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김나영(Na-Young Kim),조아라(A-Ra Cho),정수지(Su-Ji Jung),김경희(Kyoung-Hee Kim),이효정(Hyo-Jeong Lee),이슬(Seul Lee),육홍선(Hong-Sun Yook) 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.1
본 연구에서는 백년초 분말의 1, 3, 5% 첨가가 항산화성 및 컵케이크의 품질과 관능적 기호도, 저장성에 어떠한 영향을 주는지 확인하여 제품화의 최적조건 및 기능성 식품 소재로서의 이용가능성을 조사하였다. 백년초 분말의 각 농도에 대한 전자공여능 실험결과 백년초 분말의 농도가 증가함에 따라 항산화 활성이 증가하였다. 백년초 분말과 백년초 분말을 첨가한 컵케이크에서의 미생물 분석 결과 효모, 곰팡이, 대장균군은 검출되지 않았고 일반세균은 백년초 분말에서 4.41 log CFU/g로 나타났고 컵케이크에서는 검출한계(10² CFU/g) 이하로 나타났다. 컵케이크의 수분함량은 백년초 분말을 첨가한 구가 첨가하지 않은 구보다 높았으나 유의적인 차이는 없었다(p<0.05). 색도는 첨가량이 증가할수록 crust와 crumb에서 명도와 황색도가 감소하고 적색도는 증가하였다. 물성은 백년초의 첨가 및 저장기간의 증가에 따라 견고성(hardness), 검성(gumminess), 씹힘성(chewiness)이 증가하였고 응집성(cohesiveness), 탄력성(springiness)은 감소하였다. 관능검사 결과 대조군 및 1% 백년초 분말 첨가 컵케이크가 색, 향, 맛, 조직감, 전체적인 기호도면에서 높은 점수를 받았다. 이러한 결과로 볼 때 백년초 분말을 컵케이크에 첨가하였을 때 항산화효과를 기대할 수 있으나 저장성에는 큰 영향을 미치지 않을 것으로 사료되었고, 컵케이크의 품질 및 관능특성, 기능성을 고려할 때 1% 첨가구가 최적조건일 것으로 판단되었다. Antioxidative activity and functional properties of the powder obtained from ground Opuntia ficus?indica var. saboten fruit were studied. Cupcakes containing 1, 3, and 5% (w/w) of O. ficus?indica var. saboten powders were prepared and evaluated for their sensory property, textural quality, and shelf?life. The antioxidative activity, measured by DPPH radical scavenging activity of O. ficus?indica var. saboten powder, increased as the concentrations of O. ficus?indica var. saboten powder increased. No coliform bacteria, yeasts, and molds were detected in either the O. ficus?indica var. saboten powder or in the cupcakes. However, total aerobic bacteria counts were 4.41 log CFU/g in the O. ficus?indica var. saboten powder and were a negligible level (<10² CFU/g) in the cupcakes. Moisture content of the cupcakes was not significantly different in all samples. Lightness (L) and yellowness (b) of cupcake color decreased as the concentration of O. ficus?indicavar. saboten powder increased, whereas the redness (a) increased. Increasing the concentration of O. ficus?indica var. saboten powder, the mechanical characteristics of the cupcakes, such as hardness, gumminess, and chewiness, while decreasing cohesiveness and springiness. The sensory properties, such as color, flavor, taste, texture, and overall acceptability, of the cupcakes containing the 1% O. ficus?indica var. saboten powder were superior to the control sample. The results exhibited that the adding the O. ficus?indica var. saboten powder into the cupcakes increased antioxidant activity and showed no effect on shelf?life of the cupcakes. The highest quality improvement was obtained by incorporating the 1% (w/w) of O. ficus?indica var. saboten powder into the cupcake formula.
