경상북도 농업기술원 이전을 위한 입지여건 분석

김원정,권오성,장경수,여준호,Kim, Won-Jeong,Kwon, O-Sung,Jang, Kyung-Su,Yeo, Jun-Ho 경북대학교 농업과학기술연구소 2015 慶北大農學誌 Vol.33 No.1

기후변화, 농업용수, 대기오염 등의 환경변화에 민감한 연구단지의 특성상 환경 자원의 이용이 용이해야 하나 현 농업기술원은 농업연구를 위한 환경 및 생태계 유지가 힘든 실정이다. 또한 지속 가능한 농업, 6차 산업화와 같은 새로운 패러다임에 입각한 기반시설을 수립하고 공공서비스의 효율적인 공급을 위해서는 경상북도농업기술원의 이전이 불가피하다. 이에 따라 농업기술원 이전을 위한 입지이론 및 방법을 검토하고 입지여건 분석을 위한 입지선정 기준을 제시하는 것이 본 연구의 목적이다. 따라서, 먼저 공공시설 이전에 관한 입지이론에 대해 알아보았고, 입지선정을 위한 연구방법으로 후보지 여과방법을 사용하였다. 후보지 여과방법에는 요인별 점검법, 나뭇가지 모양분석법, 혼합형 분석법이 있는데 본 연구에서는 요인별 점검법을 바탕으로 하여 입지기준을 제시하였다. 이에 따라 입지선정 기준으로 경제성과 개발의 용의성, 접근성과 편의성, 농업여건, 토양여건, 인력자원 지원이 가능한 곳 그리고 연계성과 형평성이 고려되었다. Due to various environmental changes, the current location of the Gyeongsangbuk-do Agricultural Research & Extension Services needs to be changed to provide an appropriate environment and ecosystem for agricultural research and the efficient provision of public services. Accordingly, this study proposes a standard for selecting the new location. First, the location theory for the transfer of public facilities is investigated, and candidate filtration methods considered for the location selection. The candidate filtration methods include a component inspection, branch shape analysis, and mixed analysis. This study uses a component inspection, where the component criteria include the economic feasibility and ease of development, accessibility and convenience, agricultural conditions, soil conditions, connectivity, fairness, and human resource-richness of the region.

패킷 손실이 발생하는 네트워크 환경에서의 H.264의 FMO 성능분석과 비교에 관한 연구

김원정,임혜숙,임창훈,Kim Won-Jung,Lim Hye-Sook,Yim Chang-Hoon 한국통신학회 2006 韓國通信學會論文誌 Vol.31 No.5C

H.264 is the most recent video coding standard, containing improved error resilience tools than previous video compression schemes. This paper shows an analysis of the dependency of error concealment (EC) performance on the expected number of correctly received neighboring macroblock(MB)s for a lost MB, applying error concealment schemes to the raster scan mode that is used in the previous video coding standard and the flexible macroblock ordering (FMO) which is one of error-resilience tools in H.264. We also present simulation results and performance evaluation with various packet loss rates. Simulation results show that the FMO mode provides better EC performances of $1{\sim}9dB$ PSNR improvements compared to the raster scan mode because of larger expected number of correctly received neighboring MBs. The PSNR improvement by FMO mode becomes higher as the intra-frame period is larger and the packet loss rate is higher. H.264는 현재 IP를 기반으로 하는 유무선 네트워크분야에서 많은 관심을 받고 있는 표준으로서 기존에 제정된 비디오 표준들보다 향상된 에러 복구 기술들을 포함하고 있다. 본 논문에서는 기존의 비디오 표준에서 사용되어 오던 raster scan 방식과 H.264의 에러 복구 기술들 중 하나인 FMO (flexible macroblock ordering) 방식에 에러 은닉 기술을 적용하여 에러 은닉의 성능이 정확히 온 인접한 매크로블락 수에 따라 좌우됨을 분석하고, 다양한 패킷 손실율에서의 성능을 보인다. 시뮬레이션 결과, FMO 방식이 raster scan 방식에 비해 손실없이 오는 인접한 매크로블락 수가 많아 에러 은닉에 의한 PSNR 성능이 $1{\sim}9dB$ 정도 향상되고, 특히 인트라 프레임 간격이 길고 패킷 손실율이 높은 경우에 FMO 방식에 의한 PSNR 성능 향상이 더 크다.

