경상북도 농업기술원 이전을 위한 입지여건 분석

김원정,권오성,장경수,여준호,Kim, Won-Jeong,Kwon, O-Sung,Jang, Kyung-Su,Yeo, Jun-Ho 경북대학교 농업과학기술연구소 2015 慶北大農學誌 Vol.33 No.1

기후변화, 농업용수, 대기오염 등의 환경변화에 민감한 연구단지의 특성상 환경 자원의 이용이 용이해야 하나 현 농업기술원은 농업연구를 위한 환경 및 생태계 유지가 힘든 실정이다. 또한 지속 가능한 농업, 6차 산업화와 같은 새로운 패러다임에 입각한 기반시설을 수립하고 공공서비스의 효율적인 공급을 위해서는 경상북도농업기술원의 이전이 불가피하다. 이에 따라 농업기술원 이전을 위한 입지이론 및 방법을 검토하고 입지여건 분석을 위한 입지선정 기준을 제시하는 것이 본 연구의 목적이다. 따라서, 먼저 공공시설 이전에 관한 입지이론에 대해 알아보았고, 입지선정을 위한 연구방법으로 후보지 여과방법을 사용하였다. 후보지 여과방법에는 요인별 점검법, 나뭇가지 모양분석법, 혼합형 분석법이 있는데 본 연구에서는 요인별 점검법을 바탕으로 하여 입지기준을 제시하였다. 이에 따라 입지선정 기준으로 경제성과 개발의 용의성, 접근성과 편의성, 농업여건, 토양여건, 인력자원 지원이 가능한 곳 그리고 연계성과 형평성이 고려되었다. Due to various environmental changes, the current location of the Gyeongsangbuk-do Agricultural Research & Extension Services needs to be changed to provide an appropriate environment and ecosystem for agricultural research and the efficient provision of public services. Accordingly, this study proposes a standard for selecting the new location. First, the location theory for the transfer of public facilities is investigated, and candidate filtration methods considered for the location selection. The candidate filtration methods include a component inspection, branch shape analysis, and mixed analysis. This study uses a component inspection, where the component criteria include the economic feasibility and ease of development, accessibility and convenience, agricultural conditions, soil conditions, connectivity, fairness, and human resource-richness of the region.

경기육괴 남서부 고군산군도 지역의 신원생대 화성암과 퇴적암의 형성시기 및 지구조환경

김원정(Won Jeong Kim),오창환(Chang Whan Oh) 한국암석학회 2020 한국암석학회 학술발표회 논문집 Vol.2020 No.8

등에 발생한 원발성 피부 상피양 혈관내피세포종

김원정 ( Won Jeong Kim ),박현제 ( Hyun Je Park ),김훈수 ( Hoon Soo Kim ),진현우 ( Hyun Woo Chin ),김수한 ( Su Han Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.3

Epithelioid hemangioendothelioma (EHE) is an uncommon vascular neoplasm that is considered to be a low-grade malignancy with a severity between an angiolymphoid hyperplasia with eosinophilia and an epithelioid hemangiosarcoma. The appearance of cutaneous EHE is extremely rare and only about 20 cases have been reported in the Korean and English literatures. A 70-year-old man presented with an approximately 1-year history of an isolated painful subcutaneous nodule of the back. A histopathologic examination revealed nests and cords of epithelioid eosinophilic cells in hyalinized stroma with intracytoplasmic vacuoles. Tumor cells were strongly positive for the endothelial cell markers CD31 and CD34, and we didn`t find any metastatic lesions under radiologic examination. On the basis of these findings, the diagnosis of primary cutaneous EHE was made. To our knowledge, cutaneous EHEs were reported in only 2 cases in the Korean literature, and that of the trunk has not been published previously. Moreover, there is no meta-analytic study about cutaneous EHE. So, we report here a rare case of EHE of the back and review the relevant literature. (Korean J Dermatol 2011;49(3):269∼273)

손발톱진균증으로 오진 후 항진균제가 투여된 손발톱질환에 대한 임상적 연구

김원정 ( Won Jeong Kim ),송마가렛 ( Margaret Song ),김훈수 ( Hoon Soo Kim ),김수한 ( Su Han Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.5

