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RISS 인기검색어
- 검색키워드
- 저자 : 김정태 (검색결과 268 건)
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Amorphous rare earth transition metal(RE-TM) film with a strong perpendicular magnetic anisotropy and exhibiting polar Kerr effect at appropriate composition was made using DC magnetron sputtering system with pure Ar gas. This film was overcoated in situ with a transparent SiNx layer to protect it from the oxidation and to enhance the Kerr magneto-optic effect. The reflectances of the double layered RE-TM film were measured as the function of incident angle for s and p polarized light, repectively. The complex index of refraction of the film was obtained by a conventional iteration method using the measured reflectances. We also measured the complex index of refraction of a slide glass plate, a acryl plate, a gold thin film and a aluminium plate. The measured reflectances of all the samples agree well, within the experimental error. with the calculated values using our the complex indices of refraction.
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한국인 골수증식종양 환자에서 JAK2 V617F와 JAK2 exon 12 유전자 변이
Background : Myeloproliferative neoplasm is a heterogenous group of disease characterized by increased hematopoiesis leading to elevated numbers of non-lymphoid cells and/or platelets in the peripheral blood. An acquired somatic mutation in the JAK2 gene resulting in a valine to phenylalanine substitution at position 617(JAK2 V617F) is frequently found in patients with myeloproliferative neoplasm. In some patients with myeloproliferative neoplasm without JAK2 V617F mutation, JAK2 exon 12 mutation was also reported. This study was designed to analyze the frequency of mutations of JAK2 V617F and JAK2 exon 12 in Korean patients with myeloproliferative neoplasms. Methods : We investigated 108 cases of myeloproliferative neoplasms. Analysis for JAK2 V617F gene mutation were performed by allele-specific PCR method. In patients without JAK2 V617F gene mutation (33 cases), JAK2 exon 12 mutation was analysed by single-pass sequencing. Results : In 108 patients, 56 patients were positive for JAK2 V617F mutation. The proportion of JAK2 V617F mutation in each myelopriliferative neoplasm was the following; 10 in 11 with polychthemia vera, 33 in 62 with essential thrombocythemia, 7 in 15 with primary myelofibrosis, 6 in 20 with myeloproliferative neoplasms, unclassifiable. Thirty-three in 52 patients who do not have JAK2 V617F gene mutation, JAK2 exon 12 gene mutation test was done. None of the 33 patients had JAK2 exon 12 gene mutation. Conclusions : These data provide that the JAK2 V617F gene mutation is a main pathogenic gene in Korean myeloproliferative neoplasms. We could not find any JAK2 exon 12 mutations in the patients without JAK2 V617F gene mutation. Further studies for JAK2 exon 12 and other gene mutations should be done in larger groups of myeloproliferative neoplasms. 만성 골수성 백혈병을 제외한 한국인 골수증식종양환자 108명에서 JAK2 V617F 유전자 변이를 탐색한 결과 56명에서 JAK2 V617F 유전자 변이가 관찰되었다. 20세 이하 환자 7명 중 1명에서 JAK2 V617F 유전자 변이가 양성으로 나타났다. JAK2 V617F 유전자 변이가 음성인 환자 중에서 33명에 대하여 JAK2 exon 12 유전자변이를 검사한 결과 모두 음성임을 확인하였다. 한국인의 골수증식종양환자에서도 JAK2 V617F 유전자 변이가 주요 원인유전자임을 확인하였으나, JAK2 exon 12 유전자변이의 존재는 확인할 수 없었다. JAK2 exon 12 유전자변이는 드문 경우에서만 양성으로 나오는 것으로 보아, 추가적인 연구를 통하여 연관성을 확인할 필요가 있다고 사료된다.
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그동안 國內 生命保險産業은 政府의 政策的인 保護育成과 急速한 經濟成長에 힘입어 高度의 成長을 거듭하여 오는 過程에서 收益性이나 財務構造의 健全性보다는 外形成長中心의 經營戰略을 推進해왔다. 그러나 최근들어서는 生保事業도 金融自律化, 證券化, 國際化라는 汎 世界的 물결과 市場開放 壓力속에 대대적인 經營環境 變化에 直面해 있다. 金融機關의 對外的 開放은 外國 金融機關들이 自國의 制度에 비하여 韓國의 金融制度가 金融機關 經營에 지나친 制約과 統制를 가하고 있다는 불만속에 進行되고 있어 앞으로 金融自律化는 加速化될 展望이다. 이러한 金融自律化의 물결은 기존 先進國 뿐만 아니라 開途國에까지 擴散되는 등 全世界的으로 普遍化되고 있는 趨勢이다. 따라서 본 硏究에서는 우리나라 生命保險會社들이 資産運用을 어떻게 하여왔는지를 考察한 후 향후 金融環境變化에 能動的으로 對處하기 위한 生命保險産業의 效率的인 資産運用方案을 提示하고자 한다. 본 論文의 構成은 序論에 이어 第2章에서는 資産運用에 대한 理論的 考寮로서 生命保險資産의 特性 및 資産運用의 基本的原則과 우리나라 生命保險會社의 資産運用에 있어 法的規制인 資産運用準則등의內容을 要約한다. 第3章에서는 우리나라 生命保險會社의 資産運用現況을 分析하고 問題點을 찾아본다. 第4章에서는 生命保險會社의 效率的인 資産運用方案을 經營管理側面, 法的規制緩和와 및 政府監督側面둥에서 살펴보고 ALM(Asset & Liability Management) 技法의 導入 필요성 및 綜合管理 시스템의 構築등을 摸索 하고자 한다
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디스플레이 화질개선을 위한 다수의 국부 색상 영역의 컬러교정 알고리즘 연구
The ideal color space is defined as a set of all colors that exists in the visible spectrum, which is known as standard color. The color of the displayed images, such as TVs, mobile phones, and monitors, which is distorted from differently than the color of the broadcast standard. The reason for this problem is that each of the displays has different color gamut. The most perfect way to solve these problems is to develop an ideal display that can represent all colors, but the current technical capability is limited. Therefore, it is necessary to the color calibration of the display in order to implement the broadcast standard color. In this paper, proposes algorithms to calibrate the color of the distorted color to the input broadcasting standard color of the display, that each of the displays has different color gamut. A study on color calibration algorithm of multiple local hue areas for display image quality improvement is designed to calibrate color by adjusting hue, luminance, and chroma of the three color attributes. The proposes color calibration algorithm is separately handling hue, luminance, and chroma in the YCbCr color space considering the perception of human eyes. Also, Calibrating the color with the broadcast standard color means modifying the original signal to match the characteristics of the display. Thus, it has effectively improved the quality of adverse factors by proposing compensation algorithms to improve the quality of unwanted side effects. Lastly, color calibration algorithm of display image quality enhancement was developed to minimize the H/W resource, and optimized for RTL coding.
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