둥근마 에탄올 추출물의 항염증 효과

김정환ㆍ김대용(Jeung Hoan KimㆍDae Yong Kim) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.1

Dioscorea bulbifera has been cultivated in Korea, China and Japan as a food, and also widely used as a traditional medicine for a long time. This study was conducted to determine the anti-inflammatory effect of Dioscorea bulbifera ethanol extracts. The inhibitory effect of Dioscorea bulbifera ethanol extracts were evaluated regarding production or expression of inflammatory mediators in macrophage cells. Dioscorea bulbifera ethanol extracts significantly inhibited the expression of IL-4, IFN-γ and PGE2 and expression of COX-2, iNOS, TNF-α, in LPS-stimulated RAW264.7 cells. In addition, we evaluated the inhibitory effect of Dioscorea bulbifera ethanol extracts on an atopic dermatitis-like mouse model. An atopic dermatitis-like skin lesion was induced by repeated treatment of DNCB on the ear skin of ICR mice. The efficacy of Dioscorea bulbifera ethanol extracts was tested by histophathologic analysis. Histophathologic analysis revealed a reduction in the ear thickness in Dioscorea bulbifera ethanol extracts treated mice. These results show that Dioscorea bulbifera ethanol extracts have an anti-inflammatory effect. Therefore, this research suggests that Dioscorea bulbifera may be a potential agent for ameliorating inflammation.

Single CNN-based ENSO forecast model for all target seasons

김정환,함유근 한국기상학회 2019 한국기상학회 학술대회 논문집 Vol.2019 No.10

사일로시스템에 의한 내화학성 단면복구 몰탈의 기계화 시공

김정환,주동철,김경덕,김재성,Kim, Jeong-Hwan,Ju, Dong-Cheol,Kim, Gyeong-Deok,Kim, Jae-Seong 한국시멘트협회 2005 시멘트 Vol.168 No.-

총채벌레 천적 으뜸애꽃노린재(Orius strigicollis)와 미끌애꽃노린재(Orius laevigatus)의 생물학적 특성 비교

김정환,김황용,변영웅,김용헌,Kim, Jeong-Hwan,Kim, Hwang-Yong,Byoun, Young-Woong,Kim, Yong-Heon 한국응용곤충학회 2008 한국응용곤충학회지 Vol.47 No.4