${\ll}$교주부인양방(校注婦人良方)${\gg}$에 수재된 의무기록 의안(醫案)에 관한 연구
오창영,김나영,박영수,김병회,조호근,김중오,김동일,Oh, Chang-Young,Kim, Ra-Young,Park, Young-Soo,Kim, Byoung-Hoe,Joh, Ho-Geun,Kim, Joong-Oh,Kim, Dong-Il 대한한방부인과학회 2006 大韓韓方婦人科學會誌 Vol.19 No.2
Background : Medical records are documents in files which consist of all diagnostic studies and medical treatments patients had received while they were hospitalized or treated as outpatients. A doctor or medical team can use medical records as a data for diagnosis, treatment, and education. In traditional eastern asian medicine, medical reports have different forms and contents. The most important thing in medical reports of traditional eastern asian medicine was how to express practitioner's medical ideas. So it has a weak point, for example, it has poor information about patient and clinical process, which make some trouble to understand it. Methods and Results : We studied medical records in Gyojubuin-yangbang, a commentary book of Chen-zi-ming's Obstetrics and Gynecology textbook done by Xue-ji in Ming dynasty, China. This book consists of 10 parts; treatment of menstruation disorders and leukorrhea, general gynecology, treatment of infertility, education for fetus, diagnosis of fetus and gravida, treatment of general and obstetrical disease in gravida, care for delivery, postpartum care and treatment, and treatment of mass and inflammation. It has 546 medical records about women's disease that commonly believed as Xue-ji's case reports. They are all review articles and made during about 23 years from A.D 1523 to 1546. Most patients of Xue-ji's case reports were common people, this fact is different from that of case reports in Chen-zi-ming's Obstetrics and Gynecology textbook. Conclusion : Xue-ji was a very famous Ob&Gy doctor who was from Suzhou Jingsu province in China. He was born in A.D 1468, died in A.D 1588. He emphasize emotional factors in pathology and to tonify spleen and kidney. We think Xue-ji's medical records are good references for us to treat psychosomatic Ob&Gy disease and chronic women's disease.
다발성 전이를 동반한 후복막강 악성 혈관주위상피모양세포종양
오혜원 ( Hye Won Oh ),김태효 ( Tae Hyo Kim ),차라리 ( Ra Ri Cha ),김나영 ( Na Young Kim ),김현진 ( Hyun Jin Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ),이정희 ( Jeong Hee Lee ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.5
Perivascular epithelioid cell tumors (PEComas) are unusual mesenchymal neoplasms composed of histologically and immunohistochemically distinct perivascular epithelioid cells (PECs). Although PEComas have the potential to behave in a malignant fashion, malignant PEComas arising from the retroperitoneum are extremely rare. A 68-year-old woman presented with a painful palpable mass in her left upper abdomen. Computed tomography of the abdomen showed a 9 cm sized heterogeneous mass in left para-aortic space and multiple hypervascular nodules in the liver. 18F-fludeoxyglucose-PET/CT showed multifocal hypermetabolic lesions in retroperitoneum, liver, and skeletal bones. Percutaneous needle biopsies were done on the retroperitoneal and hepatic mass. Both specimens were positive for human melanoma black-45 (HMB-45) on histological and immunohistochemical staining which was compatible with PEComas. Herein, we report a rare case of retroperitoneal PEComa with multiple metastases involving liver and bone at initial diagnosis that exhibited aggressive behavior and resulted in a devastating prognosis. (Korean J Gastroenterol 2014,64:302-306)
세포대사 기능 분석을 위한 광학센서 기반 용존산소와 pH 측정 시스템의 제작 및 특성 분석
장지운 ( Ji Woon Jang ),황인숙 ( In Sook Hwang ),이종목 ( Jong Mok Lee ),이선민 ( Sun Min Lee ),강소라 ( So Ra Kang ),김영미 ( Young Mi Kim ),김나영 ( Na Young Kim ) 한국센서학회 2016 센서학회지 Vol.25 No.1
This study evaluates the performance of an optical sensor and measurement system (CMA-24) which can analyze the fluctuation of dissolved oxygen and pH simultaneously. In the optical sensor system, the fluorescent materials, Rudpp and HPTS which are sensitive to dissolved oxygen and pH, respectively, are coated on the bottom of a 24-well -plate by the sol-gel technology. The detection times of the emission light of the oxygen sensor were 4,186±13.90 μs and 4,452±36.68 μs for the dissolved oxygen of 17% O2 and 7.6% O2, respectively. On the other hand, the detection times of the pH sensor were 6,699.43 ± 14.64 μs, 6,722.24±6.21 μs, and 6,748.52 ±2.63 μs using pH 6, 7, and 8, respectively. When we determined cellular respiration levels of C2C12 myocytes with CMA-24, O2/ pH measurement system, the ratio of the uncoupled to coupled OCR (oxygen consumption rate) was 1.41. The results mean that this CMA-24 system shows almost the same sensitiveness as the commercial system.