한국인 아토피피부염, 건선, 만성특발두드러기 환자에서 임상적 중증도와 혈중 비타민 D 농도와의 연관성

김원정 ( Won Jeong Kim ),김준영 ( Jun Young Kim ),박민영 ( Min Young Park ),송마가렛 ( Margaret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.3

Background: Deficiency of vitamin D is reported to be an important factor associated with various dermatoses such as atopic dermatitis, psoriasis, urticaria, and skin cancers. However, this association is disputable and has not been clarified. Objective: To evaluate the status of serum 25-hydroxyvitamin D in patients with atopic dermatitis, psoriasis, and chronic urticaria, and examine the relationship between vitamin D levels and disease severity/activity compared with sex- and age-matched healthy controls. Methods: A cross-sectional study of 23, 34, and 73 patients with atopic dermatitis, psoriasis, and chronic idiopathic urticaria, respectively, and sex- and age-matched controls was conducted. Objective severity scoring of atopic dermatitis (eczema area and severity index) and psoriasis (psoriasis area and severity index), the urticaria activity score, and serum 25-hydroxyvitamin D levels were measured for each subject. Results: Serum 25-hydroxyvitamin D levels were significantly lower in atopic dermatitis patients than those in the controls (p<0.05). However, mean vitamin D levels in psoriasis and chronic idiopathic urticaria patients were not significantly lower than those in the controls (p>0.05). Furthermore, no significant inverse correlation was found between disease severity and serum 25-hydroxyvitamin D levels in atopic dermatitis, psoriasis, and chronic idiopathic urticaria patients (p>0.05). Conclusion: The impact of vitamin D in these dermatoses seems to be overestimated and needs further study to prove any true association. (Korean J Dermatol 2015;53(3):209∼216)

임신 중 대상포진 환자의 임상양상 및 대상포진이 주산기 예후에 미치는 영향

김원정 ( Won Jeong Kim ),김준영 ( Jun Young Kim ),이원주 ( Weon Ju Lee ),이석종 ( Seok Jong Lee ),김도원 ( Do Won Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.11

Background: Varicella during pregnancy can affect both the mother and their baby and cause serious complications. However, reports of herpes zoster in pregnancy are relatively uncommon. Objective: We wanted to investigate the clinical manifestations of herpes zoster during pregnancy and its impact on the perinatal outcome. Methods: From 2006 to 2010, a total of 38 pregnant and 40 non-pregnant women with herpes zoster were included for the investigation of the dermatomal distribution, the characteristics and degree of pain, the treatment modalities and the complications. In a pregnant group, we also checked the gestational age and parity at the time of disease onset, the delivery methods, the fetal birth weight and height, the congenital abnormalities and the occurrence of the congenital varicella syndrome, neonatal varicella or zoster within 1 month after birth. Results: There was no significant difference in the anatomical distribution of herpes zoster in both groups. The mean severity of initial pain was significantly increased during pregnancy (p=0.039). Only 11 pregnant women (28.9%) took antiviral agents or systemic analgesics, whereas 26 in the control group (65.0%) took these medications. Compared to the 4 in the control group (10.0%), 3 pregnant patients (7.9%) experienced postherpetic neuralgia, but with no other serious complications. Congenital varicella syndrome and neonatal varicella or zoster was not found. Conclusion: Pregnancy does not seem to exert a detrimental impact on herpes zoster and maternal zoster seems to have no harmful effects on neonates. (Korean J Dermatol 2010;48(11):941∼947)

등에 발생한 원발성 피부 상피양 혈관내피세포종

김원정 ( Won Jeong Kim ),박현제 ( Hyun Je Park ),김훈수 ( Hoon Soo Kim ),진현우 ( Hyun Woo Chin ),김수한 ( Su Han Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.3