Background: Treatment of onychomycosis should be commenced after mycological confirmation due to the side effects and long duration of oral antifungal agents. However, many doctors treat patients with nail disorders that resemble onychomycosis without any mycological examination (ME) in clinical practice. Objective: To investigate the various nail disorders misdiagnosed as onychomycosis and to evaluate the performing ratios of appropriate diagnostic procedures of onychomycosis. Methods: The study was performed in a total of 48 patients who had a history of being misdiagnosed and treated for onychomycosis. We investigated the characteristics of each patient, the specialty of their previous doctor, and their previous treatment modality and duration. Whether or not they had previously received proper diagnostic procedures was also investigated. All of the data were collected by questionnaires, and their final diagnoses were also recorded. Results: Among the 48 patients, 31 (31/48, 64.7%) were female, and the mean age of the patients was 45.5±15.7. Eighteen patients (18/48, 37.5%) were referred from dermatologists and 30 (30/48, 65.2%) from non-dermatologists. The results of the questionnaires revealed that only 10 of the dermatologists (10/18, 55.6%) performed ME before initiating treatment for onychomycosis, and none of the non-dermatologists did it. The duration of incorrect previous systemic anti-fungal treatment was also significantly longer when administered by non-dermatologists as compared with dermatologists (p=0.042), and over half of the patients (30/46, 65.2%) were treated with fluconazole. Onycholysis (22/48, 45.8%) and trachyonychia (18/48, 37.5%) were the most common final diagnoses, but various nail disorders such as pitting nail, median nail dystrophy, and subungual melanoma were also included. Conclusion: To avoid misdiagnosis and incorrect anti-fungal treatment, people with nail disorders that resemble onychomycosis should be recommended to visit dermatologists, and the doctors should perform appropriate mycological examinations in these patients. (Korean J Dermatol 2011;49(5):408∼414)

타이로시나제 유전자 돌연변이로 인한 눈피부백색증

김원정 ( Won Jeong Kim ),김수한 ( Su Han Kim ),정도상 ( Do Sang Jung ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),권경술 ( Kyung Sool Kwon ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.11

Oculocutaneous albinism (OCA) is a group of inherited disorders of the melanin synthesizing system, and these are characterized by hypopigmentation of the hair, skin and eyes, with a normal number of melanocytes. The defect of melanin biosynthesis is caused by genetic mutation of such enzymes as tyrosinase (TYR), and tyrosinase-related protein (TYRP), which affect tyrosine convert to melanin pigment. There are at least four types of OCA from OCA1 to OCA4. The different types of OCA are caused by mutations in different genes. The most severe form, OCA1A, is distinguishable from other forms owing to a complete lack of melanin pigment throughout the patient`s whole life. But among other types, except OCA1A, it is hard to identify the correct type according to only the clinical findings because their clinical phenotypes usually overlap. Therefore, molecular study is a useful tool for the typing and diagnosis of OCA. We experienced a case of a 10-month-old male toddler who has pale skin, straw-colored hair, nystagmus and visible choroidal vessels. Under the clinical impression of OCA, the correct subtyping was made on the basis of genetic analysis of the chromosomes and we found a new TYR gene frame-shift mutation. (Korean J Dermatol 2009;47(11):1291~1295)

어른에 발생한 Porokeratotic Eccrine Ostial and Dermal Duct Nevus와 Dermoscopy 소견

김원정 ( Won Jeong Kim ),송마가렛 ( Margaret Song ),좌승욱 ( Seung Wook Jwa ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.6

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare disorder of keratinization, involving acrosyringium. Most cases were congenital, and showed linear distribution of multiple hyperkeratotic comedo-like papules and plaques located on acral extremities. Adult-onset cases were extremely rare in the English literatures and there have not been any reported cases in the Korean literatures. Moreover, there has been no report describing the dermoscopic features of PEODDN so far. So, we here report a rare case of adult-onset PEODDN with its dermoscopic finding and review of the relevant literatures.

임신 중 대상포진 환자의 임상양상 및 대상포진이 주산기 예후에 미치는 영향

김원정 ( Won Jeong Kim ),김준영 ( Jun Young Kim ),이원주 ( Weon Ju Lee ),이석종 ( Seok Jong Lee ),김도원 ( Do Won Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.11

Background: Varicella during pregnancy can affect both the mother and their baby and cause serious complications. However, reports of herpes zoster in pregnancy are relatively uncommon. Objective: We wanted to investigate the clinical manifestations of herpes zoster during pregnancy and its impact on the perinatal outcome. Methods: From 2006 to 2010, a total of 38 pregnant and 40 non-pregnant women with herpes zoster were included for the investigation of the dermatomal distribution, the characteristics and degree of pain, the treatment modalities and the complications. In a pregnant group, we also checked the gestational age and parity at the time of disease onset, the delivery methods, the fetal birth weight and height, the congenital abnormalities and the occurrence of the congenital varicella syndrome, neonatal varicella or zoster within 1 month after birth. Results: There was no significant difference in the anatomical distribution of herpes zoster in both groups. The mean severity of initial pain was significantly increased during pregnancy (p=0.039). Only 11 pregnant women (28.9%) took antiviral agents or systemic analgesics, whereas 26 in the control group (65.0%) took these medications. Compared to the 4 in the control group (10.0%), 3 pregnant patients (7.9%) experienced postherpetic neuralgia, but with no other serious complications. Congenital varicella syndrome and neonatal varicella or zoster was not found. Conclusion: Pregnancy does not seem to exert a detrimental impact on herpes zoster and maternal zoster seems to have no harmful effects on neonates. (Korean J Dermatol 2010;48(11):941∼947)

