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      • SCOPUSKCI등재

        식도정맥류 출혈의 내시경적 결찰요법의 임상적고찰

        정경태,박병수,최호순,고정희,박강서,조병석,이현상,최덕례 대한소화기내시경학회 1994 Clinical Endoscopy Vol.14 No.3

        Endoscopic infection sclerotherapy(EIS) has been shown to be the most effective simple method for control of bleeding and eradication of varices. This method has been accepted widely as a standard treatment of bleeding esophageal varices. However, EIS may be associated with undesirable local and systemic complications. Endoscopic variceal ligation(EVL) was first described in 1986 by Stiegmann et al, which consists of mechanical ligation and thrombosis of varices using elastic $quot;0$quot;-ring. EVL has been shown to control active bleeding and to eradicate varices when sessions are repeated. The purpose of this study was to compare with change of esophageal variceal form, with respect to safety, efficacy and complications of EVL in the each sessions. We performed EVL in 43 patients who had recently bled from esophageal varices. Total 679 variceal ligations were performed during 174 separyte EVL sessians. Eighteen(94.7%) of those actively bleeding(19 patients) at initial treatment had bleeding controlled at initial session. During the study period two patients died after 1st and 3rd session, one who died from aggravation of concomitant hepatoma with rebleeding, the other died from early massive rebleeding after 3rd session. Rebleeding, before eradicates varices, occured in 7 patients(16.3%) two patients had bled from varices with aggravation of concomitant hepatoma, other 2 patients had bled from early varices ligation, other 3 patients had bled from re-varices formation in fundus of the stomach. Varices were eradicated or reduced to F₁ in 36 patients(87.8%) of the 41 follow up patients. Each patient received mean 15.8 ligations and 4.1 sessions during the 1st to 6th sessions. Eradication rate of varices(F_0) has increased from the 3rd to the 4th session periods. Improvement rate of varices(F₁) has increased from the 1st to the 3rd session periods. During the 5th or the 6h EVL sessions, eradication and improvement rate of esaphageal varices has been shown to decreased. During or after EVL, there were no major complications, except mild chest discomfort in 6 patients, early bleeding in 2 gatients, mild dysphagia in one patient of 43 patients. According to this study, EVL appears to control active variceal bleeding and eradicate varices with repeat treatments. It is a safe and effective treatment for esophageal varices bleeding. We recommended EVL as an alternative to EIS over the 5th sessions.

      • KCI등재

        Salmonella typhimurium lipid A를 처리한 식세포 존재 조건에서 mitogen에 유도되는 이자 세포의 증식억제

        정경태,강경숙 한국생명과학회 2007 생명과학회지 Vol.17 No.2

        사람의 장티푸스 연구는 생쥐에 감염되는 Salmonella typhimurium를 모델로 연구되고 있으며, 생쥐에 있어서 S. typhimurium의 감염은 이자세포의 증식반응을 감소시키는 것으로 알려져 있다. S. typhimurium lipid A의 처리가 T 세포 mitogen에 의한 이자 세포의 증식에 어떤 영향을 주는 가를 in vitro와 ex vivo 조건에서 알아 보았다. Lipid A 단독 처리는 이자 세포의 증식을 보였으나, lipid A 처리 후 T 세포 mitogen인 concanavalin A (Con A)와 phytohemagglutinin (PHA)에 의한 in vitro와 ex vivo 조건에서의 이차 처리는 오히려 세포증식이 억제되었다. Lipid A를 주사한 생쥐로부터 분리한 이자 세포에서 대식세포를 제거하였을 조건에서는 T 세포 mitogen에 의한 증식 효과가 유지되었으나 대식세포를 제거하지 않았을 경우에는 T 세포 mitogen에 의한 증식 효과가 억제되었다. Lipid A를 주사한 생쥐에서 얻은 대식세포를 포함한 이자세포의 숫자를 증가하면서 Lipid A를 주사하지 않은 생쥐에서 얻은 이자세포와 혼합 배양하였을 때 Lipid A를 주사한 생쥐에서 얻은 대식세포를 포함한 이자세포의 숫자가 높을수록 Con A와 PHA에 의한 증식억제가 높게 측정되었다. 이러한 결과는 Con A와 PHA의 이자세포 증식 기능이 lipid A의 전처리에 의해 활성화된 대식세포의 직접적인 접촉 작용으로 억제된 것으로 생각된다. 본 연구의 결과를 바탕으로 억제에 관여하는 대식세포 표면분자를 밝히는 것이 사람의 장티푸스 연구에 도움이 되리라 생각된다. Infection with virulent or attenuated Salmonella typhimuriumhas known to induce reduction in proliferative responses of spleen cells. We investigated a role of lipid A from S. typhimurium, a B cell mitogen, on proliferation of spleen cells by T cell mitogens such as concanavaline A and phytohemagglutinin under in vitro and ex vivo conditions. Lipid A alone induced proliferation of spleen cells in vitroin a dose-dependent manner. However, subsequent treatment of concanavaline A or phytohemagglutin in after lipid A treatment induced proliferation suppression of murine spleen cells in vitro and ex vivo. Removal of macrophages from spleen cells, which were obtained from a lipid A-injected mouse, restored proliferation by concanavaline A and phytohemagglutinin, indicating that macrophages appeared to play a role in lipid A-induced suppression. Secreted molecules from macrophages did not accounted for the suppression because suppressive effect was not achieved when the supernatant from macrophage-containing spleen cell culture was conditioned to macrophage-depleted spleen cell culture. Co-culture of spleen cells from lipid A-treated and –untreated mice showed proliferation suppression as increasing cell numbers of lipid A-treated mouse. These data suggested that the cell-to-cell contact of macrophage with splenic lymphocyte cells is responsible for immune responses against lipid A, which is applicable to the case of human S. typhi infection.

