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김성애,최완규,이성주,Kim, Sung-Ae,Choi, Wan-Kyoo,Lee, Sung-Joo 한국정보처리학회 2000 정보처리논문지 Vol.7 No.11
객체지향 패러다임에서 응집도가 높은 클래스들은 단 하나의 데이터 요소만이 정의되고 모든 메소드(또는 연산)들이 그 데이터 요소 상에서 수행되거나, 메소드와 데이터 요소간에 최대연결이 이루어진 클래스이다. 따라서 데이터 요소의 증가와 최대연결을 저해하는 연산들은 클래스의 응집을 저해하는 주 요인들이다. 본 연구에서는 이러한 저해요인들에 근거하여, 응집도에 관한 우리의 직관과 더욱 일치하는 측정을 할 수 있는 새로운 클래스 응집도 척도인 CM(Cohesion Metric)을 제안하였다. 본 연구에서는 응집도를 저해하는 요인의 식별을 위해 참조 그래프(reference graph)를 이용하고, 참조 그래프의 분석을 기초로 하여 클래스의 응집도를 측정하였다. 또한 제한된 CM 측정값이 응집도 척도가 만족해하는 특성들을 만족함을 보였고, 기존 응집도 척도들과의 비교평가를 통해서 CM이 기존의 척도들보다 향상된 측정을 제시함을 보였다.
김성애(Sung Ae Kim),최완규(Wan Kyoo Choi),이성주(Sung Joo Lee) 한국정보처리학회 2000 정보처리학회논문지 Vol.7 No.11
In object-oriented paradigm, highly cohesive classes define only a data factor(instance variable) whose all methods(or operations) refer to, or have the maximum connection among elements in a class. Therefore, an increase in the number of the data factors, and the operations to obstruct the maximum connection among elements in a class are the main factors to decrease the class cohesion. In this paper, we propose a new measure, called CM(Cohesion Measure), which can measure the class cohesion more consistently with our intuition on the basis of factors to decrease it. We use the reference graph in order to find the decreasing factors of the class cohesion, and measure the class cohesion on the basis of analysis of the domain reference graph. We also show that the proposed CM metrics satisfy the properties that the cohesion measures should satisfy, and that it can provide more upgraded measures than the existing measures through comparing it with the measures of existing cohesion.
김성애 ( Sung Ae Kim ),조재위 ( Jae We Cho ),이규석 ( Ky Suk Lee ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.6
Atypical Spitz`s nevus is a rare spitzoid melanocytic proliferations with an uncertain malignant potential. Atypical Spitz`s nevus have overlapping features of both Spitz nevi and spitzoid melanoma, and consequently, generate controversies with diagnosis and management. Herein, we report a case of atypical Spitz`s nevus developing on the lower right leg of a 46-year-old man. Histologically, the lesion shows numerous uniform nests of spindle cells and epithelioid cells in the dermis. The lesion had a high Ki-index, prominent cellular density, but not enough to consider a diagnosis of melanoma. The nevus was removed by total excisions. No recurrences or metastases were detected during the follow-up period of 6 months.
