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정상피부에 기거하는 Propionibacterium acnes의 혈청형 분포
고성백,최철순,양용태 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.2
정상 피부에 기거하는 Propionibacterium acnes의 형별분포를 조사하기 위하여 P. acnes를 피부(이마)에서 분리하여 동일 개체내의 형별 분포를 조사하였으며, 188명의 건강한 피부에서 대표주를 선발하여 혈청형을 균체 응집 반응에 의하여 실시하였다. 얻어진 성적을 종합하면 다음과 같다. 1. 정상 피부에 기거하는 P. acnes의 형병 분포에 따라 개체는 type Ⅰ의 분포(74.1±7.2%)가 우세한군, type Ⅱ의 분포(49.4±1-.2%)가 우세하나 미분류 주의 분포(34.1±13.7%)와 유의성 차이가 없는 군, 그리고 특이 응집 항원이 없는 균주의 분포(62.3±16.5%) 가 우세한 군으로 분류되었다. 2. P. acnes의 형별 분포에 따라 3개군으로 분류되었으나 양형은 공존하였다. 3. P. acnes의 형별 분포에 혈청내의 형특이항체값간에는 상관성이 없었다. 4. 피부 1㎠의 면적에서 유래된 배양의 최종 집락을 개체별 대표주로 선발한 188주를 형별 동정한 결과 type Ⅰ 119주(63.3%), type Ⅱ 36주(17.6%), 미분류균주 43주(19.2%)이었다. 이상의 성적은 P. acnes type Ⅰ이 type Ⅱ에 비하여 정상 피부에 더 많은 분포로 기거하지만 양형이 공존한다는 것을 의미한다. On the skin, the resident flora may play an important role for the prevention of both colonization by pathogenic bacteria and possible diseases through their bacterial interference. The common resident flora of human skin are anaerobic diphtheroid bacilli such as Propionibacterium acnes(Corynebacterium parvum), P. granulosum and P. avidum. Of these species, P. acnes is the predominant resident flora and plays a major role for the enhancement of host's cell-mediated immunity. Particularly, the "Corynebacteriuni parvum vaccines" are often applied as bacterial adjuvant in tumorimmunotherapy. At the present time, the strains of P. acnes are devided into two types, type Ⅰ and type Ⅱ, on the basis of type specific cell wall antigens, and the"C. parvum vaccine" strains are similar to type Ⅱ in their morphology and biological properties. This finding suggests that the higher frequency of presence of type Ⅱ of P. acnes over type Ⅰ on the skin may be more beneficial for the enhancement of the cellular immunity and may result in augmenting the host immunity, against tumor development. However, the distribution of the types of P. acnes on the human skin has not been clarified. In this study, an attempt was made to survey. the distribution of the types of P. acnes in the same individuals and the types of 188 isolates from normal human skin were studied by agglutination test. Of 188 isolates, 119 strains(63.3%) belonged to type Ⅰ, 36 strains (19.2%) were type Ⅱ and 43 strains(17.6%) were not typable. Individuals may be devided into three groups according to the distribution of types; i.e., group Ⅰ was predominat with P. acnes type Ⅰ, group Ⅱ was predominant with P. acnes type Ⅱ and group Ⅲ was predominant with not-agglutinating propionibaceria to both type speiefic sera.
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도파민 수송체-cDNA 유전자의 분리와 구조적 특성에 관한 연구
고성백,이용성,고재경 한양대학교 의과대학 1942 한양의대 학술지 Vol.14 No.2
To characterize the structural features of dopamine transporter, it was tried to delete C-or N-terminal region from dopamine transporter cDNA and their effects on transporting activity were evaluated. A PCR reaction was carried out using two primers of which nucleotide sequences are identical to the 4th and 7th transmembrane domain of a known dopamine transporter cDNA. The whole dopamine transporter cDNA was isolated from bovine brain cDNA library using the PCR product of 360 base pair length as a DNA probe. The length of whole dopamine transporter cDNA was 2630 bases with 1854 bases for protein coding region. The pRc/CMV-ND, in which the region from N-terminal just prior to 1st transmembrane domain was deleted, and pRc/CMV-CD, in which the region from C-terminal to just after the 12th transmembrane domain was deleted, were constructed usine PCR and were transfected into mammalian cells. Neither of them showed dopamine transporting activity and it was suggested that the C-terminal and N-terminal regions are essential to maintain transporting activity in dopamine transporter.
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H.264/AVC에서 화면 간 예측 모드의 압축 성능 향상을 위한 적응적인 계수 탐색 방법
백승진(Seung-Jin Baek),박천수(Chun-Su Park),고성제(Sung-Jea Ko) 대한전자공학회 2009 電子工學會論文誌-SP (Signal processing) Vol.46 No.3
H.264/AVC는 높은 압축 성능을 보이는 현존하는 가장 우수한 비디호 부호화 표준이다. H.264/AVC는 양자화된 변환 계수를 부호화하기 위해 지그재그 탐색 방법을 채택하고 있다. 하지만 이 방법은 모든 블록의 양자화된 변환 계수를 블록의 특성을 고려하지 않고 동일한 순서로 탐색하기 때문에 효과적이지 못하다. 따라서 본 논문에서는 H.264/AVC의 화면 간 예측에서 압축 효율을 증가시키기 위한 적응적인 계수 탐색 방법을 제안한다. 제안하는 방법에서는, 이전 블록들의 정보를 기반으로 각 화면 간 예측 모드의 계수 탐색 순서를 조절한다. 실험 결과는 제안하는 적응적인 계수 탐색 방법은 고화질의 HD 영상에서 2.29%의 압축 효율 향상을 보여준다. H.264/AVC is the state-of-the-art video compression standard which achieves high coding efficiency compared with the previous standards. H.264/AVC adopts zig-zag scanning in order to encode quantized transform coefficients in a block. However, its performance is not satisfactory because all blocks are scanned in the fixed order without considering the characteristics of blocks. This paper presents an adaptive coefficient scanning method for improving inter coding efficiency in H.264/AVC. In the proposed method, the coefficient scanning order for each prediction mode is adaptively controlled based on the information of previously-coded blocks. The experimental results show that the proposed coefficient scanning method improves the coding efficiency about 2.29% for high-quality HD sequences.
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김태숙,문영삼,고성백,노일현 대한마취과학회 1980 Korean Journal of Anesthesiology Vol.13 No.3
Postoperative total blindness was seen in a 48 year old male who had a laparotomy for traumatic perforation of intestine. General inhalation anesthesia of ether-oxygen-mask with semiclosed system was applied after initial ketamine administration. This unhappy ocular complication could be occur secondary to excessive prolonged external compression to eyeballs with mask or/and prolonged postoperative hypotension.
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이현섭,윤영준,최병조,고성백 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.1
The authors analyzed statistically 4436 cases of emergency anesthesia which were performed at the Department of Anesthesiology, Han-Gang Sung Shim Hospital from Dec. 1971 to Dec. 1976 according to sex, age, department, physical status, anesthetic rnethod, anesthetic agent, anesthetic duration, and mortality. The results were as follows: 1) About forty-five percent of all anesthetic patients were emergency cases. 2) About sixty-three percent of all emergency patients were in the 21 40 age group. 3) The most common disease was appendicitis (996 cases). 4) Halothane was the most commonly used anesthetic agent. . 5) Closed or semiclosed circuit absorption anesthesia with endotracheal intubation was mainly employed. 6) Hypotension developed in twelve percent of all emergency anesthesia cases and whole blood was transfused in 1128 cases. 7) Intraoperative and postoperative death occurred in 233 cases, mainly with neurosurgical operations.
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