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김유찬,김홍식,박향준,신용우,윤형근,정성훈 ( You Chan Kim,Hong Sik Kim,Hyang Joon Park,Yong Woo Cinn,Hyong Guen Yun,Sung Hoon Jung ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5
Keloids are benign fibrcus growths which extend beyond the original wound and rarely regress. Available methods of treatment include surgical excision, radiotherapy, intralesional steroid injection, cryotherapy, systemie. chemotherapy, zinc tape strapping, pressure, silicon gel and combined therapy. Postoperative irradiation is a useful and effective method of eradication or prevent.ion of keloid. We describe two cases of the prevention of keloids associated with post,operative irradiation. (Korean J Dermatol 1997;35(5): 1009-1012)
김유찬,전수일 ( You Chan Kim,Soo Il Chun ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1
The cutaneous mucinose are a group of connective disorders characterized by the deposition of mucin in the dermis. Thc disease may be a primary(metabolic) or secondary(catabolic). Secondary mucinosis is common in lupus erythematosus and dermatomyositis but rare in morphea. We report a case of guttate morphea with secondary cutaneous mucinosis. (Kor J Dermatol 1997;35(1): 165-168)
자외선을 조사한 C57BL Mice에서 자외선 조사부 및 차단부 표피내 멜라닌 세포의 변화에 관한 연구
김유찬,윤재일 ( You Chan Kim,Jai Il Youn ) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.3
In this experiment 40 adult male C57BL mice were used. The one ear of each animal was irradiated with high pressure mercury lamp (Burdick'UV-800) and the other ear was covered with nontransparent tape. Using split epidermal sheets treated with DOPA solution, a quatitiative study of epidermal melanocyte was carried out from the exposed and the shielded ear continuously on every second day during 14 daily exposures to 100 mJ/cm of UVB. The results were as follows : 1. Repeated radiation with ultraviolet light elicited a significant increase in population of melanocytes and the possible mechanism is a direct replication of the functioning melanocytes. 2. UVB irradiation induced increase in the number of epidermal melanocytes in covered ear as well as in irradiated ear. It is suggested that the population increase in the shielded skin is initiated by one or more systemic factors originating from the UVB irradiated skin.
Pathology ABC 2 (P 2) : Basic pathologic findings, mechanisms, and clinical correlation
김유찬 ( You Chan Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Although there are plenty of terminologies in the lexicon of dermatopathology, their precise definitions and clinical significance may easily be overlooked. The speaker tries to explain the following terminologies in terms of their definition, pathogenesis, clinical appearance and examples of dermatologic disorders: abscess, acantholysis, acanthosis, cartwheel appearance, cleft, colloid bodies/civatte bodies, degeneration, dyskeratosis, epithelioid, exocytosis, epidermotropism, fibrinoid degeneration, hydropic degeneration, granuloma, granulation tissue, Grenz zone, hypergranulosis, hyperkeratosis, karyorrhexis, leukocytoclasis, necrosis, parakeratosis, papillomatosis, pigmentary incontinence, spongiosis, eosinophilic spongiosis, squamous eddies, villus
김유찬(You Chan Kim),신용우(Yong Woo Cinn),이정화(Jeong Hwa Lee) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.1
Oil granuloma is a foreignbody reaction which occurs after injection of lipid usually for cosmetic or therapeutic reasons. I present a case of eyelid oil granuloma caused by accidental high pressure injury in a 39-year-old man. The patient had a 2 x 0.5cm sized, firm, normardear subcutaneous nodule on the Rt. upper eyelid. Histopathologic examination showed a characteris swiss-cheese appearance. Eyelid oil granuloma caused by high pressure injury is very rare and my case is the first described in Korean medical literatures. (Kor J Dermatol 1995; 33(1): 197-200)
DonSymposium 2-2-2 (SYP 2-2-2) : Intensified photodynamic therapy
김유찬 ( You Chan Kim ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Photodynamic therapy (PDT) involves the activation of a photosensitizer by visible light to create cytotoxic oxygen species and free radicals, which selectively destroy rapidly proliferating cells. PDT is increasingly being used in the treatment of oncologic conditions such as actinic keratosis (AK), basal cell carcinoma, and Bowen’s disease. There have been various studies for testing the efficacy and safety of PDT in treating AK. PDT is effective both as a lesion and field-directed treatment for AK. It has role where AK are multiple and/or confluent and at sites of poor healing. Efficacy is relatively poorer for acral lesions. Complete clearance rate of treated lesions, ranging from 59% to 91% at 3 months, after two treatment sessions has been obtained. In Asians the complete clearance rates of AK after PDT was lower than that of Caucasians. A possible explanation may be frequent pigmentation of AK lesions in Asians, which absorb and prevent the penetration of light. Cosmetic outcome following PDTfor AK is superior to cryotherapy. Treatment is generally well tolerated, but tingling discomfort or pain is common during PDT. A relative long incubation time is one of the disadvantages of PDT. Reduced discomfort and/or enhanced effectiveness have been observed with novel protocols including shorterphotosensitizer application times, in daylight PDT, BF-200 ALA: new photosensitizer, and fractional CO2 laser pretreatment. This presentation provides the effectiveness, side effects, and new method of PDT in AK lesions.
외과적 절제술로 호전된 신경종성 상피병을 보이는 신경섬유종증
김유찬 ( You Chan Kim ),이정화 ( Jeong Hwa Lee ),신용우 ( Young Woo Cinn ),정민 ( Min Chung ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.1
We report a case of elephantiasis neurofibromatosa in a 50-year-old female patient treated by in walking excision. She had difficulty in walking due to a huge mass on the abdomen. After surgical excision, she is leading a normal life and is very satisfied. (Kor J DErmatol 1996;34(1):136~140)