국내종인 으뜸애꽃노린재와 유럽종인 미끌애꽃노린재의 알, 약충 발육기간과 성충의 산란수, 수명, 포식량 및 포장밀도에서 증가량을 비교하였다. 으뜸애꽃노린재와 미끌애꽃노린재의 $15{\sim}30^{\circ}C$에서 알 부화율은 각각 $46.7{\sim}88.2%$와 $65.0{\sim}89.9%$였고, 알기간은 각각 $3.1{\sim}14.9$일과 $3.1{\sim}13.5$일이었다. 두 종의 약충 발육기간은 각각 $9.4{\sim}42.8$일과 $9.3{\sim}42.0$일이었고, 약충기간 생존율은 각각 $2.4{\sim}96.5%$와 $4.3{\sim}80.6%$였다. 두 종의 산란수는 15, 20, 25, 30, $35^{\circ}C$에서 각각 28.1, 107.9, 123.6, 127.3, 18.1개와 101.8, 218.6, 224.5, 219.5, 15.7개였고, 성충수명은 각각 63.4, 40.1, 22.1, 18.3, 11.0일과 70.6, 66.4, 32.6, 34.5, 7.3일로 으뜸애꽃노린재에 비해 미끌애꽃노린재의 산란수가 많고 성충수명은 길었다. 으뜸애꽃노린재와 미끌애꽃노린재의 온도와 일장에 의한 산란수는 $18^{\circ}C$, 16L:8D에서 각각 105.8개와 109.5개였고, 10L:14D에서 각각 1.0개와 63.0개였다. $25^{\circ}C$, 16L:8D에서 각각 142.4개와 191.5개였고, 10L:14D에서 각각 31.8개와 198.8개로 으뜸애꽃노린재는 $18^{\circ}C$, 10L:14D에서에 거의 모든 개체가 휴면하지만 미끌에꽃노린재는 휴면하지 않는다, 으뜸애꽃노린재와 미끌애꽃노린재의 꽃노랑총채벌레 2령 하루 포식량은 각각 14.3마리와 10.9마리이다. 겨울작형 시설재배 파프리카에서 으뜸애꽃노린재는 5월 중순부터 증가하기 시작하여 7월 상순에는 꽃당 1.8마리로 증가하였다. 미끌애꽃노린재는 3월 중순부터 증가하여 6월 상순에는 꽃당 6.6마리로 증가하는 과밀도 현상을 보였다. With the comparison of native Orius strigicollis (Poppius) to European O. laevigatus (Fieber), we investigated biological characteristics such as developmental period, fecundity, life span, predation ability, and augmentation after release. Experiments were carried out at five temperature condition, $15^{\circ}C\;20^{\circ}C,\;25^{\circ}C\;30^{\circ}C$, and $35^{\circ}C$. In the case of O. strigicollis, egg period was $3.1{\sim}14.9$ days (hatchability: $46.7{\sim}88.2%$), and developmental period of nymphs was $9.4{\sim}42.8$ days (survival rate: $2.4{\sim}96.5%$). Fecundity at each temperature was 28.1, 107.9, 123.6, 127.3, and 18.1, respectively. Life span of adults was 63.4, 40.1, 22.1, 18.3, and 11.0 days, respectively. In the case of O. laevigatus, egg period was $3.1{\sim}13.5$ days (hatchability: $65.0{\sim}89.9%$), and developmental period of nymphs was $9.3{\sim}42.0$ (survival rate: $4.3{\sim}80.6%$) days. Fecundity at each temperature was 101.8, 218.6, 224.5, 219.5, and 15.7. Life span of adults was 70.6, 66.4, 32.6, 34.5, and 7.3 days, respectively. In long-day condition (16L:8D), fecundity of O. strigicollis and O. laevigatus was 105.8 $(18^{\circ}C){\sim}142.4(25^{\circ}C)$ and 109.5 $(18^{\circ}C){\sim}191.5(25^{\circ}C)$, respectively. In short-day condition (10L:14D), fecundity of them was 1.0 $(18^{\circ}C){\sim}31.8(25^{\circ}C)$ and 63.0 $(18^{\circ}C){\sim}198.8(25^{\circ}C)$, respectively. Daily prey consumption of second instar Frankliniella occidentalis was 14.3 and 10.9, respectively. In greenhouse, density of O. strigicollis begins to increase from mid May and peaked about early July (1.8 individual/flower), while that of O. laevigatus begins to increase from mid March and peaked about early June (6.6 individual/flower).

아메리카잎굴파리 (Liriomyza trifolii)의 외부기생봉 굴파리좀벌 (Diglyphus isaea)의 생태적 특성 및 저장 조건 구명

김정환,변영웅,김용헌,김황용,Kim, Jeong-Hwan,Byoun, Young-Woong,Kim, Yong-Heon,Kim, Hwang-Yong 한국응용곤충학회 2007 한국응용곤충학회지 Vol.46 No.1

아메리카잎굴파리 외부기생봉인 굴파리좀벌의 온도별 알, 유충, 번데기 발육기간과 성충의 산란수, 기주체액 흡즙수, 성충수명, 저온 저장력 등을 조사하였다. 굴파리좀벌의 알기간, 유충기간, 번데기 기간은 $25^{\circ}C$에서 각각 1.3일, 4.5일, 6.3일이었다. 성충의 산란수, 기주체액 흡즙수, 성충수명은 $25^{\circ}C$에서 각각 305.3마리, 657.0마리, 25.1일이었다. 아메리카잎굴파리 유충 영기별 굴파리좀벌의 산란선호성과 흡즙선호성을 조사한 결과 각각 90.2%와 82.8%가 3령 유충에 집중되었다. 굴파리좀벌의 저온저장에 따른 50% 생존기간은 꿀물 20%희석 용액을 제공할 경우 $5^{\circ}C,\; 10^{\circ}C,\;15^{\circ}C$에서 각각 180일, 150일, 90일이었다. 굴파리좀벌 저온저장 후 산란수는 저장기간 30일, 70일, 140일에서 각각 190.8개, 104.0개, 89.4개였다. Experiments have been performed to investigate biological characteristics of Diglyphus isaea (Walker), an ectoparasite of Liriomyza trifolii (Burgess). At $25^{\circ}C$, development time of D. isaea was estimated as 1.3 days for eggs, 4.5 days for larvae and 6.3 days for pupae. Adult longevity was 25.1 days, and a female adult could lay 305.3 eggs throughout its lifetime. Number of L. trifolii parasitized or killed by the wasp was 962.2 individuals/adult. Most of all parasitized or killed larvae were identified as third instar. With 20% honeyed water as food source, half of the adults could survive 180 days at $5^{\circ}C$, 150 days at $10^{\circ}C$, and 90 days at $15^{\circ}C$. After storing at $10^{\circ}C$ with absolute honey for 30 days, 70 days and 140 days, a female adult in room temperature laid eggs 190.8 individuals, 104.0 individuals and 89.4 individuals, respectively.

