장액성 삼출액의 도말 표본에서 반응성 중피세포와 샘암종 세포의 감별에 중피세포 표지자의 유용성

강미선,최수임,Kang, Mi-Sun,Choi, Soo-Im 대한세포병리학회 2006 대한세포병리학회지 Vol.17 No.2

Evaluation of serous effusions can include immunocytochemical stains that differentiate reactive mesothelial cell from adenocarcinoma cell. Among several positive mesothelial cell markers, we used desmin, CK5/6, WT1 and calretinin all known to have high sensitivity and specificity as selective mesothelial cell markers. We studied smears obtained with cytospin from 15 malignant and eight benign effusions. The mesothelial cells were positively stained by desmin, CK5/6, WT1 and calretinin in 60.9%, 29.1%, 26.7% and 56.5%, respectively among 8 benign and 15 malignant effusions; the adenocarcinoma cells were positively stained 6.7%, 13.3%, 1.0% and 0.0%, respectively among 15 malignant effusions. The percentage of positively stained mesothelial cells were somewhat lower for all antibodies compared to the results of previous studies. This was likely due to the differences in preparation methods and fixatives among studies. In conclusion, the use of desmin and calretinin were more valuable than CK5/6 and WT1 for distinguishing between reactive mesothelial cell and adenocarcinoma cells in serous effusion; however, choice of the proper preparation methods and fixatives are also important

소아 만성 재발성 호흡기 증상에 대한 고찰

강미선,김장현,Kang, Mi-Sun,Kim, Jang-Hyun 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.2

Respiratory tract symptoms such as cough, wheeze, and strider may occur frequently or persist for long periods in a substantial number of children, others may have persistent or recurring lung infiltrates with or without symptoms. It is important to study on clinical significance of this symptoms for avoiding unnecessary test or treatment. Chronic or Recurrent Respiratory Symptoms are similar to cold(感冒) and cough(咳嗽) in Oriental Medicine. Diagnostic criteria is followed : in case of children less than three years old, upper respiratory infections are more than seven per year or lower respiratory infections are more than three ; in case of children three to five years old, upper respiratory infections are more than six per year or lower respiratory infections are more than two ; in case of children six to twelve years old, upper respiratory infections are more than five per year or lower respiratory infections are more than two. In oriental medical treatment is classified into the treatment of internal use, external use, internal and external use, acupuncture, cupping therapy, and combination treatment of chinese and western medicine.

위상차 현미경 영상 내 푸리에 묘사자를 이용한 암세포 형태별 분류

강미선,이정엄,김혜련,김명희,Kang, Mi-Sun,Lee, Jeong-Eom,Kim, Hye-Ryun,Kim, Myoung-Hee 대한의용생체공학회 2012 의공학회지 Vol.33 No.4

Tumor cell morphology is closely related to its migratory behaviors. An active tumor cell has a highly irregular shape, whereas a spherical cell is inactive. Thus, quantitative analysis of cell features is crucial to determine tumor malignancy or to test the efficacy of anticancer treatment. We use 3D time-lapse phase-contrast microscopy to analyze single cell morphology because it enables to observe long-term activity of living cells without photobleaching and phototoxicity, which is common in other fluorescence-labeled microscopy. Despite this advantage, there are image-level drawbacks to phase-contrast microscopy, such as local light effect and contrast interference ring. Therefore, we first corrected for non-uniform illumination artifacts and then we use intensity distribution information to detect cell boundary. In phase contrast microscopy image, cell is normally appeared as dark region surrounded by bright halo ring. Due to halo artifact is minimal around the cell body and has non-symmetric diffusion pattern, we calculate cross sectional plane which intersects center of each cell and orthogonal to first principal axis. Then, we extract dark cell region by analyzing intensity profile curve considering local bright peak as halo area. Finally, we calculated the Fourier descriptor that morphological characteristics of cell to classify tumor cells into active and inactive groups. We validated classification accuracy by comparing our findings with manually obtained results.

모(某) 한방병원(韓方病院) 소아과(小兒科)에 내원(來院)한 영아기(?兒期) 환아(患兒)에 대한 임상적(臨床的) 고찰(考察)

강미선,김장현,Kang, Mi-Sun,Kim, Jang-Hyun 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.2

The Purpose of this study was to investigate infancy patients who had visited Oriental Medicine Hospital, and so to consider a counterplan by oriental medicine. The study was composed of 101 new infancy patients who had visited Dongguk Kyeongju Oriental Medicine Hospital during 1 year from January 2001 to December 2001. The results were as follows : 1. Male children are 65(64.3%), female children are 36(35.6%), male to female ratio is 1.8: 1. 2. In age distribution, 1 month 5.9% ; 2 month 10.9%, 3 month 4.0%, 4 month 11.9%, 5 month 5.9%, 6 month 9.9%, 7 month 10.9%, 8 month 10.9%, 9 month 10.9%, 10 month 14.8%, 11 month 4.0%. 3. According to systematic division of the chief complaint, respiratory diseases are 37.6%, digestive diseases are 25.7%, nervous diseases are 21.8%, urogenital diseases are 1.0%, musculoskeletal diseases are 1.0%, dermatologic diseases are 7.9%, infirmity diseases are 3.0%. 4. In treatment, herb-medication is 86.1%, consultation is 7.9%, acupuncture is 17.8%, moxibution is 2.0%, venesection is 14.8%, aromatherapy is 4.9%, chimsband is 16.8%.