Epithelioid hemangioendothelioma (EHE) is an uncommon vascular neoplasm that is considered to be a low-grade malignancy with a severity between an angiolymphoid hyperplasia with eosinophilia and an epithelioid hemangiosarcoma. The appearance of cutaneous EHE is extremely rare and only about 20 cases have been reported in the Korean and English literatures. A 70-year-old man presented with an approximately 1-year history of an isolated painful subcutaneous nodule of the back. A histopathologic examination revealed nests and cords of epithelioid eosinophilic cells in hyalinized stroma with intracytoplasmic vacuoles. Tumor cells were strongly positive for the endothelial cell markers CD31 and CD34, and we didn`t find any metastatic lesions under radiologic examination. On the basis of these findings, the diagnosis of primary cutaneous EHE was made. To our knowledge, cutaneous EHEs were reported in only 2 cases in the Korean literature, and that of the trunk has not been published previously. Moreover, there is no meta-analytic study about cutaneous EHE. So, we report here a rare case of EHE of the back and review the relevant literature. (Korean J Dermatol 2011;49(3):269∼273)

손발톱진균증으로 오진 후 항진균제가 투여된 손발톱질환에 대한 임상적 연구

김원정 ( Won Jeong Kim ),송마가렛 ( Margaret Song ),김훈수 ( Hoon Soo Kim ),김수한 ( Su Han Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.5

Background: Treatment of onychomycosis should be commenced after mycological confirmation due to the side effects and long duration of oral antifungal agents. However, many doctors treat patients with nail disorders that resemble onychomycosis without any mycological examination (ME) in clinical practice. Objective: To investigate the various nail disorders misdiagnosed as onychomycosis and to evaluate the performing ratios of appropriate diagnostic procedures of onychomycosis. Methods: The study was performed in a total of 48 patients who had a history of being misdiagnosed and treated for onychomycosis. We investigated the characteristics of each patient, the specialty of their previous doctor, and their previous treatment modality and duration. Whether or not they had previously received proper diagnostic procedures was also investigated. All of the data were collected by questionnaires, and their final diagnoses were also recorded. Results: Among the 48 patients, 31 (31/48, 64.7%) were female, and the mean age of the patients was 45.5±15.7. Eighteen patients (18/48, 37.5%) were referred from dermatologists and 30 (30/48, 65.2%) from non-dermatologists. The results of the questionnaires revealed that only 10 of the dermatologists (10/18, 55.6%) performed ME before initiating treatment for onychomycosis, and none of the non-dermatologists did it. The duration of incorrect previous systemic anti-fungal treatment was also significantly longer when administered by non-dermatologists as compared with dermatologists (p=0.042), and over half of the patients (30/46, 65.2%) were treated with fluconazole. Onycholysis (22/48, 45.8%) and trachyonychia (18/48, 37.5%) were the most common final diagnoses, but various nail disorders such as pitting nail, median nail dystrophy, and subungual melanoma were also included. Conclusion: To avoid misdiagnosis and incorrect anti-fungal treatment, people with nail disorders that resemble onychomycosis should be recommended to visit dermatologists, and the doctors should perform appropriate mycological examinations in these patients. (Korean J Dermatol 2011;49(5):408∼414)

타이로시나제 유전자 돌연변이로 인한 눈피부백색증

김원정 ( Won Jeong Kim ),김수한 ( Su Han Kim ),정도상 ( Do Sang Jung ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),권경술 ( Kyung Sool Kwon ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.11

Oculocutaneous albinism (OCA) is a group of inherited disorders of the melanin synthesizing system, and these are characterized by hypopigmentation of the hair, skin and eyes, with a normal number of melanocytes. The defect of melanin biosynthesis is caused by genetic mutation of such enzymes as tyrosinase (TYR), and tyrosinase-related protein (TYRP), which affect tyrosine convert to melanin pigment. There are at least four types of OCA from OCA1 to OCA4. The different types of OCA are caused by mutations in different genes. The most severe form, OCA1A, is distinguishable from other forms owing to a complete lack of melanin pigment throughout the patient`s whole life. But among other types, except OCA1A, it is hard to identify the correct type according to only the clinical findings because their clinical phenotypes usually overlap. Therefore, molecular study is a useful tool for the typing and diagnosis of OCA. We experienced a case of a 10-month-old male toddler who has pale skin, straw-colored hair, nystagmus and visible choroidal vessels. Under the clinical impression of OCA, the correct subtyping was made on the basis of genetic analysis of the chromosomes and we found a new TYR gene frame-shift mutation. (Korean J Dermatol 2009;47(11):1291~1295)