R&D와 규모의 영세성이 산업별 총요소생산성에 미치는 영향

김정환,이동기,이부형,주원,Kim, Jung-Hwan,Lee, Dong-Ki,Lee, Bu-Hyung,Joo, Won 한국벤처창업학회 2007 벤처창업연구 Vol.2 No.4

There were many comprehensive analyses conducted within the existing research activities wherein factors affecting technology progress including investment in R&D vis-${\Box}$-vis their influences act as the determinants of TFP. Note, however, that there were few comprehensive analysis in the industrial research performed regarding the impact of the economy of scale as it affects TFP; most of these research studies dealt with the analysis of the non -parametric Malmquist productivity index or used the stochastic frontier production function models. No comprehensive analysis on the impacts of individual independent variables affecting TFP was performed. Therefore, this study obtained the TFP increase rate of each industry by analyzing the factors of the existing growth accounting equation and comprehensively analyzed the TFP determinants by constructing a comprehensive analysis model considering the investment in R&D and economy of scale (smallness by industry) as the influencers of TFP by industry. First, for the TFP increase rate of the 15 industries as a whole, the annual average increase rate for 1993${\sim}$ 1997 was approximately 3.8% only; during 1999${\sim}$ 2000 following the foreign exchange crisis, however, the annual increase rate rose to approximately 7.8%. By industry, the annual average increase rate of TFP between 1993 and 2000 stood at 11.6%, the highest in the electrical and electronic equipment manufacturing business and IT manufacturing sector. In contrast, a -0.4% increase rate was recorded in the furniture and other product manufacturing sectors. In the case of the service industry, the TFP increase rate was 7.3% in the transportation, warehousing, and communication sectors. This is much higher than the 2.9% posted in the electricity, water, and gas sectors and -3.7% recorded in the wholesale, food, and hotel businesses. The results of the comprehensive analysis conducted on the determinants of TFP showed that the correlations between R&D and TFP in general were positive (+) correlations whose significance has yet to be validated; in the model where the self-employed and unpaid family workers were used as proxy variables indicating the smallness of industry out of the total number of workers, however, significant negative (-) correlations were noted. On the other hand, the estimation factors of variables surrogating the smallness of scale in each industry showed that a consistently high "smallness of scale" in an industry means a decrease in the increase rate of TFP in the same industry.

굴파리좀벌(Diglyphus isaea)을 이용한 시설재배 토마토 작형별 아메리카잎굴파리(Liriomyza trifolii) 밀도억제 효과

김정환,변영웅,이관석,김황용,Kim, Jeong-Hwan,Byoun, Young-Woong,Lee, Gwan-Seok,Kim, Hwang-Yong 한국응용곤충학회 2007 한국응용곤충학회지 Vol.46 No.1