한국인 아토피피부염, 건선, 만성특발두드러기 환자에서 임상적 중증도와 혈중 비타민 D 농도와의 연관성

김원정 ( Won Jeong Kim ),김준영 ( Jun Young Kim ),박민영 ( Min Young Park ),송마가렛 ( Margaret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.3

Background: Deficiency of vitamin D is reported to be an important factor associated with various dermatoses such as atopic dermatitis, psoriasis, urticaria, and skin cancers. However, this association is disputable and has not been clarified. Objective: To evaluate the status of serum 25-hydroxyvitamin D in patients with atopic dermatitis, psoriasis, and chronic urticaria, and examine the relationship between vitamin D levels and disease severity/activity compared with sex- and age-matched healthy controls. Methods: A cross-sectional study of 23, 34, and 73 patients with atopic dermatitis, psoriasis, and chronic idiopathic urticaria, respectively, and sex- and age-matched controls was conducted. Objective severity scoring of atopic dermatitis (eczema area and severity index) and psoriasis (psoriasis area and severity index), the urticaria activity score, and serum 25-hydroxyvitamin D levels were measured for each subject. Results: Serum 25-hydroxyvitamin D levels were significantly lower in atopic dermatitis patients than those in the controls (p<0.05). However, mean vitamin D levels in psoriasis and chronic idiopathic urticaria patients were not significantly lower than those in the controls (p>0.05). Furthermore, no significant inverse correlation was found between disease severity and serum 25-hydroxyvitamin D levels in atopic dermatitis, psoriasis, and chronic idiopathic urticaria patients (p>0.05). Conclusion: The impact of vitamin D in these dermatoses seems to be overestimated and needs further study to prove any true association. (Korean J Dermatol 2015;53(3):209∼216)

시계열분석을 통한 아파트매매가격지수와 타 거시경제 변수들과의 상호관계 분석

김원정(Kim, Won-Jeong),여준호(Yeo, Jun-Ho) 한국경제통상학회 2017 경제연구 Vol.35 No.1

본 연구는 최근 급변한 한국의 부동산시장과 이에 영향을 미치는 변수들 간의 상호관계를 분석해보고자 하였으며, 연구 수행을 위해 2003년 1월부터 2015년 12월까지 월별데이터를 이용하였다. 먼저 시계열 자료의 안정성여부를 파악하기 위해 단위근 검정을 실시하였으며 그 결과 단위근이 존재하는 것으로 나타나 1차 차분한 시계열 데이터를 사용하였다. 다음으로 공적분 검정을 실시하였고 그 결과 공적분관계가 존재함이 확인 되었기에 오차수정항을 고려한 VEC모형을 선택하여 분석을 진행하였다. 오차수정모형의 장기균형관계식을 통해 확인한 결과, 한국 주택담보대출금리 1%의 증가로 인해 아파트 매매가격지수는 –1.08% 감소하였고, 종합주가지수 1 %증가는 아파트매매가격지수를 0.23% 증가시켰다. 우리나라 국내총생산의 경우 GDP 1% 증가하면 아파트 매매가격지수는 1.92% 증가하는 것으로 나타났으며, 마지막으로 미국 주택담보대출금리의 경우 1% 증가할 때 우리나라 아파트 매매가격지수는 –0.04% 감소하는 것으로 나타났다. This study analyzed relationship between trading price index of apartment and other macroeconomic variables using multivariate time series analysis. To do this, we used monthly data taken from trading price index of apartment, mortgage rate of korea and USA, real GDP and KOSPI over the period January of 2003 to December of 2015. First, we conducted Unit Root Test to confirm stability of time series data. As a result, there are Unit Roots so we used data of First Order Differenced. Second, we conducted Cointegration Test. As a result, there are Cointegrations among the five variables, so we set the Error Correction Model. We estimated coefficients from the Vector Error Correction Model at the AR 3 using Akaike’s Information Criteria. The results show that 1% increase of korea’s mortgage rate lead 1.08% decrease of apartment purchase price indices, 1% increase of KOSPI lead 0.23% increase of trading price index of apartment, 1% increase of real GDP lead 1.92% increase of trading price index of apartment and 1% increase of USA’s mortgage rate lead 0.04% decrease of trading price index of apartment.

고군산군도지역의 신원생대 방축도층과 이를 관입한 화성암의 형성시기 및 지구조환경

김원정(Won Jeong Kim),오창환(Chang Whan Oh),이승환(Seung Hwan Lee),김진석(Jin Seok Kim),신명호(Myeong Ho Shin),정지완(Ji Wan Jeong) 한국암석학회 2019 한국암석학회 학술발표회 논문집 Vol.2019 No.5