한방병원 산후조리센터 내 신생아에 대한 연구

강미선,장규태,김장현,Kang Mi-Sun,Chang Gyu-Tae,Kim Jang-Hyun 대한한방소아과학회 2001 대한한방소아과학회지 Vol.15 No.2

We studied 100 neonates to enter a Dongguk University Oriental Hospital Postpartum Care Center, during 9 months from February 10. 2001 to November 4. 2001. The conclusion is following. 1. Newborn sex ratio was 1.70. 2. Delivery method : Normal vaginal delivery was 66 and cesarean section was 34. 3. Gestation age : Premature infants less than 37 weeks were 2 term infants from 37 to 41 weeks were 98 and post-term infants 42 or more weeks were zero. 4. Period between birth and admission : First to fifth day was 66 sixth to tenth day was 32 and eleventh or more day was 2. 5. Period of admission : 1 to 7 days were 8. 8 to 14 days were 65. 15 to 21 days were 23. and 22 to 28 days were 4. 6. Weight : Birth weight less than 2500g was 3. 2500 to 3999g was 92. and 4000g or more was 5. 7. Height : Zero week after birth the average height was 48.8cm, one week after birth was 50.0cm, two weeks after birth was 51.8cm, three weeks after birth was 53.2cm, four weeks after birth was 54.5cm. 8. Head circumference : Zero week after birth the average head circumference was 34.6cm, one week after birth was 35.3cm, two weeks after birth was 35.7cm, three weeks after birth was 36.3cm, four weeks after birth was 36.8cm. 9. Chest circumference : Zero week after birth the average chest circumference was 33.2cm, one week after birth was 33.5cm, two weeks after birth was 34.4cm, three weeks after birth was 35.1cm, four weeks after birth was 36.6cm. 10. Feeding : There was not breast feeding, artificial feeding was 8, and mixing feeding was 92. 11. Jaundice : Physiologic jaundice was 10, pathologic jaundice was 1.

『문법에서 시작하는 일본어교육』의 문제점과 그 검증

강미선 ( Mi Sun Kang ) 한국일어일문학회 2014 日語日文學硏究 Vol.89 No.1

본 연구에서는 언어적 지식 전달에 치중하는 교육실천의 문제점을 지적하 고, 실제의 문법항목을 대상으로 한 공백타스크를 통해 그 문제점의 진위를 검증하였다. 커뮤니케이션을 위한 일본어교육이 단순히 일본어의 언어적 구조를 알기 위한 지식 전달교육에 치중할 경우, 학습자에게는 <지식으로서의 문법능력이 그대로 실제의 언어운용에 연결된다>고 하는 학습신념을 심어준다. 이러한 의 식의 진위를 검증하기 위하여 본론에서는 학습자의 기습문법항목인 「テク ル」를 사용하여 공백타스크를 행하였다. 한국인학습자 62명과 일본어모어화 자 62명을 대상으로 한 공백타스크의 조사결과를 정리하면 다음과 같다. (1) 한국인학습자의 경우「じゃ、60円の切手を5枚()」뒤에 이어지는 표현패턴으 로서, 1)「「買ってください」2)「お願いします」3)「買って+ほしい·もらえ る」4)「テクル」를 사용한 의뢰표현이 나타났다. 이에 반해 일본어모어화자 는 1)「お願いします」와 2)「テクル」를 사용한 의뢰표현만이 보였다. (2) 한국인학습자는「買う」라고 하는 동사를 사용하여 공백을 채울 경우 「買 う」뒤에 「テクル」를 붙이지 않고 그대로 의뢰표현을 쓰는 경향이 강하게 나타났다. 즉,「買ってください」「買ってほしい」「買ってもらえる」와 같 은 표현이 전체표현의 55%에 달했다. 이러한 표현패턴은 일본어모어화자에게 는 보이지 않았다. 이에 반해 일본인모어화자는「買う」라고 하는 동사를 사용 하여 공백을 채울 경우 100%의 조사대상자가「買う」뒤에 「テクル」를 접속 시켜 「買ってきてください」 와 같은 의뢰표현을 행하였다. (3) 한국인 학습자의 경우 「じゃ、60円の切手を5枚」뒤에 이어지는 표현으로 「テクル」를 사용한 학습자는 전체 조사협력자의 10%에 해당되며, 전원 중급 이상의 학습자들이다. (4) 이번 공백타스크 조사를 통해, 학습자가「テクル」는 한국어의 대응표현으로 「아/어오다」라고 하는 언어적 지식을 가지고 있어도, 인간관계나 표현주체의 표현의도 등이 관여하는 실제 장면에서는 「テクル」의 언어운용이 어렵다는 사실이 밝혀졌다. 이러한 조사 결과를 바탕으로 <언어적지식의 문법능력이 그 대로 실제의 언어운용에 연결된다>고 하는 학습자의 학습신념은 적절하지 않 다는 것이 입증되었다. 이러한 연구는, 언어적 지식 전달에 치중하는 교육실천의 문제점을 자각하 고, 앞으로 커뮤니케이션을 위한 초급일본어교육이 나아가야 할 방향을 생각하 는 토대적 연구를 지향한다. In this study, we pointed out the problems of an educational practice focusing on the linguistic knowledge delivery, and verified the authenticity of the problems. In case the Japanese education for communication focuses simply on the knowledge delivery to know the linguistic structure of Japanese language, it inspires a learner with the learning belief <the grammar ability as the knowledge is connected to the practical language management as it is.>. We performed the task to verify the authenticity of this awareness. (1) In case of Korean learners, as the expression patterns following「じゃ、60円 の切手を5枚, there appeared the expressions of the request using 1)「「買っ てください」2)「お願いします」3)「買って+ほしい·もらえる」4)「テ クル」. In contrast, Japanese native speakers, used only the request expressions using 1)「お願いします」and 2)「テクル」. (2) In case they fill the space by using a verb of 「買う」, Korean learners had a strong tendency not to put「テクル」after 「買う」、but to the request expressions as it is. That is, the expressions like「買ってください」「買って +ほしい·もらえる」accounted for 55% of the whole Theses expression patterns were not seen in Japanese native speakers. (3) In case of Korean learners, the learners using 「テクル」marks 10% of the whole survey respondents, and all of them are of higher level. (4) Through this survey, we verified the fact that 「テクル」has the knowledge of Korean「아/어오다, but the fact that it doesn``t guarantee the language management of a practical scene which the expression intention of the expression subject of human relation is engaged in. Through this study, we realized the problems of Japanese education focused on a linguistic knowledge, and consider the direction toward which the elementary Japanese education for communicationadvances in future.

