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김영건(Young Kun Kim),이복희(Bok Hee Lee),박헌진(Hun Jin Park),이헌영(Heon Young Lee),안정기(Jeong Ki Ahn),강원권(Won Kwon Dang) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
N/A The clinical, laboratory and pathological features were evaluated in 44 patients with fatty liver, those were proved by nedle biopsy. The following results were obtained. 1) The mean age of the patients was 40.2 ± 11.8 years old, and the most prevalent age group was 4th decade (40.9%). The male and female ratio was 3.4:l. 2) Suspected etiologies were obestity (61.4%), alcohol (18.2%), crytogenic (13.6%), Diabetes Mellitus (6.8%), and prednisolon (2.3%), in order of frequency. 3) Clinical symptoms were asymptomatic (50%), fatigue and/or weakness (43%) and anorexia (16 %) etc. 4) Degrees of fatty infiltration on biopsy specimens revealed mild (18.2%) moderate (45.5%) and severe (36.4%). 5) Degrees of ultrasonographic findings (20 cases) resemble those degree of biopsy findings and positive rate was 80%. 6) Liver scan showed mottlings in 44% of patients and 28% of patients had no abnormal findings. 7) HBsAb positive cases were 61.4%, and no HBV markers found in 31.8% of the patients. 8) Diagnoses without liver biopsy were NANB hepatitis about half of the patients and only 20% of cases were suspected as fatty liver. 9) At the time of diagnosis, hypertriglyceridemia revealed at rate of 75% (30/40 cases) and the differences of the levels of serum TG, ALT and AST according to the degrees of fatty infiltration were not presented significantly. 10) The differences of the TG, ALT and AST levels between before and after treatment were noted significantly. 11) The significant relationships between degrees of fatty liver and degrees of obesity were observed (Grade I and II: p<0.05, I and III: p<0.01).