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강태건,조성구 한국경영과학회 1996 韓國經營科學會誌 Vol.21 No.2
The personality types developed by Gustav jung are frequently used to identify people's decision-making style, especially to determine which functions are dominant ones in the perception and the processing of information. In this paper, the Jungian typology is utilized to investigate if there are any systematic relations between an individual's personality type and her/his attitude toward risk. For this purpose, an experiment was conducted where 99 subjects, mostly students, participated in a computer-simulated horse racing game. Each subject's risk-seeking propensity was measured by the winning chance of the selected horse and the amount of stakes. The results of the experiment show that a decision-maker who is extrovert(E) in attitude and intuitive(N) in perception of information is more likely to be risk prone than the introvert(I) and sensing(S) type. Feeling(F) function in information processing seems to induce more risk seeking attitude than thinking(T) function, but the statistical significance could not be found from the data, for this statement.
강태건,조성구 동국대학교 산업기술환경대학원 1998 산업기술논총 Vol.4 No.-
Lottery game is one of the most frequently used tools to study people's risk attitude. However, even if two different decision problems can be represented by the same lottery, decision maker's risk attitude may not be the same due to the different decision contexts. This paper presents the results of an experiment designed to study the contextual influence of decision problems on the decision maker's risk attitude. In the experiment, some realistic decision problems, which can be represented by similar lottery games but are contextually different, are formulated and presented to the subjects using a questionnaire form. The results show that people's risk attitude is significantly dependent on decision context and that in some situations the revealed attitudes disagree with the results of the previous researches. It is also noted that for the experimental studies concerning risk attitude to produce more meaningful results, it would be better to relax the strict definition of risk neutral attitude, i.e., expected value '=' certainty equivalent'.
강태건,박효진,문지현,이준형,하상준 대한면역학회 2021 Immune Network Vol.21 No.3
Chemokines are key factors that influence the migration and maintenance of relevant immune cells into an infected tissue or a tumor microenvironment. Therefore, it is believed that the controlled administration of chemokines in the tumor microenvironment may be an effective immunotherapy against cancer. Previous studies have shown that CCL3, also known as macrophage inflammatory protein 1-alpha, facilitates the recruitment of dendritic cells (DCs) for the presentation of tumor Ags and promotes T cell activation. Here, we investigated the role of CCL3 in regulating the tumor microenvironment using a syngeneic mouse tumor model. We observed that MC38 tumors overexpressing CCL3 (CCL3-OE) showed rapid regression compared with the wild type MC38 tumors. Additionally, these CCL3-OE tumors showed an increase in the proliferative and functional tumor-infiltrating T cells. Furthermore, PD-1 immune checkpoint blockade accelerated tumor regression in the CCL3-OE tumor microenvironment. Next, we generated a modified CCL3 protein for pre-clinical use by fusing recombinant CCL3 (rCCL3) with a non-cytolytic hybrid Fc (HyFc). Administering a controlled dose of rCCL3-HyFc via subcutaneous injections near tumors was effective in tumor regression and improved survival along with activated myeloid cells and augmented T cell responses. Furthermore, combination therapy of rCCL3-HyFc with PD-1 blockade exhibited prominent effect to tumor regression. Collectively, our findings demonstrate that appropriate concentrations of CCL3 in the tumor microenvironment would be an effective adjuvant to promote anti-tumor immune responses, and suggest that administering a long-lasting form of CCL3 in combination with PD-1 blockers can have clinical applications in cancer immunotherapy.
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안춘수,강태건,정상윤,홍성일 한국산업경영시스템학회 1997 한국산업경영시스템학회지 Vol.20 No.44
In this paper, we propose a simple and relatively efficient heuristic method to determine job sequencing in the flow-shop considering multiple criteria such as processing time, due date and cost. The proposed method is applicable to the flow- shop where the jobs are released simultaneously and their processing sequence is predetermined and not changed until the whole jobs are processed. To develop this method, we mixed and modified some well-known multi-attribute decision heuristics such as the simple linear weighting scheme, the lexicographic rule and the 'elimination by aspect' rule. Some computer simulations were conducted to test the efficiency of the proposed method and it has been compared with the SWPT (Shortest Working Processing Time) rule and EDD (Earliest Due Date) rule. The results show that our method is as effective as the traditional ones in terms of mean flow time, tardiness, makespan, cycle time, machine utilization, etc., and proved to be much simpler and more flexible to be used in real situations.
김성민,김성재,강태건 대한의용생체공학회 2003 의공학회지 Vol.24 No.1
본 연구에서는 경량휠체어 탑승자의 차량 전방충돌시 안전성 평가를 위하여 동적 슬래드 충격실험을 하였다. 실험은 총 6회 시행하였으며 충격속도는 20g/48 $\pm$2km/h 였고, Hybrid III 50%ile 성인남자 인체모형을 사용하여 두부손상기준(Head Injury Criteria), 목의 굴전모멘트, 축 인장력, 전단력, 흉부 가속도. 두부, 휠체어, 무릎의 전방 쏠림량을 측정하였으며 미국자동차학회 규격인 SAE J2249에서 제안한 동작기준 (Motion Criteria)과 미국 제너럴모터스사의 자체기준(GM-IARV)인 복합상해기준(Combined Injury Criteria)을 이용하여 안전성평가를 하였다. 실험결과는 경량 휠체어 탑승자의 전방 충돌 시 최대 상해치를 100%로 봤을 때 휠체어와 탑승자 거동의 위험도지수 MC는 52%, 탑승자의 상체 위험도지수 CIC는 60.1% 였다. In this study, for a safetv assessment of light weight wheelchair occupant in frontal crash, we tested a dynamic sled impact test. we carried out total 6 times test and impact speed was 20g/48 km/h. By using Hybrid III 50%ile male dummy, head injury criteria(HIC), neck flexion moment, neck axial tension force, neck shear force. chest acceleration, head, wheelchair and knee excursion were measured, we evaluated light weight wheelchair occupant safety by motion criteria(MC) which proposed in SAE J2249 and combined injury criteria(CIC) which is a voluntary standard(GM-IARV) of General Motors Co.. when we assumed that the maximum injury value in frontal crash was 100%, the result of motion criteria(MC) of wheelchair occupant was 52%, occupant upper body injury index(CIC) was 60.1%.