웹툰에 나타난 신화적 상상력

강미선 ( Mi Sun Kang ) 가톨릭대학교 콘텐츠산업과 문화정책연구소 2011 디지털콘텐츠와 문화정책 Vol.5 No.-

아버지 양육참여도와 유아의 자아탄력성 간의 관계에서 유아 행복감의 매개효과

강미선 ( Kang Mi Sun ),김혜순 ( Kim Hye Soon ) 미래유아교육학회 2017 미래유아교육학회지 Vol.24 No.4

본 연구의 목적은 아버지의 양육참여도와 유아의 자아탄력성 간의 관계에서 유아 행복감의 매개효과가 나타나는지를 규명하는 것이었다. 서울시에 위치한 유아교육기관에 재원중인 만 3세~5세 유아와 아버지 191쌍을 연구대상으로 하였다. 설문지로 유아의 자아탄력성과 행복감 그리고 아버지의 양육참여도가 평가되었다. 수집된 자료는 SPSS/WIN 20.0과 AMOS 20.0 통계 프로그램을 활용하여 신뢰도분석과 빈도분석, 기술통계분석, 상관분석, 경로분석 및 매개효과 검증을 위한 Sobel test가 이루어졌다. 본 연구의 결과는 다음과 같다. 첫째, 아버지의 양육 참여도와 유아의 행복감, 유아의 자아탄력성 간의 상관관계는 각각 정적 상관성이 나타났다. 둘째, 아버지의 양육참여도와 유아의 자아탄력성 간의 관계에서 유아 행복감의 완전 매개효과가 나타났다. 이어서 매개변수로서 유아의 행복감이 자아탄력성에 미치는 영향에 대한 시사점이 논의되었다. The purpose of this study was to examine the mediation effects of young children’s happiness on the relationships between paternal involvement and their young children’s ego-resilience. The participants of this study were 191 pairs fathers and their young children who attended kindergartens and day-care centers in Seoul. The collected data were analyzed using SPSS/WIN 20.0 and AMOS 20.0. For the data analysis, reliability analysis, frequency analysis, descriptive statistic analysis, correlation analysis, path analysis were conducted. The results of the study were as follows: First, there were significant positive correlations among paternal involvement, their children’s ego resilience and happiness respectively. Second, there was a significant mediation effect of young children’s happiness on the relationships between paternal involvement and their young children’s ego resilience. Additionally, several implications of mediation effects of young children’s happiness on the relationships between paternal involvement and their young children's ego-resilience were concerned.

참가 초기의 인지능력이 무용성취와 무용참가의 지속성에 미치는 영향

강미선(Kang Mi Sun),이예순(Lee Yee Soon) 한국스포츠사회학회 1999 한국스포츠사회학회지 Vol.12 No.-

신문광고의 크기와 형태 변형이 광고효과에 미치는 영향

강미선(Kang, Mi-Sun) 한국광고홍보학회 2002 광고연구 Vol.0 No.57