      • KCI등재

        건축디자인에서의 크리스털(Crystal) 원리 적용에 관한 연구

        정경태 대한건축학회지회연합회 2019 대한건축학회연합논문집 Vol.21 No.1

        Nowadays, architects have sought variety of approaches to discovering a geometrical algorithm in nature and speculating new architectural forms. This study aims to establish the direction of the actual architectural design process based on the theoretical research of architectural design process using the properties of crystal. It is meaningful that the research may lead to in-depth and diverse form finding speculation in the morphological aspect. Furthermore, it is crucial to create unexpected architectural forms. In this study, the geometrical feature and material properties of crystal focusing Pyrite were analysed and applied from the initial stage of design to the final architectural implementation stage. The specific process to develop this is divided into four stages: investigation and analysis of crystal, prototype form, single crystalline space and implementation of crystal architecture. The new form finding is not an architect's creation, but an architectural form that is discovered within the algorithm, the design language inventory, and the materiality reflecting direct and indirect investigation and analysis of the crystal. It is anticipated that this study will prove invaluable reference, help architects and design professionals speculate unpredictable form finding, which is followed by the continued crystal analysis and application to architecture design. 오늘날 건축가들은 자연에서 기하학적 원리를 발견하여 새로운 건축적 형태를 찾아내기 위해 다양한 접근 방법을 모색해 왔다. 본 연구에서는 크리스털의 특성과 이를 적용한 건축디자인 사례들의 이론적 고찰을 바탕으로 실제 건축디자인 프로세스의 방향성을 정립하고자하였다. 이 연구를 통해 심도 있는 다양한 형태적 연구가 이뤄질 수 있고, 더 나아가 결과물로서 예상치 못한 흥미로운 건축적 형태를 창출해 낼 수 있다는데 그 의의가 있다. 이에 본 연구에서는 황철석(Pyrite)을 중심으로 크리스털의 기하학적 특징과 재료적 물성을 분석한 후, 디자인 초기 단계부터 최종 건축적 실현 단계까지 적용하였다. 이를 발전시켜 나가는 구체적인 프로세스를 크리스털에 대한 조사 분석, 프로토타입(prototype) 구축 , 크리스털라인 단일 공간, 크리스털 건축의 실현의 네 단계로 구분하여 제시하였다. 본 연구에서의 새로운 형태는 건축가가 창조해내는 것이 아닌 크리스털에 대한 직간접적인 조사 분석을 통해 구축된 알고리즘과 설정된 디자인 언어, 그리고 물성이 그대로 반영되어 그 건축적 형태가 발견되어지는 것이다. 건축가들, 그리고 디자인 관련 전문가들에게 예측 불가능한 새로운 형태를 찾기 위한 참고자료가 될 것이며, 향후 지속적인 크리스털에 대한 분석과 설계에의 적용에 관한 연구가 이뤄지기를 기대한다.