서로 다른 세 가지 시설재배 토마토 포장에서 아메리카잎굴파리의 기생천적인 굴파리좀벌의 인위적방사에 의한 밀도억제 효과를 조사하였다. 봄 작형(3-7월)은 4월 하순부터 아메리카잎굴파리 유충 밀도가 주당 1마리일 때부터 굴파리좀벌을 $m^2$당 0.5-1.7마리씩 6회(총 5.8 마리$/m^2$) 방사한 결과, 조사 시작기인 5월 17일에 비해 조사 종료기인 7월 6일의 아메리카잎굴파리 방제가는 97.6%였다. 방사종인 굴파리좀벌의 점유율은 88.9%로 우점 하였다. 여름 작형(6-10월)은 7월 상순부터 아메리카잎굴파리 유충 밀도가 주당 0.4마리일 때부터 굴파리좀벌을 $m^2$당 0.3-0.4마리씩 5회(총 1.8 마리$/m^2$) 방사한 결과, 천적의 효과가 나타나는 7원 22일부터 11월 3일까지의 아메리카잎굴파리 유충 평균 치사율은 84.4%였다. 그러나 방사종인 굴파리좀벌의 점유율은 13.8%로 매우 낮은 반면, 나머지 86.2%는 외부에서 유입된 자생 잎굴파리 기생봉들이 점유하고 있었으며, 그 가운데 굴파리민좀벌(Chrysocharis penthus)이 58.5%로 가장 많이 발생하였다. 가을 작형(7-12월)은 9월 중순부터 아메리카잎굴파리 유충 밀도가 주당 0.7마리일 때부터 굴파리좀벌을 $m^2$당 0.4-1.3마리씩 4회(총 2.7마리$/m^2$방사한 결과, 조사시작기 인 9월 22일 대배 조사 종료기인 12월 16일의 아메리카잎굴파리 방제가는 85.7%였다. 방사종인 굴파리좀벌의 점유율은 83.4%로 우점 하였다. Biological control of Liriomyza trifolii (Burgess) using Diglyphus isaea (Walker) has been evaluated in tomato greenhouse, for three seasonal culture types: spring type (March-July), summer type (June-October) and autumn type (July-December). For spring type, totally 5.8 $individuals/m^2$ of D. isaea has been released at six times from late April, when the density of L. trifolii was about 1.0 individuals/plant. Corrected mortality of Liriomyza trifolii caused by parasitoids was 97.6% at early July, and the proportion of D. isaea was 88.9% of all parasitoids collected in the greenhouse. In the case of summer type, totally 1.8 $individuals/m^2$ of D. isaea has been released at five times from early July, when the density of 1. trifolii was about 0.4 individuals/plant. Corrected mortality of L. trifolii caused by parasitoids was 84.4% during the whole season, but the proportion of D. isaea was very low (only 13.8%). Immigrating parasitoids such as Chrysocharis penthus were synchronized to control the leafminer in the greenhouse. For autumn type, totally 2.7$individuals/m^2$ of D. isaea has been released at four times from mid September, when the density of L. trifolii was about 0.7 individuals/plant. Corrected mortality of f. trifolii caused by parasitoids was 85.7% at mid December, and the proportion of the D. isaea was 83.4%.

포리에틸렌관과 전자식 이음관에 관한 연구

김정환,Kim, Jeong-Hwan 한국상하수도협회 1997 水道 Vol.24 No.2

Hirtenberger(오스트리아 방위산업체)

김정환,Kim, Jeong-Hwan 한국방위산업진흥회 1988 國防과 技術 Vol.- No.109

PLD를 이용한 강유전체(PZT, PST, PT)/YBCO 박막 구조의 제작과 전기적인 특성에 관한 연구

김정환,이재형,문병무,Kim, Jung-Hwan,Lee, Jae-Hyung,Moon, Byung-Moo 한국전기전자재료학회 1998 전기전자재료학회논문지 Vol.11 No.7

(PZT, PST, PT)/ YBCO structured have been grown on single crystal $LaAlO_3$ using in-situ Nb:YAG pulsed laser deposition technique. The optimum conditions of fabrication for high quality films have been established under various oxygen pressure. TBCO was used as a metallic electrode for polarizing ferroelectric thin fillms. Lattice mismatch of these materials were found to be with in 3%. As a result XRD patterns and rocking curves, (PZT, PST, PT)/ YBCO multiayered thin films on $LaAlO_3$ substrates showed preferred orientation to c-axis. For invastigation on electrical properties of ferroelectric thin films, remanent polaiztion $P_r$ and coercive field $E_c$ were measured for three samples. At each optimum condition, they showed the values of P_r=60 \mu C/cm^2 and E_c=240kV/ cm for PT, 30\mu C/cm^2 and 105kV/cm for PZT, 1.5\mu C/cm^2$ and 15kV/cm for PST. Frequency dependence of dielectric properties of ferroelectric thin fillms was also investigated. As a result, it showed the frequency dependence was relatively small in the range of 10Hz~10kHz.