모야모야병에서 염기성 섬모 세포 성장 인자의 역할

김동석,최중언,김세혁,양국희,김현숙,Kim, Dong-Seok,Choi, Joong-Uhn,Kim, Se-Hyuk,Yang, Kook-Hee,Kim, Hyeun-Sook 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1

Objectives and Importance : The present study investigated the levels of basic fibroblast growth factor(bFGF) in the CSF of patients with moyamoya disease and its clinical significance. Methods : The levels of bFGF in CSF, taken from 26 hemispheres of 14 moyamoya patients and 20 patients without vascular anomaly(control group), were measured by an enzyme-linked immunosorbent assay. We analyzed the correlation between the level of bFGF and the clinical factors such as age, onset pattern, development of neovascularization, and cerebral circulation. Results : The CSF of moyamoya patients contained a high concentration of bFGF to a significant extent. The bFGF level was apparently elevated in the patients in whom neovascularization from indirect revascularization, such as modified encephalo-duro-arterio-synangiosis(EDAS) was well developed. A linear correlation between the values of bFGF and clinical progression was noted. Conclusions : The elevation of bFGF in moyamoya disease seems to be specific. Clinically, the bFGF level may be considered a useful indicator to predict the efficacy of indirect revascularization.

유방암의 Imprint 표본에서 p53 단백 발현

김동석,이은희,김기권,김미진,이수정,Kim, Dong-Sug,Lee, Eun-Hi,Kim, Ki-Kwon,Kim, Mi-Jin,Lee, Soo-Jung 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.1

This study was carried out to determine the usefulness of imprint cytology for detecting p53 protein in breast carcinoma. NCL-DO7 (Novocastra, U.K.) was used to detect p53 protein immunocytochemically. A total of 33 cases was studied, Immunostaining of imprint cytology with NCL-DO7 was positive in 64% (21/33) and showed relatively high coincident rate (80%) with immunostaining of formalin-fixed, paraffin-embedded specimen p53 protein was related to negative estrogen receptor status, but not to the nuclear grade, lymph node metastasis, or tumor size. The fact that p53 protein expression was not related to nuclear grade might be due to predominance of nuclear grade 3. It was easier to determine the nuclear grade is one of the most important prognostic factors, in imprint cytology than in tissue specimen. p53 protein tended to be stained more strongly in imprint cytology than in tissue. It is concluded that the application of imprint cytology in p53 protein detection can be performed easily, and that it may contribute to the evaluation of prognostic factors in breast carcinoma.

임펄스 UWB 네트워크에서의 일정진폭 다중접속 채널코딩

김동석(Tongsok Kim),김용철(Yong Cheol Kim) 대한전자공학회 2008 電子工學會論文誌-SC (System and control) Vol.45 No.6

이 논문은 임펄스 UWB 시스템을 위한 새로운 일정진폭 프리코딩을 제안한다. IEEE 802.15.4a 표준에 따르면 임펄스 UWB는 실내측위와 센서 데이터 전달에 사용될 수 있다. 대부분의 USN(ubiquitous sensor network)은 다중접속을 필요로 한다. 그러나 UWB 시스템은 다중접속으로 야기되는 중첩신호를 검출하는데 있어 제약성이 있다. 이를 극복하기 위하여 Wada 및 Kim의 CAMC(constant amplitude multi-code) 개념을 응용하였다. 제안하는 시스템은 체계적 일정진폭 프리코딩과 LDPC 디코딩으로 구성된다. 또한 컴퓨터 시뮬레이션을 통하여 BER 성능이 우수함을 확인하였다. In this article a novel constant amplitude precoding for impulse UWB system is proposed. According to IEEE 802.15.4a, impulse UWB can be used in indoor localization and sensor data transmission. Most USN(ubiquitous sensor networks) needs multiple access. However impulse UWB system has a limited capability to detect superpositioned signal induced by multiple access. To overcome this problem we have adopted the concept of CAMC(Constant Amplitude Multi-Code) deviced by Wada and Kim. The proposed system consists of systematic constant amplitude precoding and LDPC decoding. And this system shows a good BER performance in computer simulation.

물분무 소화설비의 적용기술과 동향

김동석,Kim, Dong-Seok 한국화재보험협회 1997 방재기술 Vol. No.

소형선박 무인기관실에 효과적인 자동소화장치 개발 연구

김동석,Kim, Dong-Seok 한국화재보험협회 2006 방재기술 Vol. No.

소개 - 로이드선급협회의 인정시험

김동석,Kim, Dong-Seok 한국화재보험협회 1994 防災와 保險 Vol.63 No.-

Box-Behnken법을 이용한 E. coli 소독에서 전기-UV-초음파 복합 공정의 최적화

김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 대한환경공학회 2011 대한환경공학회지 Vol.33 No.3