      • 도공지 품질과 Coater에서의 주행성 개선을 위한 코팅용 전분의 최적화

        정경태 강원대학교 부설 창강제지 기술연구소 1998 제지기술 Vol.- No.11

        전분 화학 연구를 통해 전분이 도공액 레올로지와 보수성 및 도공 구조에 미치는 영향이 드러났고 이러한 기초적 지식을 바탕으로 도공의 각기 다른 영역에서 발생되는 문제를 해결하기 위한 실험을 해하였다. 보다 많은 연구가 필요하겠지만 본 연구에서 경제적이면서 도공용 전분으로 완벽한 전분의 개발 시술을 얻었다.

      • 土壤栽培에 있어서 질소 및 칼리의 施肥水準이 오이의 生育, 收量 및 無機成分吸收에 미치는 影響

        具禹書,權成煥,鄭淳宰,鄭景泰 東亞大學校 大學院 1993 大學院論文集 Vol.18 No.-

        Cucumbers were grown at 5 levels of Potassium and Nitrogen to stuudy the effect of N,k concentration on growth, yield and content of mineral elements. 1. Growth and yields were increased in N treatment with 16g per plant, and wrer increase in K treatment with 16me per liter. 2. The content of mineral elements of in leaves were higher N teatment than K treatment in content of T-N and Mg, and content of P was high in K treatment. 3. The content of mineral of petiole, fruit and Xyleme sap. were detected. The content in Xyleme sap, was most in N treatment all content expect of NO₃-N. NO₃-N and K were contented a lot in petiole Ca was contented a little in fruit. In K treatment, No-N and K were contented a lot in petiole, and the others were contented in Xyleme sap. Ca was contented a little in fruit. 4. The content of mineral in soil was detected in N and K treatment content of mineral was a little after than before treatment P while in case of P content was higher before treatment 5. absorption of water in cucumber plants was increased in N treatment with 8g per plants, while decreased in the K treatment 8 me per plant. The contents of chlorophyll was increased as the levels of Nitrogen was increased in N treatment, however, decreased on young leave as the level of Poassium was incresed in K treatment.

      • KCI등재후보

        An Analytical Model with Three Sub-Regions for M2 Tide in the Yellow Sea and the East China Sea

        정경태,Chang Wook Park,Im Sang Oh,Jae Kwi So 한국해양과학기술원 2005 Ocean science journal Vol.40 No.4

        In this study an analytical tide model of uniform width with three sub-regions is presented. The three-subregions model takes into account step-like variations in depths in the direction of the channel as a way to examine the M2 tide of the East China Sea (ECS) as well as the Yellow Sea (YS). A modified Proudman radiation condition has been applied at the northern open head, while the sea surface elevation is specified at the southern open boundary. It is seen that, due to the presence of an abrupt change in depth, co-amplitude lines of the M2 tide are splitted to the east and west near the end of the ECS shelf region. Variations in depths, bottom friction and the open head boundary conditions all contribute to the determination of formation of amphidromes as well as overall patterns of M2 tidal distribution. It is seen that increasing water depth and bottom friction in the ECS shelf results in the westward shift of the southern amphidrome. There is however no hint at all of the well-known degenerated tidal pattern being formed. It is inferred that a lateral variation of water depth has to be somehow incorporated to represent the tidal patterns in ECS in a realistic manner. Regarding the radiation factor introduced by Fang et al. (1991), use of a value larger than one, possibly with a phase shift, appears to be a proper way of incorporating the reflected waves from the northern Yellow Sea (NYS).

      • On the algebra and Einstein's connection in 2-dimensional *g-UFT

        정경태,김성극 연세대학교 대학원 1980 延世論叢 Vol.16 No.2

        Many types of solutions of Einstein's equation hove been obtained so far. They are, however, too complicated for the first class, probably due to the complexity of the 4-dimensional generalized Riemann space X4. The main purpose of the present paper is to study the algebraic and differential geometric peoperties of 2-dimensional *gλν-unified field theory in X2, reducing the dimension to 2. In particular, the solution of Einstein's equation will be obtained in a simple tensorial form using a particular recurrence relation.

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