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      • 特發性 總輸膽管擴張症 : Report of 3 Cases

        張泰守,金斗觀,尹健鎬,李東植 慶北大學校 醫科大學 1966 慶北醫大誌 Vol.7 No.2

        During recent 6 years (from April 1960 to March 1966) we have experienced three cases of the idiopathic dilatation of the common bile duct (choledochal cyst) which is one of the relatively rare congenital anomalies of the biliary system. The incidence of our cases was 3 out of 150,000. Two were women and another was man. According to the classification of Alonso-Lej etal. two were choledochal cysts and one was choledochocele. Pertain to the age of onset the former two were 26 (during 2nd trimester of pregnancy) and 42, and the latter was 30. The all three cases had upper gastro-intestinal tract symptoms such as indigestion, nausea, vomting and epigastric fullness which was thought to be due to compression of the gastro-intestinal tract by the cystic dilation of the common bile duct. The characteristic clinical triad; jaundice, RUQ abdominal pain and papable mass was present in the cases of choledochal cyst. Though there is no standard diagnostic criteria, increasing interest and awareness of surgeons, clinical triads and symptoms, various roentgenologic studies including upper GI series, oral cholecystogram, Ⅳ cholangiography, are helpful for the diagnosis of this disease preoperatively. Operative cholangiography must be done as a routine, if possible. It is the most valuable diagnostic clue when surgeon encountered this condition unexpectedly during operation. The only definitive treatment of this disease is operative. Various operative procedures which designed to establish a bypass of the bile flow into the gastrointestinal canal has been carried out. Different types of the operative procedures were applied on each of our three cases; choledochocystoduodenostomy with transient external drainage for one choledocal cyst, side to side choledochocystojejunostomy with Braun's anastomosis for the other one and side to end choledochojejunostomy (Roux-en Y) for the choledochocele, for whom side to side duodenojejunostomy was added for the prevention of passage disturbance of the duodenum. Of all three cases the postoperative course was uneventul except the pregnant woman delivered a premature baby on the third postoperative day. Short term follow up was very satisfactory. A biopsy taken from one choledochal cyst showed the extensive thickening, fibrosis of the common bile duct and lack of epithelium. There were islands of epithelium scattered in the fibrotic tissue. The infiltration of polymorphonuclear leukocytes, mononuclear leukocytes and macrophages proved acute and chronic inflammation.

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