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도서성(Insularity)과 전통성에 바탕을 둔 이상적인 도서지역 주거모델 개발에 관한 연구
김지민,Kim Ji-Min 한국주거학회 2005 한국주거학회 논문집 Vol.16 No.5
This paper is architectural paper which has been studied about residential culture of Southwestern Island from 18C to now. It's main object is suggest a new residential type. Contents of research is 1, to survey a history and a cultural environment of island. 2. to survey and rearrange residence(traditional, modem) which has been built from the past to the present, and establish a history of residence and a theory. 3. to search for architectural space, shape(form), and architectural community, etc. which can be continued. 4. to suggests ideal future residence type of islands. Effectiveness of Research is 1. This study suggests a new theory and a new method to the field of residential science, especially to the residence of island area. 2. In this study, traditional theory of residence be reflected in the modern architectural design.
김지민,백경원,신홍범,김수인,연규월,임원정,Kim, Ji-Min,Paik, Kyoung-Won,Shin, Hong-Beom,Kim, Soo-In,Yun, Kyu-Wol,Lim, Weon-Jeong 대한수면의학회 2005 수면·정신생리 Vol.12 No.2
Zolpidem은 벤조디아제핀 수용체에 선택적으로 작용하는 약물로 장기 투여 시에도 내성과 금단증상이 적은 장점이 있다. 최근 국외문헌에서 zolpidem 복용후 나타난 야간 식이 장애 사례들이 보고되면서 zolpidem 투약 시 역으로 나타나는 수면장애 호소에 관심이 늘어나고 있다. 저자들은 야간식이 증후군이나 수면장애 기왕력이 없으나 불면을 호소하는 정신과 환자들이 다양한 기간(2주에서 15개월) 동안 zolpidem을 투약한 후, 갑자기 부분적 혹은 전체적 기억상실을 동반한 야간 식이 충동 및 행동을 보였고 zolpidem 투약을 중단하거나 감량하자 하루 만에 증상이 사라진 6사례를 경험하였기에 보고하였다. Objective: The authors would like to find the relationship between zolpidem and nocturnal eating episodes in diverse psychiatric patients. Method: We evaluated case series of 6 patients who showed nocturnal eating episodes after takine zolpidem. Results: We have experienced 6 cases who showed nocturnal eating behavior after taking zolpidem. They included 3 patients with schizoprenia, a patient with major depressive disorder, a patient with PTSD and a patient with bipolra I disorder. With reducing or discontiuation of zolpidem, their nocturanl eating resolved. Conclusion: This finding strongly suggests the relationship between zolpidem and the nocturnal eating episode. Physicians should be aware that zolpidem might induce nocturnal eating behaviors.
김지민,신성찬,권현근,천용일,노정훈,이병주,Kim, Ji Min,Shin, Sung-Chan,Kwon, Hyun-Keun,Cheon, Yong-Il,Ro, Jung Hoon,Lee, Byung-Joo 대한후두음성언어의학회 2021 대한후두음성언어의학회지 Vol.32 No.1
Background and Objectives During speech, the vocal folds oscillate at frequencies ranging from 100-200 Hz with amplitudes of a few millimeters. Mechanical stimulation is an essential factor which affects metabolism of human vocal folds. The effect of mechanical vibration on the cellular response in the human vocal fold fibroblasts cells (hVFFs) was evaluated. Materials and Method We created a culture systemic device capable of generating vibratory stimulations at human phonation frequencies. To establish optimal cell culture condition, cellular proliferation and viability assay was examined. Quantitative real time polymerase chain reaction was used to assess extracellular matrix (ECM) related and growth factors expression on response to changes in vibratory frequency and amplitude. Western blot was used to investigate ECM and inflammation-related transcription factor activation and its related cellular signaling transduction pathway. Results The cell viability was stable with vibratory stimulation within 24 h. A statistically significant increase of ECM genes (collagen type I alpha 1 and collagen type I alpha 2) and growth factor [transforming growth factor β1 (TGF-β1) and fibroblast growth factor 1 (FGF-1)] observe under the experimental conditions. Vibratory stimulation induced transcriptional activation of NF-κB by phosphorylation of p65 subunit through cellular Mitogen-activated protein kinases activation by extracellular signal regulated kinase and p38 mitogen-activated protein kinases (MAPKs) phosphorylation on hVFFs. Conclusion This study confirmed enhancing synthesis of collagen, TGF-β1 and FGF was testified by vibratory stimulation on hVFFs. This mechanism is thought to be due to the activation of NF-κB and MAPKs. Taken together, these results demonstrate that vibratory bioreactor may be a suitable alternative to hVFFs for studying vocal folds cellular response to vibratory vocalization.
19세기 한국 남서해(南西海) 도서지역(島嶼地域) 민가(民家)의 유형적 체계
김지민,Kim, Ji-Min 한국건축역사학회 1992 건축역사연구 Vol.1 No.1
This study is an architectural investigation paper which has been investigated for 5 years from 1986 about commoner's traditional houses and village in southwestern island area of Korea. Man has lived in this area form the prehistoric age. But from 13C to 14C and in 16C most of people had left this islands by external invasion (Japan) and from 17C many people have lived in real earnest. This area did not have cultural interchange easily than inland area because of geographical conditions, Therefore, so far, many traditional factors have been handed down and especially, a good many commoner's traditional houses exist. The time of builging of these houses is mainly 19C and building shape of those days remains nearly as it is. About 450 houses have been investigated for 5 years. The composition of the houses is composed of Anchae (a centeral house), Sarangchae (an attached house of anchae) and Chukganchae (It has rest room and stores barnyard manure). Somtimes, Sarangchae was ommitted according to the circumstance of the house. Generally, the form of arrangement of house is divided into two shapes; One is 'ㅡ'shape which has only Anchae and the other is 'ㄱ' shape which has Anchae and Sarangchae. In the scale of the house, Anchae averages $41m^2$ and Sarangchae averages $27m^2$.