수중에서 E. coli 소독을 위한 전기-UV-초음파 복합 공정에 대해 실험계획법과 반응표면분석법(RSM)을 적용하였다. 2차반응표면 모형식을 추정할 수 있는 Box-Behnken법을 이용하여 전기-UV-초음파 복합 공정의 소독 반응에서 전기분해($X_1$), UV ($X_2$), 및 초음파 공정($X_3$)의 전력을 독립변수로 선정하여 수학적으로 모형화하였다. 소독 후 잔류 E. coli 수와 독립변수 사이의 실험에서 독립변수에 대해 다음의 모형식이 얻어졌다. 잔류 E. coli number (Ln CFU) = 23.69 - 3.75 Electrolysis - 0.67 UV - 0.26 Ultrasonic - 0.16 Electrolysis UV + 0.05 Electrolysis Ultrasonic + 0.27 $Electrolysis^2$ + 0.14 $UV^2$ - 0.01 $Ultrasonic^2$). 예측된 모형식은 실험 자료와 잘 일치하였다($R^2$ = 0.983). 2차원 등고선도와 3차원 반응표면도가 잔류 E. coli 수에 대한 최적 범위를 구하기 위하여 사용되었다. Design-Expert 소프트웨어의 '수치 최적화'를 이용하여 잔류 E. coli 수에 대한 최적 값을 찾은 결과 1.47 Ln CFU/L이었고, 최적 조건은 전기분해 6.94 W, UV 6.72 W 및 초음파 공정 14.23 W로 나타났다. 본 연구는 반응표면분석법이 복합 소독 공정에서 잔류 E. coli 수를 최소화하고 운전 조건을 최적화하기 위한 적절한 방법 중의 하나라는 것을 보여주었다. This experimental design and response surface methodology (RSM) have been applied to the investigation of the electro-UV-ultrasonic complex process for the disinfection of E. coli in the water. The disinfection reactions of electro-UV-ultrasonic process were mathematically described as a function of parameters power of electrolysis ($X_1$), UV ($X_2$), and ultrasonic process ($X_3$) being modeled by use of the Box-Behnken technique, which was used for fitting 2nd order response surface model. The application of RSM yielded the following regression equation, which is empirical relationship between the residual E. coli number (Ln CFU) in water and test variables in coded unit: residual E. coli number (Ln CFU) = 23.69 - 3.75 Electrolysis - 0.67 UV - 0.26 Ultrasonic - 0.16 Electrolysis UV + 0.05 Electrolysis Ultrasonic + 0.27 $Electrolysis^2$ + 0.14 $UV^2$ - 0.01 $Ultrasonic^2$). The model predictions agreed well with the experimentally observed result ($R^2$ = 0.983). Graphical 2D contour and 3D response surface plots were used to locate the optimum range. The estimated ridge of maximum response and optimal conditions for residual E. coli number (Ln CFU) using 'numerical optimization' of Design-Expert software were 1.47 Ln CFU/L and 6.94 W of electrolysis, 6.72 W of UV and 14.23 W of ultrasonic process. This study clearly showed that response surface methodology was one of the suitable methods to optimize the operating conditions and minimize the residual E. coli number of the complex disinfection.

스펀지에 고정한 광촉매를 이용한 안료의 탈색

김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 한국환경보건학회 2005 한국환경보건학회지 Vol.31 No.5

The photocatalytic decolorization of Reactive Red 2B(RR2B) was studied using immobilized photocatalyst/UV System. Two pairs of 20 W UV-B and UV-C lamps were employed as the light source. Immobilization of $TiO_2$ was carried out using sponge (as the photocatalyst body) and silicone sealant(as the binder). The effects of parameters such as the thickness, pore size of sponge photocatalyst and attached material on the reactor bottom were investigated. The results showed that the optimum thickness of sponge photocatalyst was 1 cm. Decolorization of reactor which had the bottom coated $TiO_2$ was higher than that of reactor attached aluminum plate. Decolorization of photocatalyst with large pore size(mean pore size, 3.8 mm) was higher than that of the small(mean pore size, 1.75 mm). Initial decolorization of RR2B could be descrived using the Langmuir-Hinshelwood(L-H) model and gave constant values of $0.55mg/l{\cdot}min(k)\;and\;2.65{\times}10^{-2}l/mg(K)$, respectively.

서로 다른 산포를 허용하는 이변량 영과잉 음이항 회귀모형

김동석,정슬기,이동희,Kim, Dong-Seok,Jeong, Seul-Gi,Lee, Dong-Hee 한국통계학회 2011 Communications for statistical applications and me Vol.18 No.5

본 연구에서는 두 반응 변수에 서로 다른 산포를 허용하는 새로운 이변량 영과잉 음이항 회귀모형을 제안하고, Deb과 Trivedi (1997)에 나타난 헬스케어 자료를 이용하여 두 반응변수가 갖는 서로 다른 산포도를 무시한 Wang (2003)이 제안한 이변량 영과잉 음이항 회귀모형과의 효율성을 로그우도와 AIC의 관점에서 비교 하였다. 모형적합결과, 본 연구에서 제안한 모형이 모형선택기준 관점에서 기존모형에 비하여 월등히 우수한 결과를 보여주었다. We propose a new bivariate zero-inflated negative binomial regression model to allow heterogeneous dispersions. To show the performance of our proposed model, Health Care data in Deb and Trivedi (1997) are used to compare it with the other bivariate zero-inflated negative binomial model proposed by Wang (2003) that has a common dispersion between the two response variables. This empirical study shows better results from the views of log-likelihood and AIC.

전기-펜톤 공정에 의한 페놀의 전기화학적 분해

김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 한국환경보건학회 2009 한국환경보건학회지 Vol.35 No.3

Oxidation of phenol in aqueous media by electro-Fenton process using Ru-Sn-Sb/graphite electrode has been studied. Hydrogen peroxide was electrically generated by reaction of dissolved oxygen in acidic solutions containing supporting electrolyte and $Fe^{2+}$ was added in aqueous media. Phenol degradation experiments were performed in the presence of electrolyte media at pH 3. Effect of operating parameters such as current, electrolyte type (NaCl, KCl and $Na_2SO_4$) and concentration, $Fe^{2+}$ concentration, air flow rate and phenol concentration were investigated to find the best experimental conditions for achieving overall phenol removal. Results showed that current of 2 A, NaCl electrolyte concentration of 2g/l, 0.5M concentration of $Fe^{2+}$, air flow rate of 1l/min were the best conditions for mineralization of the phenol by electro-Fenton.