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자동차 제조회사 근로자를 대상으로 흡연과 스트레스 지수 및 혈관노화도와의 관계
김승모,정현정,Kim, Seung-Mo,Jung, Hyun-Jung 대한예방한의학회 2013 대한예방한의학회지 Vol.17 No.2
Objectives : This study investigated the relationship between smoking and health factors including stress resistance, stress index, fatigue and vaso-aging degree. Methods : The subjects were 19,953 persons who had received health examination by Korean Medicine and submitted questionnaires about smoking history, for 8 months from March to November in 2011. The stress index and resistance, fatigue were measured by HRV(Heart Rate Variability). The vaso-aging degree were measured by APG(Accelerated Photoplethysmograph). Results : Regarding the relationship between smoking and stress index and resistance, fatigue and vaso-aging degree were significant differences(p<0.05). Conclusions : This study suggests that smoking affects health factors including stress, fatigue and avaso-aging degree.
시호(柴胡)가 총담관결찰 및 taurocholate 부하(負荷) 흰쥐 간의 MAO 활성에 미치는 영향
김승모,왕오호,박재현,Kim, Seong-Mo,Wang, Wu-Hao,Park, Jae-Hyun 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.2
Object : This study was carried out to examine the effect of Bupleuri Radix on experimental cholestasis, and make clear apart of this mechanism. Methods : Two models of common bile duct ligation group and taurocholate load group after common bile duct ligation were induced, and Bupleuri Radix extract was taken orally for 14 days. In the 1, 2, 4, 7 and 14 days after treatment, the mitochondrial and microsomal monoamine oxidase(MAO) A and B activities in liver were measured. Results : The mitochondrial MAO A and B activities increased in both Blupleuri Radix treated group after common bile duct ligation and Blupleuri Radix treated group after taurocholate load and common bile duct ligation. MAO A increased in Blupleuri Radix treated group after taurocholate load and common bile duct ligation, and MAO B increased in Blupleuri Radix treated group after common bile duct ligation. The microsomal MAO A activities increased in both Blupleuri Radix treated group after common bile duct ligation and Blupleuri Radix treated group after taurocholate load and common bile duct ligation. Conclusion : According to the result, it is consider that Blupleuri Radix not only improves cholestatis in liver, but also decreases a genetic synthesis of taurocholic acid.
사염화탄소의 장기(長期) 투여(投與)로 유발된 백서(白鼠) 간경변(肝硬變)에 대한 형방지황탕(荊防地黃湯)의 조직병리학적 영향
김승모,Kim, Seong-Mo 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.2
Objective : This study was carried out to investigate the effects of oral administration of Hyeungbangjihwang-tang (HBJHT) on the liver cirrhosis of rats induced by Carbon tetrachloride for 10 weeks. Method : The histopathological changes were observed. The HBJHT extracts were daily dosed at 50, 100 and 200mg/kg for 12 weeks. Results : Severe hepatocellular necrosis and ballooning, hyperplasia of connective tissue, subdued reduction of hepatic lobule, and hyperplasia of bile duct in portal triad were dramatically decreased in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group in histopathological observation. The diameter of hepatic lobules was significantly enlarged in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group, and the amounts of connective tissue, degenerative cells and bile ducts were significantly and dose-dependently decreased. Conclusion : It is concluded that HBJHT has a significant recovering effect on the liver of rats induced by carbon tetrachloride.
김승모,이유리,조나경,최홍식,김경순,Kim, Seung-mo,Lee, Yu-ri,Cho, Na-kyung,Choi, Hong-sik,Kim, Kyung-soon The Society of Internal Korean Medicine 2021 大韓韓方內科學會誌 Vol.42 No.4
본 연구는 B형 및 C형 간염에 대한 한약 치료의 효과를 평가하기 위해 무작위 임상연구를 대상으로 체계적 문헌고찰 및 메타분석을 시행하였다. 검색엔진은 EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, Oasis database를 이용하였으며 국내의 검색 엔진 키워드는 '간염' 또는 '바이러스성간염', '한약', '무작위 배정 임상시험'을, 국외 검색 엔진 키워드는 'hepatitis' or 'viral hepatitis' and 'herbal medicine' or 'traditional chinese medicine' and 'randomized controlled trial'을 이용하였다. 연구 결과 15개의 무작위배정 임상시험을 선택되었으며, 그 중 통계적으로 유의미한 결과를 나타낸 연구는 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 HBV DNA loss에서 높은 효과를 보였다. 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 HBeAg loss에서 통계적으로 유의한 효과를 보였으며, 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 ALT가 감소하였다. 본 연구는 B형 및 C형 간염환자를 대상으로 한약의 효과를 확인하기 위해 기존에 시행된 RCT 연구를 대상으로 체계적 문헌고찰을 시행하였으며, 한약과 양약의 복합치료가 양약 단독치료에 비해 치료효과가 더 높은 것으로 나타났다. The aim of this study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) that applied herbal medicine to treat viral hepatitis B and C in order to determine the therapeutic efficacy of herbal medicine. EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, and Oasis databases were searched to identify RCTs. The selected studies were assessed by the Cochrane group's risk of bias tool. A total of 15 RCTs were selected, and the hepatitis B virus (HBV) DNA reduction was significantly higher in patients treated with herbal medicine combined with Western medicine than in patients treated with herbal medicine. Herbal medicine combined with Western medicine was also superior to Western medicine alone in achieving hepatitis B e-antigen (HBeAg) and alanine aminotransferase [ALT] reduction. Only herbal medicine alone was not superior to Western medicine treatments in achieving HBV DNA, HBeAg, and ALT reduction.
적외선 가연성가스 센서의 입출력 특성 및 캘리브레이션 연구
김승모(Seungmo Kim),박규태(Gyoutae Park),김병덕(Byuongduk Kim),조영도(Youngdo Jo),김희식(Hiesik Kim) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.11
In this paper, we conducted a study of the calibration to grasp the input and output characteristics of the two types of gas sensors to be used in a flammable gas detector. In fact, when developing gas detectors, there are many difficulties, which the specifications listed in the sensor and the measured data values are not matched each other. It is necessary validation and calibration of specifications when sensors are used practically. In this study, the output voltages were measured by inputs of 8 kinds of standard gases into the two types of infrared gas sensor. The linear regression function derived by using least square estimation to represent the output voltages. When inverting the derived linear regression function and actually measuring its approximation equation, errors occur due to pressure of gas injection, temperature, humidity and nonlinearity of circuits. In order to reduce these errors and optimize responses of sensor"s inputs and outputs, we adjusted the slope and offset of the designed equation. Also, it is confirmed through experiment that the output according to the input is linear other than before.