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Micro - Elisa 검사와 뇌전산화단층촬영으로 진단한 뇌실질 스파르가늠증 1 예
김철한(Chul Han Kim),박진현(Jin Hyun Park),김원천(Won Tsen Kim),이성수(Sung Soo Lee),한용표(Yong Pyo Han),한은경(Eun Kyung Han),최일생(Il Saing Choi) 대한내과학회 1989 대한내과학회지 Vol.37 No.5
N/A We report a case of intracerebral sparganosis diagnosed by micro-ELISA test and brain C-T scan. This 45-year-old male who had a history of having eaten frogs frequently, had suffered from uncontrolled headache with medication far about 1 year. Brain CT scan revealed a migrated low density lesion from Rt. temporo-parietal to Rt, frontal lobe. In cerebrospinal fluid, micro-ELISA test to sparganum was positive. Right frontal osteoplastic craniotomy was performed and a live sparganum mansoni was successfully removed from intracerebral region.
결핵성 뇌막염 진단에 있어서 뇌척수액 Adenosine Deaminase 활성도에 관한 연구
배선우(Seon Woo Bae),김원천(Won Tsen Kim),전근재(Geun Jae Jeon),성낙억(Nak Uk Sung),최경규(Kyung Gui Choi),최일생(Il Saing Choi) 대한내과학회 1988 대한내과학회지 Vol.34 No.4
N/A The prognosis of tuberculous meningitis is closely linked to the stage at which treatment is started. The cerebrospinal fluid findings, however, are often ambiguous, It has been suggested by recent investigations that ADA activities in cerebrospinal fluid may help differentiate tuberculous meningitis from aseptic meningitis. In this study, cerebrospinal fluid adenosine deaminase activities were measured in 23 cases of tuberculous meningitis, 9 cases of aseptic meningitis, 9 cases of purulent meningitis, 24 cases of miscellaneous neurologic conditions and 23 cases of normal controls. The results obtained were as follows: 1) The mean ADA activity in tuberculous meningitis was 17.39±10,34 U/L, in bacterial meningitis 7.87±8.52 U/L, in aseptic meningitis 2.83±1.92U/L, in miscellaneous neurologic conditions 2.80±5.61U/L and in control 1,09±0.51U/L. 2) The ADA activitiies in tuberculous meningitis showed significantly higher values than in other groups (P<0.001), 3) Cerebrospinal fluid ADA activities differentiated tuberculous meningitis from those with aseptic meningitis being higher than 4.5U/L in all and higher than 6.5U/L in 96% case of tuberculous meningitis, but lower than 6,5U/L in aseptic meningitis and less than 3.5U/L in normal controls. 4) In tuberculous meningitis, ADA activities showed significant correlation with protein in cerebrospinal fluid (P<0.01), but in other groups, no significant correlation with available routine parameters in cerebrospinal fluid. It is suggested that measurement of ADA activity in cerebrospinal fluid is a available test which is relatively easily performed for diagnosis of tuberculous meningitis, especially differential diagnosis with aseptic meningitis.
한국 정상성인 혈장 β-Endorphin 치에 관한 연구
김원천 대한내과학회 1986 대한내과학회지 Vol.31 No.4
β-endorphin, a petide of 31 amino acid which was known as endogenous opium in human seemed to play the significant role both physiologic and. pathophysiologic conditions. For the study of its- function, it must be measured normal values in plasma of healthy persons. This research focused it and gained result as follows. 1) In male, the values of p-endorphin ranges from 2.5pmol/l to 8.9pmol/l with mean values- was 6.173±0.335pmol/l. 2) In female, the values of p-endorphin ranges from 0.6pmol/l to 8.9pmol/l with the mean values was 4.553±0.443pmol/l, 3) Observing diurnal rhythm among 7males and 5 females, there was no significant change within a day(p<0.05)