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이재영 ( Chae Yong Yi ),나경준 ( Gyoung Jun Na ),백현철 ( Hyun Choul Baek ),김정훈 ( Jeong Hoon Kim ),배상훈 ( Sang Hun Bae ),김동현 ( Dong Hyun Kim ),제인수 ( In Soo Je ),권병표 ( Byoung Pyo Kwon ) 대한소화기학회 2008 대한소화기학회지 Vol.51 No.1
Although most of pseudocysts as one of complications of pancreatitis occur primarily within the pancreas, the extrapancreatic locations of pseudocysts, especially in the liver, are rare events. With advanced technology of imaging studies including abdominal computed tomography, ultrasonography, and magnetic resonance imaging, their frequency seems to be increasing. We report here a case of left intrahepatic pancreatic pseudocyst following acute pancreatitis. Percutaneous puncture revealed a high level of amylase and lipase in the collection, confirming the diagnosis of intrahepatic pseudocyst. Symptomatic intrahepatic pseudocysts can be managed surgically, transcutaneously or endoscopically, and asymptomatic intrahepatic pseudocysts can be treated conservatively. We report this case with a review of literature. (Korean J Gastroenterol 2008;51:56-59)
급성 전골수구성 백혈병(M3) 환자에서 플루코나졸로 치료한 간 칸디다증 1예 : Successful treatment with fluconazole
원종진,권병표,김성현,이혁,권혁찬,김재석,김효진 대한내과학회 2004 대한내과학회지 Vol.66 No.5
일반적으로 대부분의 임상의들은 혈액학적 악성질환 환자들에게 항암화학요법 이후 간 칸디다증이 진단되며 amphotericin B를 우선 정주 한다. 그러나 본 증례에서처럼 혈액진 균배양검사 결과상에서 배양이 되지 않을 경우 amphotericin B의 정주 후에도 임상소견 및 거사실 소견의 호전이 없다면 fluconazole의 정주로 치료 전략을 바꾸는 것이 바람직 하다고 생각한다. The frequency of invasive fungal infections has increased during the period of chemotherapy. Fungal infections are an increasing cause of morbidity and mortality in patients with hematological malignancies. The most common organism are Candida albicans. This report describes our experience in a 28-year-old woman who developed symptoms of hepatic candidiasis which were confirmed with liver biopsy after remission induction chemotherapy for acute myeloid leukemia. In our case, the patient did not improve clinically despite administration of 610 mg amphotericin B. Severe leukocytosis, increasing alkaline phosphatase and clinical deterioration developed rapidly, and then we switched to flconazole, taking into consideration successful fluconazole treatment of patients with chronic disseminated candidiasis and acute hepatic candidiasis. She remains in clinically and radiological improving at the time of this report.
p-ANNA 강양성을 보인 제1형 자가면역성 간염 1예
정동성,정제혁,권병표,안상준,장진석,한상영,김경희 대한내과학회 2004 대한내과학회지 Vol.66 No.3
38세 여자에서 강양성의 p-ANNA 수치를 보여 ERCP로 원발성 경화성 담관염을 배제 후 제1형 자가면역성 간염으로 진단을 하였다. p-ANNA와 자가면역성 간염의 관계에 대해서는 추후 연구가 필요할 것으로 보인다. Autoimmune hepatitis (AIH) is an undissolved inflammatory process of the liver characterized by the periportal hepatitis on histological examination and serum autoantibody. AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. Perinuclear-Antineutrophil nuclear antibody (p-ANNA) are detected in up 세 88% of patient with primary sclerosing cholangitis (PSC) and presence of p-ANNA in PSC makes them a reasonable diagnostic maker in conjuction with standard diagnostic test. But p-ANNA in AIH is rare and it's role remain unclear. We report the first case of 39 year-old-female patient with AIH type-1 with p-ANNA strong positivity.