대상포진으로 인한 급성 표재성 피부 궤양에 대한 혈소판 풍부 혈장의 치험
김성애 ( Sung Ae Kim ),이규석 ( Kyu Suk Lee ),조재위 ( Jae We Cho ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.10
Platelet rich plasma is derived from fresh whole blood that contains a high concentration of platelets. There are many clinical reports of the effect of PRP on diverse surgical procedures, especially in the fields of orthopedic surgery and periodontic surgery. Recently, PRP has been rapidly developing as a method of wound healing and skin rejuvenation. Therefore, the aim of this study was to evaluate the effectiveness of PRP on wound healing after herpes zoster infection. We analyzed the medical records and clinical photographs of 12 patients who underwent 1∼2 PRP treatments of superficial ulcers after herpes zoster infection. The wounds that were treated by PRP healed rapidly compare to non-treated wounds. This study shows that PRP treatment is a safe and effective treatment option for skin ulcer after herpes zoster infection. (Korean J Dermatol 2011;49(10):918∼922)
김성애 ( Sung Ae Kim ),조재위 ( Jae We Cho ),이규석 ( Kyu Suk Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.8
Cancer that tends to metastasize to other internal organs also involves the skin with various clinical features. We report two cases of metastatic skin cancer that showed multiple erythematous patches on the trunk. Two patients presented with erythematous macules and a patch with telangiectasia on the trunk and chest wall. A microscopic examination of the skin biopsy specimens showed infiltration of large atypical cells with hyperchromatic nuclei and scant cytoplasm in the dermis. Using variable immunohistochemical staining, we identified the primary origin of the cancer, which was breast cancer. Usually, cutaneous metastatic carcinoma shows solitary and multiple nodules on the trunk, but there are also many unusual clinical findings. Dermatologists should pay attention to the sudden onset of symptomless erythematous patches and nodules on the trunk and conduct a skin biopsy and immunohistochemical staining. (Korean J Dermatol 2011;49(8):721∼725)
김성애 ( Sung Ae Kim ),이규석 ( Kyu Suk Lee ),조재위 ( Jae We Cho ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.2
Clinical manifestations of mycosis fungoides can vary from the classical type, which is associated with patch, plaque and tumor, to the rare atypical type which is associated with erythroderma, hypopigmentation or hyperpigmentation, and an ichthyosiform patch. A 45-year-old man presented with a 10-year history of asymptomatic erythroderma and an ichthyosiform patch on his trunk and lower extremities. On physical examination, there were asymptomatic erythematous nodules on the Rt. thigh and a palpable lymph node on the Lt. popliteal area. A histopathologic study showed infiltration of atypical cells into the upper dermis with mononuclear cell infiltration of the epidermis. On immunohistochemistry, atypical cells showed positivity for CD3, CD4, and CD8 staining, and negativity for CD20 staining. TCR-gamma rearrangement showed monoclonality. Excisional biopsy of Lt. popliteal lymph nodes showed pathology findings compatible with that of the trunk. A diagnosis of stage IVa mycosis fungoides, which is associated with erythroderma and ichthyosiform manifestations, was made. The patient was treated by a combination of PUVA and MTX chemotherapy and is still on regular follow up. (Korean J Dermatol 2011; 49(2):169~174)
김성애 ( Sung Ae Kim ),조재위 ( Jae We Cho ),이규석 ( Kyu Suk Lee ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.11
Tsutsugamushi disease is an acute febrile illness that is caused by infection with Orientia tsutsugamushi. The diagnosis is based on the patient`s history of exposure, the characteristic clinical features and serologic testing. But the diagnosis can be difficult when an eschar is overlooked or it is absent. Making the differential diagnosis with drug eruption is especially difficult when a skin rash develops with a prior medication history for fever or myalgia. We report here on 3 cases of Tsutsugamushi disease. Two of the cases were misdiagnosed as drug eruption due to medication for carbuncle or back pain. For the other case, Tsutsugamushi disease was accompanied with allergic contact dermatitis due to Rhus (lacquer tree). All the patients had fever, myalgia and an atypical skin rash that differed from that of drug eruption and allergic contact dermatitis. The detection of eschar was possible by having a clinical suspicion of Tsutsugamushi disease. Thus, we report here on three cases of Tsutsugamushi disease and these cases show the importance of taking a complete medical history and performing a thorough physical examination. (Korean J Dermatol 2010;48(11):993∼998)
필러 주입 후 발생한 안구 대상포진양 피부 괴사에 Platelet-rich Plasma (PRP) 치험
김성애 ( Sung Ae Kim ),이규석 ( Kyu Suk Lee ),조재위 ( Jae We Cho ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.1
Dermal fillers are increasingly being used for facial soft tissue augmentation. In the appropriate patient and with appropriate training, dermal fillers can temporally eliminate facial wrinkles and depressed scars. Although complications are rare, they can occur with any dermal filler. Especially, injection necrosis is a rare, but clinically important potential complication that is caused by interruption of the vascular supply to the area by compression, injury and/or obstruction of the vessel. Injection necrosis can appear to be pyoderma or a local wound infection, and so physicians should pay attention to make an accurate diagnosis. We report here on a case of a 47-year-old female who experienced sudden onset local necrosis of the glabella area after filler injection, and this was followed by a herpes zoster ophthalmicus-like necrotic lesion. We treated the necrotic lesion on the glabella area by wound dressing combined with platelet-rich plasma (PRP) treatment. (Korean J Dermatol 2010;48(1):60∼64)