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각종 폐질환에 있어서 경기관지 폐생검과 Tru - Cut Needle 을 이용한 경피적 폐생검의 비교
김광중(Kwang Joong Kim),이병철(Byung Chul Lee),유진우(Jin Woo Yu),김동윤(Dong Yun Kim),김귀완(Kwi Wan Kim),김문중(Moon Joong Kim) 대한내과학회 1989 대한내과학회지 Vol.37 No.3
N/A Lung cancer has become one of the most common cancers in Korea. Chest X-rays show solitary or diffuse infiltrative lesions but these arc not confirmed by sputum chtology and bronchoscopic exam. It is extremely necessary to establish a tissue diagnosis. Transbronchial lung biopsy and transthoracic needle lung biopsy were compared with respect to diagnostic accuracy and complications. The age distribution of the patients was from nineteen to seventy-five years and the male to female ratio was about 6:1. The diagnostic yields of the transbronchial lung biopsy and the transthoracic needle lung biopsy were 68% and 86% respectively. Common diseases were primary malignancy, pulmonary tuberculosis and interstitial fibrosis; next in order were pneumonia and lung abscess. Among the nonspecific diagnoses, 7 cases were confirmed as malignant diseases by subsequent diagnostic procedures. Complications of the transthoracic needle lung biopsy were pneumothorax in 5 cases (8%) hemothorax in one case (2%) and hemoptysis in 2 cases (4%) Complications of the transbronchil lung biopsy were hemothorax in one case (2%), and hemoptysis in two cases (4%). We think that the transthoracic needle lung biopsy represents minor, safe, accurate and simple procedure for peripheral lung lesions and the transbronchial lung biopsy is the procedure of choice for central lung lesions.
이광영(Kwang Young Lee),이병철(Byung Chul Lee),유진우(Jin Woo Yu),김민철(Min Chul Kim),김문중(Moon Joong Kim),박성광(Sung Kwang Park),강성귀(Sung Kyew Kang),최인학(In Hak Choi),최명식(Myung Sik Choi),장우현(Woo Hyun Chang) 대한내과학회 1989 대한내과학회지 Vol.37 No.2
N/A Tsutsugamushi disease is an acute febrile illness caused by Rickettsia tsutsugamushi, and is characterized by fever, skin rashes, eschar and lymphadenopathy. It is known as the endemic disease of Japan, but is also found in Southeastern Asia and the South Pacific Islands. In Korea the disease was first reported in 1986, and after that it occurred in Seoul, Kyungki-do, Kangwon-do, Choongchung-do, and Kyungsang-do provinces. We experienced 38 Tsutsugamushi disease cases occurring in the Cholabuk-do area during the period from early October till early November 1987, which were diagnosed clinically and serologically by indirect immunofluorescent antibody test with the following results. Of 38 cases, 24 were females and 14 were males, and the age distribution was from the twenties to eighties. Nearly all patients had had chances of exposure to grass fields or scrubs, and the disease occurred nearly all over the Cholabuk-do province. The most frequent symptoms were fever (100%), chill (97.4%), myalgia (92.1%), headache and backache, and the physical signs were skin rashes (94.7%), eschar (86.8%), and lymphadenopathy (55.3%). Antibody titers ranged from 1:20 to 1:2560 to Kato strain of R. tsutsugamushi, and Karp strains were cultured and isolated from the blood of 2 patients. Common laboratory findings were leukopenia (31.6%), thrombocytopenia (5.3%), elevated GOT/GPT (65.8%), alkaline phosphatase elevation (31.6%), hypoalbuminemia (18.4%), proteinuria (39.5%), hematuria (21.0 %), elevated ESR (68.8%) and positive CRP (95%). On chest film, interstitial pneumonias were noted in 10.5%, and nonspecific EKG changes including myocardial ischemia were observed in 15 patients (39.5%). All the patients showed milder clinical courses than those reported till now in Korea, and showed good response to antibiotic therapy with doxycycline or chloramphenicol.
金文重 건국대학교 1988 論文集 Vol.27 No.1
A "multinational enterprise" is " a parent company that controls a large cluster of corporations of various nationalities The corporations that make up each cluster appear resources and seem reponsive to elements of a common strategy. Size is important as well: a cluster of this sort with less than $ 100 million in sales rarely merits much attention" But to accurate this definition of the Multinational Enterprise, we need some creteria. Those are bases of structure, nationality of top management, behavior, managerial strategy, performance yardstick, a stage of growth of firms, essential factors. There are two demensions on the behavioral priciples of multinational enterprise one mangement aspects, the other economic aspects. - Mangement apects ① the theory of the change of managenent resources ② the theory of International oligopoly ③ the theory of the growth of the firms ④ the theory of product life cycle & catchiug up life aycle - Economic aspects ① the theory of different benefits and costs ② the theory of optimal tax of abroad investmenut These theories give us the poinciples of behavior for the multinational enterprise, when we enter the international market involving opportunities or risks. To have the opporturity of success in the serious international competition, we competition understand behavioral characteristics, especially fur the developing country. After all these principles give us the way to avoid the risks, to gain the successful chance of international investment.
Trichinella spiralis 感染이 마우스의 免疫反應에 미치는 影響
任善永,李黃浩,金文中,河大有 全北大學校 齒醫學硏究所 1983 전북치대논문집 Vol.1 No.1
Male, IcR mice weighing 20 to 25 gm were infected experimentally by esophageal intubation of 300 Trichinella spiralis infective muscle larvae prepared by acid-pepsin digestion of infected mice. Delayed type hypersensitivity and hemagglutinin antibody reactions to unrelated antigen, sheep red blood cell (SRBC) were measured at 37 and 83 days after infection, employing footpad and ear swelling reactions and microtitration technique. All mice were sensitized i.v. with SRBC. It was found that DTH and hemagglutinin responses to SRBC were depressed in infected mice when observed at 37 and 83 days postinfection, and degree of immunosuppression was more profound in mice observed at 83 days than in those at 37 days. The secondary cell-mediated immune response of DTH to SRBC were suppressed in Trichinella - infected mice, indicating the development of immunological memory cell is affected. In addition, immunodepression to SRBC in mice infected with T. spiralis was eliminated by pretreating infected mice by subcutaneous injection of cyclosphosphamide(100㎎/㎏) 2 days prior to infection. These results suggest that the immuno suppression in trichinellosis can be due to suppressor T cells.
박상균,이병철,이춘희,김문중,장봉열,한기옥,허기석 대한내과학회 1990 대한내과학회지 Vol.39 No.1
Thrombocytopenia with decreased megakaryocytes is a rare disorder characterized by thrombocytopenia due to a total absence or a marked reduction in the number of bone marrow megkaryocytes. We experienced a case of thrombocytopenia with decreased megakaryocytes in a 15-year-old girl, who was admitted with chief complaints of epistaxis and purpura on the lower extremities. There was a marked decrease of megakaryocytes in the marrow, and only minimal changes in other hematopoietic cell lines were seen. Follow-up studies, including bone marrow aspiration and biopsy which were performed eight months later, revealed typical features of aplastic anemia.