어른에 발생한 Porokeratotic Eccrine Ostial and Dermal Duct Nevus와 Dermoscopy 소견

김원정 ( Won Jeong Kim ),송마가렛 ( Margaret Song ),좌승욱 ( Seung Wook Jwa ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.6

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare disorder of keratinization, involving acrosyringium. Most cases were congenital, and showed linear distribution of multiple hyperkeratotic comedo-like papules and plaques located on acral extremities. Adult-onset cases were extremely rare in the English literatures and there have not been any reported cases in the Korean literatures. Moreover, there has been no report describing the dermoscopic features of PEODDN so far. So, we here report a rare case of adult-onset PEODDN with its dermoscopic finding and review of the relevant literatures.

비배양 표피세포이식술을 이용한 국소 부위 백반증의 치료

김준영 ( Jun Young Kim ),김원정 ( Won Jeong Kim ),이원주 ( Weon Ju Lee ),이석종 ( Seok Jong Lee ),김도원 ( Do Won Kim ),나건연 ( Gun Yoen Na ),김병수 ( Byung Soo Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.5

A woman aged 40 years presented with symmetric band of depigmented patches on her hand dorsum and forearms. Under the diagnosis of focal vitiligo, we initially treated her with oral and topical steroids and local UVB irradiation. However, the wrist lesions were recalcitrant. Therefore, we tried a non-cultured epidermal cellular graft using autologous melanocyte-keratinocyte suspension. Twelve months after the procedure, higher than 70% of repigmentation was observed. This procedure seems to be an effective and practical treatment for recalcitrant vitiliginous lesions. (Korean J Dermatol 2011;49(5):448∼451)

안드로겐탈모증에 사용되는 보완대체의학에 관한 예비연구

김준영 ( Jun Young Kim ),김원정 ( Won Jeong Kim ),김호연 ( Ho Youn Kim ),이원주 ( Weon Ju Lee ),이석종 ( Seok Jong Lee ),김도원 ( Do Won Kim ),김병수 ( Byung Soo Kim ),황보민 ( Bo Min Hwang ),서형식 ( Hyung Sik Seo ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7

Background: Use of treatments categorized as complementary and alternative medicine (CAM) have increased considerably in the field of dermatology. However, most studies have been focused on atopic dermatitis and psoriasis, and little is known of the prevalence of use of CAM in patients with androgenetic alopecia (AGA). Objective: We aimed to determine the frequency, type, duration, and factors associated with the use of CAM in the treatment of AGA at a dermatologic outpatient clinic. Methods: AGA patients at the outpatient clinic (n=151) received a face-to-face structured questionnaire covering 5 types of CAM plus an open alternative labeled ``other type``. Results: Overall 70.2% (106/151) of the subjects with AGA reported the current or previous use of at least 1 CAM. Topical application (85, 56.3%) was most frequently used, followed by diet therapy (35, 23.2%), health food supplements (15, 9.9%), massage therapy (13, 8.6%), and Oriental medicine (10, 6.6%). With respect to the reasons for using CAM, ``recommendation by people around the patient`` (59.4%) was most commonly chosen by the patients. The subjective therapeutic effect and satisfaction with CAM were the best with health food supplements and topical application (80.0% and 21.1%, respectively). Conclusion: As our results indicate that the use of CAM continues to rise by patients with AGA, the need for reliable sources of information about specific CAM therapies becomes more essential. To assist AGA patients in selecting proper treatment modalities, further longitudinal and controlled studies are required to assess the efficacy and safety of CAM.