed from 285/m2 in the early period to 175/m2~ 185/m2 in August. 4. Change of productive structure was similar to that of the Garmineae in which the leaves were distributed in the middle part of the plant community. 5. The light transmission rate of the plant community was smaller than that of the Gramineae, and LAI was 6.8 which was comparatively large. As mentioned above, it can be said that the plant community of horse-weed has a high transmission rate in its size, shape, arrangement and so on, and it also has a superior characteristic in community photosynthesis by making the productive structure of the Gramineae in which the leaves are distributed in the middle part of the plant community.
酒精粕混合 糞尿殘渣의 腐熟에 따른 燐酸有效化에 關한 硏究
金泰成 건국대학교 1986 論文集 Vol.23 No.1
This experiment was conducted to study decomposing effect of the contents of W-P2O5, C- P2O5 on fermentation hull mixing night soil sludge, which was the highest phosphate content among the other industrial wastes. The results obtained are summerized as follows: 1) The change of PH showed the highest increase at ten days of stacking regardless of the treatment, the pH was increased with increase of the mixing ratio of fermentation hull. 2) Night soil cake treatment was not showed difference in C- P2O5, W- P2O5 availability during composting period. On the contrary, the concentration of various phosphate was slightly increased by fermentation hull mixing treatment. 3) The highly negative correlation was showed between C/N ratio and C- P2O5 concentration at fermentation hull mixing treatment.